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ZFP36
Gene Name
ZFP36 ring finger protein
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Molecular Function
DNA Binding
Single-stranded RNA Binding
MRNA Binding
Protein Binding
AU-rich Element Binding
Enzyme Binding
Protein Kinase Binding
C-C Chemokine Binding
MRNA 3'-UTR AU-rich Region Binding
Poly(A) RNA Binding
Metal Ion Binding
14-3-3 Protein Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Nuclear-transcribed MRNA Poly(A) Tail Shortening
MRNA Catabolic Process
Gene Expression
Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Translation Involved In Gene Silencing By MiRNA
Intracellular Signal Transduction
Response To Starvation
Negative Regulation Of Myeloid Cell Differentiation
Negative Regulation Of Inflammatory Response
RNA Destabilization
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
3'-UTR-mediated MRNA Stabilization
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Pathways
Regulation of mRNA stability by proteins that bind AU-rich elements
Tristetraprolin (TTP) destabilizes mRNA
Drugs
Diseases
GWAS
Protein-protein Interactions
22 interactors:
APP
CCDC85B
CDK6
DCP1B
DHX36
DNAJB1
EDC3
EXOSC6
EXOSC8
HMGB1
HOXC9
MAPK1
MAPKAPK2
NCL
NUP214
SFN
UPF2
XRN1
YWHAB
YWHAG
YWHAH
ZDHHC17
Entrez ID
7538
HPRD ID
01835
Ensembl ID
ENSG00000128016
Uniprot IDs
M0QY76
P26651
PDB IDs
4J8S
Enriched GO Terms of Interacting Partners
?
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
MRNA Catabolic Process
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
RNA Catabolic Process
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Aromatic Compound Catabolic Process
Gene Expression
Positive Regulation Of Mitochondrion Organization
MRNA Metabolic Process
RNA Metabolic Process
Regulation Of Mitochondrion Organization
Regulation Of Cellular Response To Heat
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Catabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
System Development
Apoptotic Process
Cellular Nitrogen Compound Metabolic Process
Programmed Cell Death
Intrinsic Apoptotic Signaling Pathway
Regulation Of Cellular Component Organization
Positive Regulation Of Organelle Organization
Cell Death
Death
Cellular Metabolic Process
Cellular Response To Heat
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Intracellular Transport
Regulation Of Protein Kinase Activity
Developmental Process
Nitrogen Compound Metabolic Process
Multicellular Organismal Development
Regulation Of Kinase Activity
Positive Regulation Of Intracellular Transport
Innate Immune Response
Anatomical Structure Development
Positive Regulation Of Signal Transduction
Immune Response
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Catabolic Process
Regulation Of Organelle Organization
Regulation Of Catalytic Activity
Response To Heat
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
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