CHRNB1 and COPS6

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		CHRNB1	COPS6
Gene Name		cholinergic receptor, nicotinic, beta 1 (muscle)	COP9 signalosome subunit 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Acetylcholine-gated Channel Complex Cell Junction Synapse Postsynaptic Membrane	Nucleoplasm Cytoplasm COP9 Signalosome Extracellular Vesicular Exosome
	Molecular Function	Acetylcholine-activated Cation-selective Channel Activity Channel Activity Ligand-gated Ion Channel Activity Acetylcholine Receptor Activity Acetylcholine Binding	Protein Binding
	Biological Process	Postsynaptic Membrane Organization Skeletal Muscle Contraction Cation Transport Muscle Contraction Signal Transduction Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Ion Transmembrane Transport Behavioral Response To Nicotine Regulation Of Membrane Potential Muscle Fiber Development Neurological System Process Transmembrane Transport Cation Transmembrane Transport	Cullin Deneddylation Viral Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: COPS6 RAPSN	84 interactors: ANXA1 ANXA7 BTBD2 C1orf174 C4orf17 CASP3 CASP6 CASP7 CASP8 CCDC106 CDH10 CDKN1A CDKN2C CHRNB1 COPS2 COPS3 COPS4 COPS5 COPS8 COX17 COX5A CRELD1 CUL1 CUL5 DIS3L2 DLEU1 EDN1 EIF3E EMD EP300 ERH FAU GPS1 HMOX2 JUN LAMA4 LPL MAP7D1 MAPK6 MAPKAPK3 MIF MNAT1 MYCBP NEDD8 NR3C1 ORAI2 PAEP PAFAH1B3 PBX2 PDZK1IP1 PFKL PHYHIP PMF1 PRKRA PSAP PSMD11 PTEN QTRT1 RAB27A RBX1 RFC5 ROGDI RPA2 RPL15 S100A10 SAT1 SERPINA5 SERPINB9 SLC2A1 SMN1 SNRPG STK40 STX5 SULT1E1 TDGF1 TK1 TP53 TP63 TRDMT1 TRIB3 VIM WIPI2 ZEB2 ZNF24
Entrez ID		1140	10980
HPRD ID		01156	16735
Ensembl ID		ENSG00000170175	ENSG00000168090
Uniprot IDs		B7Z5H1 P11230 Q8IZ46	Q7L5N1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neuromuscular Synaptic Transmission Regulation Of Postsynaptic Membrane Organization Cullin Deneddylation Skeletal Muscle Acetylcholine-gated Channel Clustering Protein Deneddylation Synaptic Transmission, Cholinergic Postsynaptic Membrane Organization Receptor Clustering Neuromuscular Junction Development Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Neuron Death Positive Regulation Of Synaptic Transmission Protein Modification By Small Protein Removal	Cullin Deneddylation Protein Deneddylation Developmental Process Intrinsic Apoptotic Signaling Pathway Cellular Metabolic Process Anatomical Structure Development Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process Apoptotic Process Regulation Of Catalytic Activity Tissue Development Mitotic Cell Cycle Programmed Cell Death Apoptotic Signaling Pathway Response To Stress Cell Death Catabolic Process Death Regulation Of Cell Proliferation Mitotic Cell Cycle Process Cellular Response To Stress Response To Abiotic Stimulus G1/S Transition Of Mitotic Cell Cycle Regulation Of Apoptotic Process Regulation Of Phosphorylation Response To Organic Cyclic Compound Cell Cycle Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Metabolic Process Cell Cycle Phase Transition Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Cycle Organ Development Multicellular Organismal Development Epithelium Development Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cell Death Response To Stimulus Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Programmed Cell Death System Development Negative Regulation Of Cell Death Cellular Macromolecule Catabolic Process Response To Organic Substance Regulation Of Protein Kinase Activity Positive Regulation Of Cell Death
Tagcloud ?		anchor anchorage artificial assign bac backcross bacs bands bovine bta19 centromere chromosomes colour construct cryb1 fish gh1 hybrid interspecies library linkage locations loci map meiotic nf1 p4hb tp53 unresolved	aiming aip alignment boar brms1 chordc1 clues csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Difference) ?		anchor anchorage artificial assign bac backcross bacs bands bovine bta19 centromere chromosomes colour construct cryb1 fish gh1 hybrid interspecies library linkage locations loci map meiotic nf1 p4hb tp53 unresolved	aiming aip alignment boar brms1 chordc1 clues csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Intersection) ?