RASSF1 and MAP1B

Number of citations of the paper that reports this interaction (PMID 15205320)
30

Data Source:
HPRD (two hybrid, in vitro)

		RASSF1	MAP1B
Gene Name		Ras association (RalGDS/AF-6) domain family member 1	microtubule-associated protein 1B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Microtubule Plasma Membrane Microtubule Cytoskeleton	Cytoplasm Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Postsynaptic Density Cell Junction Dendritic Spine
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Protein N-terminus Binding	Structural Molecule Activity Protein Binding Microtubule Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Cell Cycle Arrest Ras Protein Signal Transduction Positive Regulation Of Protein Ubiquitination Protein Stabilization Negative Regulation Of Cell Cycle Arrest	Microtubule Bundle Formation Cellular Process Dendrite Development Negative Regulation Of Intracellular Transport Positive Regulation Of Axon Extension Mitochondrion Transport Along Microtubule Axon Extension Establishment Of Monopolar Cell Polarity
Pathways
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		33 interactors: ATP2B4 AURKA AURKB C7orf25 C8orf33 CDC20 CNKSR1 DAXX DDB1 E4F1 EXOSC8 HRAS IGFBP5 KCNE3 KDM1A MAP1B MAP1S MAPK8 MDM2 MOAP1 MST1 NUDT10 RASSF5 SAV1 STK3 STK4 SUV39H1 SUV39H2 TNFRSF10A TNFRSF1A TUBB TUBG1 XPA	27 interactors: ACTB ANP32A ARHGEF11 DYNLL1 EEF1D FOS GABRR1 GABRR2 GAN GSK3B LRRK2 MAG MAGOH MAP1A MAPK8 MARCH5 MINK1 NXF1 NXF2 PAFAH1B1 RASSF1 SNCA SPP1 STAU1 STRAP U2AF1 U2AF2
Entrez ID		11186	4131
HPRD ID		05470	01139
Ensembl ID		ENSG00000068028	ENSG00000131711
Uniprot IDs		Q9NS23	P46821 Q6PJD3 Q86X89
PDB IDs		2KZU
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Regulation Of Cell Death Cell Death Death Regulation Of Protein Binding Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Apoptotic Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Death Hippo Signaling Response To Abiotic Stimulus Mitotic Cell Cycle Process Positive Regulation Of Protein Modification Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Organ Growth Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Primitive Hemopoiesis Mitotic Cell Cycle Peptidyl-serine Phosphorylation Positive Regulation Of Transferase Activity Cell Cycle Response To UV Negative Regulation Of Protein Binding Signal Transduction By Phosphorylation Cellular Response To Stress Regulation Of Signaling Positive Regulation Of Protein Kinase Activity Organelle Organization Endocardium Development Positive Regulation Of Kinase Activity Positive Regulation Of Signal Transduction Hepatocyte Apoptotic Process Positive Regulation Of Protein Phosphorylation Regulation Of Signal Transduction Negative Regulation Of Gene Expression Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Cell Cycle Process Response To Light Stimulus Negative Regulation Of Developmental Growth Positive Regulation Of Cellular Metabolic Process	Nuclear Export MRNA Export From Nucleus RNA Localization Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus Regulation Of Mitochondrion Organization MRNA Transport RNA Transport Positive Regulation Of Mitochondrion Organization Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Cellular Component Organization Cellular Localization Negative Regulation Of Phosphorylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cytoplasmic Transport Negative Regulation Of Neuron Projection Development Substantia Nigra Development Regulation Of Cell Morphogenesis Termination Of RNA Polymerase II Transcription Signaling Cell Communication Cellular Response To Inorganic Substance Negative Regulation Of Cell Projection Organization Regulation Of Neuron Maturation Response To Metal Ion Regulation Of Axonogenesis Negative Regulation Of Cell Development Neural Nucleus Development Negative Regulation Of Protein Binding Synaptic Transmission Positive Regulation Of Programmed Cell Death Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cell Death Regulation Of Neuron Projection Development Negative Regulation Of Neuron Differentiation Neuron Projection Morphogenesis Immune System Process Cellular Response To Oxidative Stress DNA-templated Transcription, Termination Neurotrophin TRK Receptor Signaling Pathway Regulation Of Mitochondrial Fission MRNA 3'-end Processing Nervous System Development Neurotrophin Signaling Pathway Regulation Of Intracellular Transport MAPK Cascade
Tagcloud ?		bat braf cimp clinicopathological comparatively dapk develops discrete g15s gstp1 hierarchical hmlh1 inc india indian kras mint1 mint2 mint31 mononucleotide msi mss periodicals poorest rectal tp53 unfavorable v600e wiley	accelerated actin assembly barbed bundles cerevisiae coil coiled coisolated coronin coronins crn1delta crn1p cytoskeleton cytoskeletons dimerization filament filaments homologue linking links microtubule microtubules networks nucleation polymerization requirement saccharomyces stabilize
Tagcloud (Difference) ?		bat braf cimp clinicopathological comparatively dapk develops discrete g15s gstp1 hierarchical hmlh1 inc india indian kras mint1 mint2 mint31 mononucleotide msi mss periodicals poorest rectal tp53 unfavorable v600e wiley	accelerated actin assembly barbed bundles cerevisiae coil coiled coisolated coronin coronins crn1delta crn1p cytoskeleton cytoskeletons dimerization filament filaments homologue linking links microtubule microtubules networks nucleation polymerization requirement saccharomyces stabilize
Tagcloud (Intersection) ?