RASSF1 and MOAP1

Number of citations of the paper that reports this interaction (PMID 15949439)
34

Data Source:
HPRD (in vivo)

		RASSF1	MOAP1
Gene Name		Ras association (RalGDS/AF-6) domain family member 1	modulator of apoptosis 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Microtubule Plasma Membrane Microtubule Cytoskeleton	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Protein N-terminus Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Cell Cycle Arrest Ras Protein Signal Transduction Positive Regulation Of Protein Ubiquitination Protein Stabilization Negative Regulation Of Cell Cycle Arrest	Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Drugs
Diseases
GWAS			Endometriosis ( 23472165)
Protein-Protein Interactions		33 interactors: ATP2B4 AURKA AURKB C7orf25 C8orf33 CDC20 CNKSR1 DAXX DDB1 E4F1 EXOSC8 HRAS IGFBP5 KCNE3 KDM1A MAP1B MAP1S MAPK8 MDM2 MOAP1 MST1 NUDT10 RASSF5 SAV1 STK3 STK4 SUV39H1 SUV39H2 TNFRSF10A TNFRSF1A TUBB TUBG1 XPA	18 interactors: BAX BCL2 BCL2L1 CACNA1A CAMK2D CCDC85B DPPA2 FZR1 LATS1 MAGEH1 MBIP PNMA5 RASSF1 THOC1 TNFRSF10A TNFRSF1A UBC UBQLN4
Entrez ID		11186	64112
HPRD ID		05470	17580
Ensembl ID		ENSG00000068028	ENSG00000165943
Uniprot IDs		Q9NS23	Q96BY2
PDB IDs		2KZU
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Regulation Of Cell Death Cell Death Death Regulation Of Protein Binding Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Apoptotic Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Death Hippo Signaling Response To Abiotic Stimulus Mitotic Cell Cycle Process Positive Regulation Of Protein Modification Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Organ Growth Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Primitive Hemopoiesis Mitotic Cell Cycle Peptidyl-serine Phosphorylation Positive Regulation Of Transferase Activity Cell Cycle Response To UV Negative Regulation Of Protein Binding Signal Transduction By Phosphorylation Cellular Response To Stress Regulation Of Signaling Positive Regulation Of Protein Kinase Activity Organelle Organization Endocardium Development Positive Regulation Of Kinase Activity Positive Regulation Of Signal Transduction Hepatocyte Apoptotic Process Positive Regulation Of Protein Phosphorylation Regulation Of Signal Transduction Negative Regulation Of Gene Expression Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Cell Cycle Process Response To Light Stimulus Negative Regulation Of Developmental Growth Positive Regulation Of Cellular Metabolic Process See more	Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Extrinsic Apoptotic Signaling Pathway Cell Death Death Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Cellular Response To DNA Damage Stimulus Positive Regulation Of Apoptotic Process Apoptotic Signaling Pathway Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Apoptotic Process Programmed Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Neuron Apoptotic Process Regulation Of Metabolic Process Regulation Of Cell Cycle Process Release Of Cytochrome C From Mitochondria Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Regulation Of Nitrogen Utilization Regulation Of Neuron Death Regulation Of Mitochondrial Membrane Potential Regulation Of Phosphorylation Regulation Of Mitochondrial Membrane Permeability Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Regulation Of Membrane Permeability Intracellular Signal Transduction Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Cellular Metabolic Process Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Gamma Radiation Regulation Of Protein Phosphorylation Regulation Of Cell Death Negative Regulation Of Neuron Apoptotic Process Response To Abiotic Stimulus Neuron Apoptotic Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway See more
Tagcloud ?		bat braf cimp clinicopathological comparatively dapk develops discrete g15s gstp1 hierarchical hmlh1 inc india indian kras mint1 mint2 mint31 mononucleotide msi mss periodicals poorest rectal tp53 unfavorable v600e wiley	adopted alignment atp6 classical cndp2 constructed csde1 csfv dnaja1 dnaja4 fancl fever gaining gopc hemorrhage hnrnph1 indications interactive library ncbi ns2 pnma1 regarded suvec swine switching tmed4 umbilical y2h
Tagcloud (Difference) ?		bat braf cimp clinicopathological comparatively dapk develops discrete g15s gstp1 hierarchical hmlh1 inc india indian kras mint1 mint2 mint31 mononucleotide msi mss periodicals poorest rectal tp53 unfavorable v600e wiley	adopted alignment atp6 classical cndp2 constructed csde1 csfv dnaja1 dnaja4 fancl fever gaining gopc hemorrhage hnrnph1 indications interactive library ncbi ns2 pnma1 regarded suvec swine switching tmed4 umbilical y2h
Tagcloud (Intersection) ?