CIT and RND3

Number of citations of the paper that reports this interaction (PMID 12773565)
72

Data Source:
BioGRID (two hybrid)

		CIT	RND3
Gene Name		citron rho-interacting serine/threonine kinase	Rho family GTPase 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Vacuole Plasma Membrane Actin Cytoskeleton Membrane Golgi Cisterna Neuronal Cell Body	Golgi Membrane Focal Adhesion Extracellular Vesicular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity Small GTPase Regulator Activity Protein Binding ATP Binding Rho GTPase Binding SH3 Domain Binding PDZ Domain Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Mitotic Sister Chromatid Segregation G2/M Transition Of Mitotic Cell Cycle Cytokinesis Protein Phosphorylation Golgi Organization Mitotic Nuclear Division Metaphase/anaphase Transition Of Mitotic Cell Cycle Spermatogenesis Regulation Of Actin Polymerization Or Depolymerization Dendrite Development Positive Regulation Of Cytokinesis Intracellular Signal Transduction Generation Of Neurons Negative Regulation Of Dendrite Morphogenesis Regulation Of Catalytic Activity	Cell Adhesion Small GTPase Mediated Signal Transduction Metabolic Process Actin Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS			Endometriosis ( 23472165) Type 2 diabetes ( 22238593)
Protein-Protein Interactions		9 interactors: DISC1 DLG4 GRIN1 GRIN2D RAC1 RHOA RHOB RHOC RND3	7 interactors: ARHGAP5 CIT PLXNB1 ROCK1 SKP2 UBC UBXN11
Entrez ID		11113	390
HPRD ID		09289	04233
Ensembl ID		ENSG00000122966	ENSG00000115963
Uniprot IDs		O14578	B2R838 P61587
PDB IDs			1M7B 2V55 4BG6
Enriched GO Terms of Interacting Partners?		Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Locomotion Cell Morphogenesis Involved In Differentiation Skeletal Muscle Satellite Cell Migration Neuron Projection Development Movement Of Cell Or Subcellular Component Cell Projection Morphogenesis Generation Of Neurons Cell Part Morphogenesis Neurogenesis Neuron Development Response To External Stimulus Cell Morphogenesis Neuron Differentiation Cell Projection Organization Small GTPase Mediated Signal Transduction Signal Transduction Nervous System Development Signaling Cell Communication Regulation Of Small GTPase Mediated Signal Transduction Ephrin Receptor Signaling Pathway Cytokinesis Cellular Response To Stimulus Neuromuscular Process Cell Development Intracellular Signal Transduction Regulation Of Signaling Regulation Of Cell Projection Organization Negative Regulation Of Receptor-mediated Endocytosis Cerebral Cortex Development Cytoskeleton Organization Cell Differentiation Platelet Activation Wound Healing Startle Response Actin Cytoskeleton Organization Pallium Development Cell-cell Junction Organization Regulation Of Long-term Neuronal Synaptic Plasticity Actin Filament-based Process Positive Regulation Of Excitatory Postsynaptic Membrane Potential Anatomical Structure Morphogenesis Response To Stimulus Locomotory Behavior	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process G2/M Transition Of Mitotic Cell Cycle Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Macromolecule Catabolic Process Intracellular Signal Transduction Rho Protein Signal Transduction Regulation Of Cytoskeleton Organization Proteolysis Cellular Response To Cell-matrix Adhesion Mitotic Cell Cycle Process G1/S Transition Of Mitotic Cell Cycle Catabolic Process Mitotic Cell Cycle Protein Polyubiquitination Cell Communication Neuron Projection Development Membrane To Membrane Docking Semaphorin-plexin Signaling Pathway Involved In Bone Trabecula Morphogenesis Apical Constriction Ras Protein Signal Transduction Regulation Of Organelle Organization Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Neuron Development Positive Regulation Of Rho GTPase Activity Metaphase/anaphase Transition Of Mitotic Cell Cycle Negative Regulation Of Dendrite Morphogenesis Cellular Response To Stimulus Cell Cycle Process Regulation Of Rho GTPase Activity Regulation Of Catalytic Activity Positive Regulation Of Cell Cycle Bleb Assembly Cellular Protein Metabolic Process Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Viral Protein Processing Neuron Differentiation Cell Projection Organization Negative Regulation Of Osteoblast Proliferation Myoblast Migration Regulation Of Cellular Component Size
Tagcloud ?		ag allograft atn bdr black bloc cadaver cold declining drop en fatality flush hematocrit immunosuppression kidneys lrd match mismatch okt3 pra predispose preservation procurement prompted recipient rejection uw yr	128a adjacent b1 bioinformatics blotting cdk4 dual expressions fresh hcc hepatocellular luciferase microrna mimics mir mtt nineteen pairs promoted promotes qrt reporter software targeting tissues transfected transfection utr viability
Tagcloud (Difference) ?		ag allograft atn bdr black bloc cadaver cold declining drop en fatality flush hematocrit immunosuppression kidneys lrd match mismatch okt3 pra predispose preservation procurement prompted recipient rejection uw yr	128a adjacent b1 bioinformatics blotting cdk4 dual expressions fresh hcc hepatocellular luciferase microrna mimics mir mtt nineteen pairs promoted promotes qrt reporter software targeting tissues transfected transfection utr viability
Tagcloud (Intersection) ?