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CIT and GRIN1
Number of citations of the paper that reports this interaction (PMID
10862698
)
203
Data Source:
HPRD
(in vivo)
CIT
GRIN1
Gene Name
citron rho-interacting serine/threonine kinase
glutamate receptor, ionotropic, N-methyl D-aspartate 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ruffle
Vacuole
Plasma Membrane
Actin Cytoskeleton
Membrane
Golgi Cisterna
Neuronal Cell Body
Endoplasmic Reticulum
Plasma Membrane
Integral Component Of Plasma Membrane
Synaptic Vesicle
Cell Surface
Postsynaptic Density
N-methyl-D-aspartate Selective Glutamate Receptor Complex
Cell Junction
Dendrite
Dendrite Membrane
Neuron Projection
Synaptic Cleft
Terminal Bouton
Dendritic Spine
Synapse
Postsynaptic Membrane
Excitatory Synapse
Neuronal Postsynaptic Density
Molecular Function
Protein Serine/threonine Kinase Activity
Small GTPase Regulator Activity
Protein Binding
ATP Binding
Rho GTPase Binding
SH3 Domain Binding
PDZ Domain Binding
Metal Ion Binding
N-methyl-D-aspartate Selective Glutamate Receptor Activity
Extracellular-glutamate-gated Ion Channel Activity
Calcium Channel Activity
Calcium Ion Binding
Protein Binding
Calmodulin Binding
Glycine Binding
Glutamate Binding
Enzyme Binding
Voltage-gated Cation Channel Activity
Glutamate Receptor Binding
Neurotransmitter Binding
Protein Heterodimerization Activity
Biological Process
Mitotic Sister Chromatid Segregation
G2/M Transition Of Mitotic Cell Cycle
Cytokinesis
Protein Phosphorylation
Golgi Organization
Mitotic Nuclear Division
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Spermatogenesis
Regulation Of Actin Polymerization Or Depolymerization
Dendrite Development
Positive Regulation Of Cytokinesis
Intracellular Signal Transduction
Generation Of Neurons
Negative Regulation Of Dendrite Morphogenesis
Regulation Of Catalytic Activity
Conditioned Taste Aversion
Suckling Behavior
Response To Amphetamine
Cation Transport
Cellular Calcium Ion Homeostasis
Synaptic Transmission
Axon Guidance
Respiratory Gaseous Exchange
Long-term Memory
Adult Locomotory Behavior
Olfactory Learning
Visual Learning
Propylene Metabolic Process
Sensory Perception Of Pain
Pons Maturation
Cerebral Cortex Development
Ion Transmembrane Transport
Regulation Of Ion Transmembrane Transport
Social Behavior
Ionotropic Glutamate Receptor Signaling Pathway
Synaptic Transmission, Glutamatergic
Regulation Of Membrane Potential
Positive Regulation Of Apoptotic Process
Response To Morphine
Negative Regulation Of Neuron Apoptotic Process
Regulation Of Respiratory Gaseous Exchange
Response To Ethanol
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Ephrin Receptor Signaling Pathway
Regulation Of Long-term Neuronal Synaptic Plasticity
Rhythmic Process
Regulation Of Dendrite Morphogenesis
Regulation Of Axonogenesis
Protein Tetramerization
Response To Calcium Ion
Regulation Of Synapse Assembly
Calcium Ion Homeostasis
Regulation Of Excitatory Postsynaptic Membrane Potential
Prepulse Inhibition
Male Mating Behavior
Response To Fungicide
Calcium Ion Transmembrane Transport
Cellular Response To Manganese Ion
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways
EPHB-mediated forward signaling
Axon guidance
Activation of NMDA receptor upon glutamate binding and postsynaptic events
CREB phosphorylation through the activation of CaMKII
EPH-Ephrin signaling
CREB phosphorylation through the activation of Ras
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Unblocking of NMDA receptor, glutamate binding and activation
Ras activation uopn Ca2+ infux through NMDA receptor
Post NMDA receptor activation events
Transmission across Chemical Synapses
Drugs
L-Glutamic Acid
Meperidine
Orphenadrine
Dcka, 5,7-Dichlorokynurenic Acid
D-Serine
Cycloleucine
Milnacipran
Agmatine
Diseases
GWAS
Post-traumatic stress disorder (asjusted for relatedness) (
23726511
)
Protein-Protein Interactions
9 interactors:
DISC1
DLG4
GRIN1
GRIN2D
RAC1
RHOA
RHOB
RHOC
RND3
53 interactors:
ACTN2
AKAP9
CALM1
CAMK2A
CAMK2G
CANX
CDH2
CIT
CLTC
CTNNB1
DLG2
DLG3
DLG4
DLGAP4
DNM1
DRD1
DUSP4
EPHB2
EPHB4
FUS
FYN
GRIN2A
GRIN2B
GRIN2D
GRIN3A
HNRNPU
HRAS
HSPA1A
INA
LNX1
LRP8
MAP2
MAP2K2
MYH9
NANOS1
NEFL
NF1
PLAT
PLCG1
PPP2R1A
PPP2R2A
PRKCA
PRKCB
PRKCE
PRKCG
RAP2A
RPS6KA3
SP3
SPTAN1
SYNGAP1
TJP1
TRAF3
TUBA4B
Entrez ID
11113
2902
HPRD ID
09289
15926
Ensembl ID
ENSG00000122966
ENSG00000176884
Uniprot IDs
O14578
Q05586
Q59GW0
Q5VSF9
PDB IDs
2HQW
2NR1
3BYA
Enriched GO Terms of Interacting Partners
?
Axon Guidance
Axonogenesis
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Neuron Projection Morphogenesis
Locomotion
Cell Morphogenesis Involved In Differentiation
Skeletal Muscle Satellite Cell Migration
Neuron Projection Development
Movement Of Cell Or Subcellular Component
Cell Projection Morphogenesis
Generation Of Neurons
Cell Part Morphogenesis
Neurogenesis
Neuron Development
Response To External Stimulus
Cell Morphogenesis
Neuron Differentiation
Cell Projection Organization
Small GTPase Mediated Signal Transduction
Signal Transduction
Nervous System Development
Signaling
Cell Communication
Regulation Of Small GTPase Mediated Signal Transduction
Ephrin Receptor Signaling Pathway
Cytokinesis
Cellular Response To Stimulus
Neuromuscular Process
Cell Development
Intracellular Signal Transduction
Regulation Of Signaling
Regulation Of Cell Projection Organization
Negative Regulation Of Receptor-mediated Endocytosis
Cerebral Cortex Development
Cytoskeleton Organization
Cell Differentiation
Platelet Activation
Wound Healing
Startle Response
Actin Cytoskeleton Organization
Pallium Development
Cell-cell Junction Organization
Regulation Of Long-term Neuronal Synaptic Plasticity
Actin Filament-based Process
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Anatomical Structure Morphogenesis
Response To Stimulus
Locomotory Behavior
Synaptic Transmission
Cell-cell Signaling
Nervous System Development
Signaling
Locomotion
Cell Communication
Neurogenesis
Cell Differentiation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Response To Organic Substance
Generation Of Neurons
Neuron Projection Development
Neuron Development
Developmental Process
Cell Development
Neuron Differentiation
Response To External Stimulus
Signal Transduction
Cell Projection Organization
Movement Of Cell Or Subcellular Component
Enzyme Linked Receptor Protein Signaling Pathway
Multicellular Organismal Development
System Development
Cellular Response To Stimulus
Anatomical Structure Development
Axon Development
Axon Guidance
Regulation Of Synaptic Transmission
Regulation Of Synaptic Plasticity
Neuron Projection Morphogenesis
Cell Surface Receptor Signaling Pathway
Axonogenesis
Cellular Response To Organic Substance
Response To Wounding
Cell Morphogenesis Involved In Neuron Differentiation
Cell Morphogenesis Involved In Differentiation
Learning
Response To Stimulus
Regulation Of Signaling
Chemotaxis
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Response To Abiotic Stimulus
Fibroblast Growth Factor Receptor Signaling Pathway
Blood Coagulation
Hemostasis
Cell Projection Morphogenesis
Single-organism Behavior
Cellular Response To Growth Factor Stimulus
Learning Or Memory
Tagcloud
?
ag
allograft
atn
bdr
black
bloc
cadaver
cold
declining
drop
en
fatality
flush
hematocrit
immunosuppression
kidneys
lrd
match
mismatch
okt3
pra
predispose
preservation
procurement
prompted
recipient
rejection
uw
yr
Tagcloud (Difference)
?
ag
allograft
atn
bdr
black
bloc
cadaver
cold
declining
drop
en
fatality
flush
hematocrit
immunosuppression
kidneys
lrd
match
mismatch
okt3
pra
predispose
preservation
procurement
prompted
recipient
rejection
uw
yr
Tagcloud (Intersection)
?