TP53 and UBE2I

Number of citations of the paper that reports this interaction (PubMedID 8921390)
0

Data Source:
HPRD (in vitro)

		TP53	UBE2I
Description		tumor protein p53	ubiquitin conjugating enzyme E2 I
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Replication Fork Transcription Regulator Complex Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Endoplasmic Reticulum Centrosome Cytosol Cytoskeleton Nuclear Matrix Nuclear Body PML Body Transcription Repressor Complex Protein-containing Complex Site Of Double-strand Break Germ Cell Nucleus	Synaptonemal Complex Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Body PML Body Perinuclear Region Of Cytoplasm Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Presynaptic Cytosol Postsynaptic Cytosol SUMO Ligase Complex Transferase Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding Core Promoter Sequence-specific DNA Binding TFIID-class Transcription Factor Complex Binding Transcription Coactivator Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protease Binding P53 Binding DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity MRNA 3'-UTR Binding Copper Ion Binding Protein Binding Zinc Ion Binding Enzyme Binding Receptor Tyrosine Kinase Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Regulator Activity ATP-dependent DNA/DNA Annealing Activity Identical Protein Binding Histone Deacetylase Binding Metal Ion Binding Protein Heterodimerization Activity Protein-folding Chaperone Binding Protein Phosphatase 2A Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding 14-3-3 Protein Binding MDM2/MDM4 Family Protein Binding Disordered Domain Specific Binding General Transcription Initiation Factor Binding Molecular Function Activator Activity Molecular Condensate Scaffold Activity Promoter-specific Chromatin Binding	Nucleotide Binding Transcription Coregulator Binding RNA Binding Protein Binding ATP Binding Transcription Factor Binding Transferase Activity SUMO Transferase Activity Enzyme Binding HLH Domain Binding Small Protein Activating Enzyme Binding SUMO Conjugating Enzyme Activity RING-like Zinc Finger Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Mitophagy In Utero Embryonic Development Somitogenesis Release Of Cytochrome C From Mitochondria Hematopoietic Progenitor Cell Differentiation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment T Cell Lineage Commitment Response To Ischemia Nucleotide-excision Repair Double-strand Break Repair Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Protein Import Into Nucleus Autophagy Apoptotic Process DNA Damage Response Response To Oxidative Stress ER Overload Response Transforming Growth Factor Beta Receptor Signaling Pathway Ras Protein Signal Transduction Regulation Of Mitotic Cell Cycle Gastrulation Neuroblast Proliferation Negative Regulation Of Neuroblast Proliferation Central Nervous System Development Heart Development Circadian Rhythm Intracellular Protein Localization Negative Regulation Of DNA Replication Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Determination Of Adult Lifespan MRNA Transcription RRNA Transcription Response To Xenobiotic Stimulus Response To UV Response To Salt Stress Embryo Development Ending In Birth Or Egg Hatching Response To X-ray Response To Ionizing Radiation Response To Gamma Radiation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Programmed Cell Death Glial Cell Proliferation Viral Process Glucose Catabolic Process To Lactate Via Pyruvate Cerebellum Development Negative Regulation Of Cell Growth DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mitotic G1 DNA Damage Checkpoint Signaling Negative Regulation Of Telomere Maintenance Via Telomerase T Cell Differentiation In Thymus Tumor Necrosis Factor-mediated Signaling Pathway Cellular Response To Stress Regulation Of Tissue Remodeling Cellular Response To UV Multicellular Organism Growth Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Cell Population Proliferation Cellular Response To Glucose Starvation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Entrainment Of Circadian Clock By Photoperiod Mitochondrial DNA Repair Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Neuron Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Transcription Initiation-coupled Chromatin Remodeling Negative Regulation Of Proteolysis Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Antibiotic Fibroblast Proliferation Negative Regulation Of Fibroblast Proliferation Rhythmic Process Circadian Behavior Bone Marrow Development Embryonic Organ Development Protein Stabilization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Helicase Activity Protein Tetramerization Chromosome Organization Neuron Apoptotic Process Regulation Of Cell Cycle Hematopoietic Stem Cell Differentiation Negative Regulation Of Glial Cell Proliferation Type II Interferon-mediated Signaling Pathway Cardiac Septum Morphogenesis Positive Regulation Of Programmed Necrotic Cell Death Protein-containing Complex Assembly Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Thymocyte Apoptotic Process Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Thymocyte Apoptotic Process Necroptotic Process Cellular Response To Hypoxia Cellular Response To Xenobiotic Stimulus Cellular Response To Ionizing Radiation Cellular Response To Gamma Radiation Cellular Response To UV-C Stem Cell Proliferation Signal Transduction By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Reactive Oxygen Species Metabolic Process Cellular Response To Actinomycin D Positive Regulation Of Release Of Cytochrome C From Mitochondria Cellular Senescence Replicative Senescence Oxidative Stress-induced Premature Senescence Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Oligodendrocyte Apoptotic Process Positive Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Mitophagy Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of MiRNA Transcription Negative Regulation Of G1 To G0 Transition Negative Regulation Of MiRNA Processing Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of Pentose-phosphate Shunt Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Regulation Of Fibroblast Apoptotic Process Negative Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Stem Cell Proliferation Regulation Of Cellular Senescence Positive Regulation Of Cellular Senescence Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Ubiquitin-dependent Protein Catabolic Process Chromosome Segregation Mitotic Nuclear Membrane Reassembly Protein Sumoylation Positive Regulation Of Cell Migration Protein Modification Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of DNA-templated Transcription Modulation Of Chemical Synaptic Transmission Nuclear Export Cell Division
Pathways		Activation of NOXA and translocation to mitochondria Activation of PUMA and translocation to mitochondria Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Oncogene Induced Senescence DNA Damage/Telomere Stress Induced Senescence SUMOylation of transcription factors Autodegradation of the E3 ubiquitin ligase COP1 Association of TriC/CCT with target proteins during biosynthesis Pyroptosis TP53 Regulates Metabolic Genes Ub-specific processing proteases Ovarian tumor domain proteases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Interleukin-4 and Interleukin-13 signaling TP53 Regulates Transcription of DNA Repair Genes TP53 Regulates Transcription of Genes Involved in Cytochrome C Release TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain TP53 Regulates Transcription of Caspase Activators and Caspases TP53 Regulates Transcription of Death Receptors and Ligands TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Regulation of TP53 Expression Regulation of TP53 Activity through Phosphorylation Regulation of TP53 Degradation Regulation of TP53 Activity through Acetylation Regulation of TP53 Activity through Association with Co-factors Regulation of TP53 Activity through Methylation PI5P Regulates TP53 Acetylation G2/M DNA damage checkpoint G2/M Checkpoints Stabilization of p53 Transcriptional activation of cell cycle inhibitor p21 The role of GTSE1 in G2/M progression after G2 checkpoint Transcriptional Regulation by VENTX RUNX3 regulates CDKN1A transcription Regulation of PTEN gene transcription Regulation of PTEN gene transcription Loss of function of TP53 in cancer due to loss of tetramerization ability Signaling by ALK fusions and activated point mutants Regulation of NF-kappa B signaling Zygotic genome activation (ZGA) Factors involved in megakaryocyte development and platelet production PKR-mediated signaling	Meiotic synapsis Vitamin D (calciferol) metabolism SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMOylation of DNA damage response and repair proteins SUMOylation of transcription factors SUMOylation of transcription factors SUMOylation of ubiquitinylation proteins SUMOylation of transcription cofactors SUMOylation of transcription cofactors SUMOylation of SUMOylation proteins SUMOylation of intracellular receptors SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins SUMOylation of DNA methylation proteins SUMOylation of DNA methylation proteins SUMOylation of immune response proteins Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Processing of DNA double-strand break ends Formation of Incision Complex in GG-NER Negative regulation of activity of TFAP2 (AP-2) family transcription factors Negative regulation of activity of TFAP2 (AP-2) family transcription factors Postmitotic nuclear pore complex (NPC) reformation Maturation of nucleoprotein Maturation of nucleoprotein SARS-CoV-1 targets host intracellular signalling and regulatory pathways SUMOylation of nuclear envelope proteins PKR-mediated signaling Regulation of endogenous retroelements by KRAB-ZFP proteins Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs		Acetylsalicylic acid Zinc Triethyl phosphate AZD 3355 1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases		Chronic myeloid leukemia (CML) Breast cancer Non-small cell lung cancer Gastric cancer Adult T-cell leukemia Choriocarcinoma Esophageal cancer Glioma Pancreatic cancer Vulvar cancer Multiple myeloma Choroid plexus papilloma Ovarian cancer Hepatocellular carcinoma Squamous cell carcinoma Endometrial Cancer Penile cancer Cancer of the anal canal Hairy-cell leukemia Oral cancer Adrenal carcinoma Malignant melanoma Burkitt lymphoma Thyroid cancer Basal cell carcinoma Small cell lung cancer Gallbladder cancer Bladder cancer Laryngeal cancer Kaposi's sarcoma Cholangiocarcinoma Chronic lymphocytic leukemia (CLL) Li-Fraumeni syndrome, including: Classic Li-Fraumeni syndrome (LFS); LFS-like syndrome (LFSL) Malignant pleural mesothelioma Osteosarcoma Colorectal cancer
GWAS		Appendicular lean mass ( 33097823) Basal cell carcinoma ( 24403052 25855136 21946351 27539887 31174203 33549134) Birth weight ( 31043758) Brain morphology (MOSTest) ( 32665545) Cancer ( 28346444) Cutaneous malignant melanoma ( 32341527) Diastolic blood pressure ( 28135244 27841878 30578418) Esophageal squamous cell carcinoma ( 25129146) Glioblastoma ( 28346443 29743610) Glioblastoma (age-stratified) ( 30152087) Glioma ( 28346443 29743610) Haemorrhoidal disease ( 33888516) Keratinocyte cancer (MTAG) ( 31174203) LDL cholesterol levels ( 32203549) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Nevus count or cutaneous melanoma ( 32341527) Non-glioblastoma glioma ( 29743610 28346443) Pulse pressure ( 28135244 30578418 27841878) Red blood cell count ( 32888494) Sex hormone levels ( 26014426) Sporadic neuroblastoma ( 28545128) Uterine fibroids ( 31649266 31249589 30194396)	Appendicular lean mass ( 33097823) Idiopathic dilated cardiomyopathy ( 29495422) Monocyte percentage of white cells ( 32888494) Pulse pressure ( 30224653 30578418) Refractive error ( 32231278) Systolic blood pressure ( 30578418) White blood cell count ( 32888494)
Interacting Genes		505 interacting genes: ABL1 ACKR3 ACTA1 AGT AKAP5 AKT1 ANK2 ANKRD2 ANTKMT ANXA3 APBB2 APEX1 APPL1 APTX ARAF ARID1A ARID3A ARIH2 ARL3 ARRB1 ATF3 ATM ATR ATXN3 AURKA BAG5 BAG6 BAIAP2L1 BAK1 BANP BARD1 BCAS3 BCL2 BCL2L1 BCL2L12 BCL2L2 BCL6 BCR BLM BMP1 BRCA1 BRCA2 BRF1 BTBD2 BTK C10orf90 CABLES1 CABLES2 CAPG CAPN1 CARM1 CBLC CBLL2 CCDC106 CCDC3 CCL18 CCNA2 CCNG1 CCNH CCT5 CD40LG CDC14A CDC14B CDC25C CDC42 CDK1 CDK2 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDKN2B CDKN2C CEBPA CEBPZ CENPX CETP CHD3 CHEK1 CHEK2 CHUK COP1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS8 COX17 CR2 CRBN CREBBP CREBZF CSNK1A1 CSNK1D CSNK2A1 CSNK2B CUL4A CUL7 CUL9 CXXC1 DAPK3 DAXX DAZAP2 DCAF1 DCST1 DDRGK1 DDX20 DDX5 DGKZ DHCR24 DHFR DLEU1 DMTF1 DNAJC7 DNMT3A DNMT3L DTL DVL2 E2F1 E4F1 EAF2 EEF2 EFEMP2 EGLN3 EGR1 EHMT1 EHMT2 EIF2AK2 EIF2S2 ELL ELL3 EP300 EPHA2 EPHA3 ERBB2 ERCC2 ERCC3 ERCC6 ERH ESR1 FBXO11 FCAMR FGFR4 FOS FOXO4 FXYD6 GADD45A GGA1 GGA2 GGA3 GNL3 GPS1 GPS2 GPX2 GRWD1 GSK3B GSTM4 GTF2H1 GTF2H4 GYS2 HABP4 HDAC1 HDAC2 HDAC3 HECTD3 HECW1 HEY1 HIF1A HINFP HIPK1 HIPK2 HMGA1 HMGA2 HMGB1 HMGB2 HNF4A HNRNPUL1 HSP90AA1 HSP90AB1 HSP90B1 HSPA1A HSPA9 HSPB1 HTT HUWE1 IFI16 IKBKB ING1 ING4 ING5 IRF7 ITPK1 JDP2 JUN KAT2A KAT2B KAT5 KAT7 KAT8 KDM1A KDM4C KDM4D KIAA0087 KLF4 KLF6 KMT5A KPNA2 KPNB1 LACTB LAMA4 LAMTOR5 LATS2 LDB3 MAD2L1BP MAGEA2 MAGEB18 MAML1 MAP2K3 MAP2K5 MAP3K1 MAPK1 MAPK10 MAPK14 MAPK3 MAPK8 MAPK9 MAPKAPK5 MDC1 MDH1 MDM2 MDM4 MED1 MED17 MED21 MEN1 MET MEX3A MIF MLF2 MNAT1 MNDA MPHOSPH6 MSL2 MSX1 MTA1 MTA2 MUC1 MUL1 MVP MYBBP1A MYC NABP1 NABP2 NAP1L1 NAT10 NCL NCOA1 NCOA2 NCOA3 NDN NEDD8 NEIL3 NF2 NFKBIA NFYA NFYB NGFR NMT1 NMT2 NOP53 NPM1 NQO1 NR0B2 NR3C1 NR4A1 NRON NSD2 NTHL1 OGT OTUB1 OTUD3 OTUD5 PADI1 PAFAH1B3 PARP1 PBK PCDHA4 PDGFRA PDLIM7 PELI1 PELI2 PELP1 PER2 PHB1 PIAS1 PIAS2 PIAS4 PIN1 PKM PLAGL1 PLCG2 PLK1 PLK3 PML PNP POLA1 PPA1 PPARGC1A PPIB PPM1D PPP1CA PPP1CC PPP1R13L PPP2CA PPP2R2B PPP4C PRIM1 PRKAB2 PRKCA PRKD1 PRKDC PRKN PRKRA PRMT1 PRPF8 PSMA3 PSMB3 PSMC5 PSMD11 PSMD4 PSME3 PTEN PTGS2 PTK2 PTTG1 RAB4A RAB7A RAD51 RAG1 RANBP9 RAP1B RBBP6 RBCK1 RBPJ RCHY1 RELA RING1 RNF125 RNF128 RNF138 RNF187 RNF38 RNF6 RPA1 RPA2 RPS6KA1 RPS6KA2 RPS6KA3 RRM2 RRM2B RSL1D1 RUNX3 S100A1 S100A2 S100A4 S100A6 S100A8 S100B SAT1 SCAMP1 SERPINB9 SETD7 SFN SHISA5 SIN3A SIN3B SIRT1 SIRT5 SLC9A9 SMAD2 SMAD3 SMARCA4 SMARCB1 SMARCD1 SMN1 SMYD2 SNRPN SOCS1 SP1 SP3 SRC SRSF1 SSBP1 SSTR3 STAMBP STARD10 STAT6 STK11 STK4 STUB1 STX5 SUB1 SULT1E1 SUMO1 SYVN1 TADA3 TAF1 TAF1A TAF1B TAF1C TAF9 TAF9B TBP TCF4 TEAD2 TEC TEP1 TFAP2A TFAP2C TFDP1 TFIP11 THAP12 THAP8 THRB TK1 TOP1 TOP1MT TOP2A TOP2B TOPORS TP53BP1 TP53BP2 TP53INP1 TP53RK TP63 TP73 TRIAP1 TRIM21 TRIM39 TRIM41 TRIM65 TRIM67 TSC22D1 TSG101 TTK TWIST1 TXN UBB UBE2A UBE2D2 UBE2I UBE2K UBE2L3 UBE2M UBE2N UBE2Q1 UBE2V2 UBE3A UBE4B UFD1 UFL1 UHRF1 UHRF2 UIMC1 USP19 USP21 USP24 USP28 USP3 USP42 USP49 USP7 UTP14A VRK1 WDR33 WDR5 WDR82 WRN WT1 WWOX WWP1 XAF1 XPO1 XRCC6 YBX1 YWHAG YWHAZ YY1 YY2 ZBTB49 ZBTB5 ZCCHC10 ZHX1 ZIC3 ZMIZ2 ZNF148 ZNF24 ZNF302 ZNF679 ZNF839 ZNHIT1	486 interacting genes: - ACTB ADAR ADARB1 ADD3 AGR2 AGTRAP AKAP17A ANAPC4 ANXA1 APEX1 APP AR ARHGDIA ARK2N ARL13B ARL6IP1 ARNT ARRB2 ATF2 ATF3 ATF7IP ATXN1 AURKA AURKB BANP BCAM BCL11A BCL2L1 BEND5 BHLHE40 BIRC3 BIRC7 BLM BLMH BMAL1 BMI1 BTBD3 CALU CAMK2D CAMK2G CAMSAP2 CARD9 CARM1 CASP2 CASP8AP2 CBLC CBS CBX4 CCDC6 CD2AP CDC37 CDCA8 CDH4 CDR2L CEBPA CEBPD CEBPE CENPX CFL2 CFTR CHD3 CHD4 CHFR CHMP1A CHMP4B CHUK CLDN2 CLK2 COG1 CORO2A CREB1 CREBBP CREBL2 CREM CSGALNACT2 CSK CSNK2B CTBP2 CTNNA1 CYP4F2 DACH1 DAXX DCTD DDX21 DDX24 DDX39A DDX39B DDX5 DES DHX9 DMC1 DNM1 DNMT3A DNMT3B DPPA2 DPYSL2 DRG1 DTX3L DZIP3 EDARADD EDF1 EGR2 EIF2AK2 EIF2B1 EIF5A ELK1 EP300 ERCC6 ESR1 ETS1 ETV1 ETV6 EXO1 EXOSC9 FADD FAF1 FAM118A FANCM FAS FATE1 FHIT FHL3 FLI1 FMR1 FOS FOXL2 FOXM1 GCM1 GIPC2 GLUL GMCL1 GMCL2 GMEB1 GMEB2 GOLGA1 GOLGA2 GOLGB1 GRIP1 GTF2I H4C16 HABP4 HDAC1 HDAC4 HDAC5 HDAC7 HGS HIC1 HIF1A HIPK1 HIPK2 HIPK3 HIRA HMBOX1 HMGB1 HMGN2 HMGXB4 HNF4A HNRNPC HNRNPCL1 HNRNPD HNRNPK HNRNPLL HNRNPM HNRNPU HSF1 HSF2 HSF2BP IKBKG IKZF1 IKZF3 IKZF5 IMPDH1 IPO13 IQGAP1 JUN JUNB KAT2A KAT6B KCNA5 KCNK1 KCTD1 KDM1A KHSRP KLF3 KLF5 KLHL12 KLHL2 KMT5A KRT19 KRTAP5-2 KRTAP5-4 KRTAP5-9 KTN1 LATS1 LCE1D LCE1F LCE2C LCE3B LCE5A LMNA LMNB1 LMO2 LNX2 LONRF1 LRSAM1 MALL MAP2K1 MAP3K1 MAP3K5 MAPK1IP1L MARCHF5 MAT2A MATR3 MBD4 MDM2 MECOM MED7 MEF2C MGRN1 MIPOL1 MITF MKRN3 MLX MORC3 MRTFA MTA1 MYB MYBBP1A MYH9 NACC1 NAF1 NAT10 NCOR2 NFE2 NFKBIA NHP2 NIN NMI NOL6 NONO NOP2 NOP56 NOP58 NOX5 NR1D2 NR1H2 NR1H3 NR1I2 NR3C1 NR3C2 NR5A1 NR5A2 NRIP1 NSD3 NUDCD3 NVL PAICS PARK7 PARP1 PAX5 PCNA PDLIM7 PDPK1 PDZK1 PELI1 PEX10 PHC1 PIAS1 PIAS2 PIAS3 PIAS4 PIM1 PLAAT4 PLAGL1 PLK1 PML POLR1H POU1F1 POU2F1 PPARA PPARG PPARGC1A PPCDC PPM1J PRKAA2 PRKDC PROP1 PRPF40A PRPF8 PRPSAP1 PSMC3 PSMC6 PSME3 PTEN PUF60 RABAC1 RAD18 RAD51 RAD52 RAD54B RAD54L2 RANBP2 RANGAP1 RB1 RBBP5 RBBP6 RBBP8 RBM14 RBM25 RC3H2 RCBTB2 RFPL3 RHOB RHOXF2 RIPK2 RNF10 RNF111 RNF115 RNF128 RNF133 RNF144B RNF151 RNF185 RNF4 RNF40 ROCK2 RORB RPL11 RPL7 RPL8 RPRD1B RPS3A RPS6KA6 RUSF1 RWDD3 RXRA SAE1 SALL1 SART1 SATB1 SCNN1A SEMA6A SEPTIN1 SETBP1 SETDB1 SETX SFPQ SH3KBP1 SIAH1 SIAH2 SIRT1 SKIL SLC2A1 SLC2A4 SLX4 SMAD4 SNAI2 SND1 SNIP1 SNRNP200 SOCS6 SOX10 SOX4 SOX5 SOX9 SP100 SP3 SPECC1L SPOP SREBF1 SREBF2 SRF SRSF4 SSRP1 STAT1 STIP1 STMN2 STX1A STX1B STX2 SUMO1 SUMO1P1 SUMO2 SUMO3 SUPT7L SUZ12 SYMPK TAB2 TAF1 TAF10 TAF12 TAF5 TBL1X TBL1XR1 TBP TCERG1 TCF3 TCF4 TDG TDP2 TERF2 TFAP2A TFAP2B TFAP2C TFCP2 TFG THAP1 THRA THRB TIGD3 TLK2 TNFRSF1A TOP1 TOP2A TOP2B TOPORS TP53 TP63 TP73 TRAF2 TRAF3 TRAF4 TRAF6 TRIM21 TRIM23 TRIM24 TRIM27 TRIM28 TRIM29 TRIM38 TRIM41 TRIM54 TRIM63 TRIM72 TRIP13 TRPS1 TSHZ2 TSN TSNAX TTN TXLNB UBA2 UBE2K UBQLN1 UBQLN2 UBXN1 UCHL1 UNC119 USP25 USP36 VENTX VEZF1 VHL WNK1 WT1 WWP2 XBP1 XIAP XRCC1 XRCC5 YY1 ZBED1 ZBTB1 ZBTB16 ZBTB2 ZBTB26 ZBTB7A ZBTB8A ZBTB9 ZC3H10 ZCCHC12 ZCCHC7 ZEB2 ZG16 ZIC1 ZMYM2 ZNF106 ZNF24 ZNF408 ZNF446 ZNF451 ZNF618 ZNF646 ZNF837 ZNRD2
Entrez ID		7157	7329
HPRD ID		01859	09045
Ensembl ID		ENSG00000141510	ENSG00000103275
Uniprot IDs		A0A087WT22 A0A087WXZ1 A0A087X1Q1 H2EHT1 K7PPA8 P04637 Q53GA5	A8K503 P63279 Q7KZS0
PDB IDs		1A1U 1AIE 1C26 1DT7 1GZH 1H26 1HS5 1JSP 1KZY 1MA3 1OLG 1OLH 1PES 1PET 1SAE 1SAF 1SAK 1SAL 1TSR 1TUP 1UOL 1XQH 1YC5 1YCQ 1YCR 1YCS 2AC0 2ADY 2AHI 2ATA 2B3G 2BIM 2BIN 2BIO 2BIP 2BIQ 2F1X 2FEJ 2FOJ 2FOO 2GS0 2H1L 2H2D 2H2F 2H4F 2H4H 2H4J 2H59 2J0Z 2J10 2J11 2J1W 2J1X 2J1Y 2J1Z 2J20 2J21 2K8F 2L14 2LY4 2MEJ 2MWO 2MWP 2MWY 2MZD 2OCJ 2PCX 2RUK 2VUK 2WGX 2X0U 2X0V 2X0W 2XWR 2YBG 2YDR 2Z5S 2Z5T 3D05 3D06 3D07 3D08 3D09 3D0A 3DAB 3DAC 3IGK 3IGL 3KMD 3KZ8 3LW1 3OQ5 3PDH 3Q01 3Q05 3Q06 3SAK 3TG5 3TS8 3ZME 4AGL 4AGM 4AGN 4AGO 4AGP 4AGQ 4BUZ 4BV2 4HFZ 4HJE 4IBQ 4IBS 4IBT 4IBU 4IBV 4IBW 4IBY 4IBZ 4IJT 4KVP 4LO9 4LOE 4LOF 4MZI 4MZR 4QO1 4RP6 4RP7 4X34 4XR8 4ZZJ 5A7B 5AB9 5ABA 5AOI 5AOJ 5AOK 5AOL 5AOM 5BUA 5ECG 5G4M 5G4N 5G4O 5HOU 5HP0 5HPD 5LAP 5LGY 5MCT 5MCU 5MCV 5MCW 5MF7 5MG7 5MHC 5MOC 5O1A 5O1B 5O1C 5O1D 5O1E 5O1F 5O1G 5O1H 5O1I 5OL0 5UN8 5XZC 6FF9 6FJ5 6GGA 6GGB 6GGC 6GGD 6GGE 6GGF 6LHD 6R5L 6RJZ 6RK8 6RKI 6RKK 6RKM 6RL3 6RL4 6RL6 6RM5 6RM7 6RWH 6RWI 6RWS 6RWU 6RX2 6RZ3 6S39 6S3C 6S40 6S9Q 6SHZ 6SI0 6SI1 6SI2 6SI3 6SI4 6SIN 6SIO 6SIP 6SIQ 6SL6 6SLV 6T58 6V4F 6V4H 6VQO 6VR1 6VR5 6VRM 6VRN 6W51 6XRE 6ZNC 7B46 7B47 7B48 7B49 7B4A 7B4B 7B4C 7B4D 7B4E 7B4F 7B4G 7B4H 7B4N 7BWN 7DHY 7DHZ 7DVD 7EAX 7EDS 7EEU 7EL4 7NMI 7RM4 7V97 7XZX 7XZZ 7YGI 8A31 8A32 8A92 8CG7 8DC4 8DC6 8DC7 8DC8 8E7A 8E7B 8GCR 8HLL 8HLM 8HLN 8J8N 8OXM 8OXO 8QWK 8QWL 8QWM 8QWN 8QWO 8QWP 8R1F 8R1G 8RBA 8RBB 8RBC 8RCI 8UQR 8WD2 8XP5 9BR4 9C5S 9CHT	1A3S 1KPS 1Z5S 2GRN 2GRO 2GRP 2GRQ 2GRR 2O25 2PE6 2PX9 2XWU 3A4S 3UIN 3UIO 3UIP 4W5V 4Y1L 5D2M 5F6D 5F6E 5F6U 5F6V 5F6W 5F6X 5F6Y 5FQ2 6SYF 8ODR 9B62
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Cellular Response To Stress Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Protein Modification Process Regulation Of RNA Biosynthetic Process Regulation Of DNA-templated Transcription DNA Damage Response Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Intracellular Signal Transduction DNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Protein Metabolic Process Protein Metabolic Process P53 Binding Negative Regulation Of Macromolecule Metabolic Process Regulation Of Programmed Cell Death Negative Regulation Of Metabolic Process Regulation Of Cellular Response To Stress Post-translational Protein Modification Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Chromatin Organization Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Chromatin Remodeling Negative Regulation Of RNA Biosynthetic Process DNA Repair Response To Stress Negative Regulation Of RNA Metabolic Process Transferase Activity Regulation Of Intracellular Signal Transduction Cytosol Regulation Of Signal Transduction By P53 Class Mediator	Nucleus Nucleoplasm Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Macromolecule Metabolic Process Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding PML Body RNA Polymerase II-specific DNA-binding Transcription Factor Binding Nucleic Acid Metabolic Process Sequence-specific DNA Binding DNA-binding Transcription Factor Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Cellular Response To Stress DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-templated Transcription Nucleobase-containing Compound Metabolic Process Protein Modification By Small Protein Conjugation Transcription Cis-regulatory Region Binding Zinc Ion Binding
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