RASSF1 and CNKSR1

Number of citations of the paper that reports this interaction (PMID 15075335)
23

Data Source:
BioGRID (affinity chromatography technology, imaging technique)
HPRD (two hybrid, in vivo)

		RASSF1	CNKSR1
Gene Name		Ras association (RalGDS/AF-6) domain family member 1	connector enhancer of kinase suppressor of Ras 1
Image
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Microtubule Plasma Membrane Microtubule Cytoskeleton	Plasma Membrane Cell-cell Junction Cell Cortex
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Protein N-terminus Binding	Protein Binding, Bridging
	Biological Process	Cellular Response To DNA Damage Stimulus Cell Cycle Arrest Ras Protein Signal Transduction Positive Regulation Of Protein Ubiquitination Protein Stabilization Negative Regulation Of Cell Cycle Arrest	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ras Protein Signal Transduction Rho Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		33 interactors: ATP2B4 AURKA AURKB C7orf25 C8orf33 CDC20 CNKSR1 DAXX DDB1 E4F1 EXOSC8 HRAS IGFBP5 KCNE3 KDM1A MAP1B MAP1S MAPK8 MDM2 MOAP1 MST1 NUDT10 RASSF5 SAV1 STK3 STK4 SUV39H1 SUV39H2 TNFRSF10A TNFRSF1A TUBB TUBG1 XPA	18 interactors: ARHGEF1 BRAP CADM4 CYTH3 CYTH4 MAP2K2 MAP2K7 MAP3K10 PIN1 RAF1 RALGDS RASSF1 RHOA RHPN1 SMAD4 STK3 STK4 ZDHHC17
Entrez ID		11186	10256
HPRD ID		05470	11937
Ensembl ID		ENSG00000068028	ENSG00000142675
Uniprot IDs		Q9NS23	Q53GM7 Q969H4
PDB IDs		2KZU	1WWV
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Regulation Of Cell Death Cell Death Death Regulation Of Protein Binding Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Apoptotic Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Death Hippo Signaling Response To Abiotic Stimulus Mitotic Cell Cycle Process Positive Regulation Of Protein Modification Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Organ Growth Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Primitive Hemopoiesis Mitotic Cell Cycle Peptidyl-serine Phosphorylation Positive Regulation Of Transferase Activity Cell Cycle Response To UV Negative Regulation Of Protein Binding Signal Transduction By Phosphorylation Cellular Response To Stress Regulation Of Signaling Positive Regulation Of Protein Kinase Activity Organelle Organization Endocardium Development Positive Regulation Of Kinase Activity Positive Regulation Of Signal Transduction Hepatocyte Apoptotic Process Positive Regulation Of Protein Phosphorylation Regulation Of Signal Transduction Negative Regulation Of Gene Expression Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Cell Cycle Process Response To Light Stimulus Negative Regulation Of Developmental Growth Positive Regulation Of Cellular Metabolic Process	Regulation Of Signal Transduction Regulation Of Signaling Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Signal Transduction By Phosphorylation Positive Regulation Of Catalytic Activity Positive Regulation Of Protein Modification Process Regulation Of Catalytic Activity Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Transferase Activity Positive Regulation Of Signal Transduction Signaling Endocardium Development Small GTPase Mediated Signal Transduction Cell Communication Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Phosphorylation Neurotrophin Signaling Pathway MAPK Cascade Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Cellular Response To Stimulus Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Phosphorylation Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of MAPK Cascade Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Protein Metabolic Process Regulation Of Stress-activated MAPK Cascade Regulation Of Protein Kinase Activity Activation Of MAPKK Activity Positive Regulation Of MAPK Cascade Regulation Of Kinase Activity Protein Autophosphorylation Primitive Hemopoiesis Response To Stimulus Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cellular Metabolic Process
Tagcloud ?		bat braf cimp clinicopathological comparatively dapk develops discrete g15s gstp1 hierarchical hmlh1 inc india indian kras mint1 mint2 mint31 mononucleotide msi mss periodicals poorest rectal tp53 unfavorable v600e wiley
Tagcloud (Difference) ?		bat braf cimp clinicopathological comparatively dapk develops discrete g15s gstp1 hierarchical hmlh1 inc india indian kras mint1 mint2 mint31 mononucleotide msi mss periodicals poorest rectal tp53 unfavorable v600e wiley
Tagcloud (Intersection) ?