GPS1 and SAP130

Number of citations of the paper that reports this interaction (PubMedID 18173839)
43

Data Source:
BioGRID (affinity chromatography technology, pull down)

		GPS1	SAP130
Description		G protein pathway suppressor 1	Sin3A associated protein 130
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol COP9 Signalosome	Nucleus Nuclear Speck Sin3-type Complex
	Molecular Function	GTPase Inhibitor Activity Protein Binding
	Biological Process	Protein Deneddylation JNK Cascade Protein Neddylation Regulation Of Protein Neddylation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation RHOBTB1 GTPase cycle	HATs acetylate histones NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS			Anti-saccade response ( 29064472) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		26 interacting genes: CNOT2 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS8 CUL1 CUL2 CUL3 CUL5 ELOB IP6K1 ITPK1 OGT RBX1 SAP130 SENP8 SKP1 SKP2 TBC1D17 TP53 TRIM55 TRIM63 VHL	7 interacting genes: ARID4B CCR9 CUL2 GPS1 MYC SMAD3 USP7
Entrez ID		2873	79595
HPRD ID		15991	18015
Ensembl ID		ENSG00000169727	ENSG00000136715
Uniprot IDs		A0A096LP07 A0A096LPJ3 A0A9L9PX62 A0A9L9PXT0 A8K070 C9JFE4 Q13098	A0A2R8YDB8 H7BXF5 Q96DP1 Q9H0E3
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N 8H38 8H3A 8H3F
Enriched GO Terms of Interacting Partners?		Protein Deneddylation Post-translational Protein Modification Protein Modification By Small Protein Conjugation Protein Neddylation Protein Modification Process Regulation Of Protein Neddylation Regulation Of Post-translational Protein Modification COP9 Signalosome Ubiquitin Ligase Complex Scaffold Activity Protein Modification By Small Protein Removal Cullin-RING Ubiquitin Ligase Complex Protein Metabolic Process Protein K48-linked Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process SCF Ubiquitin Ligase Complex Protein Ubiquitination Regulation Of Protein Modification Process Cytosol G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Macromolecule Metabolic Process Regulation Of Protein Metabolic Process Proteolysis DeNEDDylase Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Nucleoplasm Nucleus Modification-dependent Protein Catabolic Process Mitotic Cell Cycle Phase Transition Macromolecule Catabolic Process Catabolic Process Cell Cycle Phase Transition Protein Polyubiquitination Ubiquitin Protein Ligase Binding Proteasomal Protein Catabolic Process Regulation Of TORC1 Signaling Proteolysis Involved In Protein Catabolic Process Protein Monoubiquitination Cul5-RING Ubiquitin Ligase Complex Ubiquitin-protein Transferase Activity Protein Catabolic Process Cul2-RING Ubiquitin Ligase Complex Negative Regulation Of TORC1 Signaling Regulation Of TOR Signaling Positive Regulation Of Epithelial Cell Apoptotic Process Cytoplasm Intrinsic Apoptotic Signaling Pathway VCB Complex Negative Regulation Of TOR Signaling	Nucleoplasm Chromatin Remodeling Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Intracellular Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Chromatin Organization MAPK Cascade Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Acinar Cell Proliferation Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Positive Regulation Of MiRNA Transcription JNK Cascade Positive Regulation Of MiRNA Metabolic Process Regulation Of Intracellular Transport Epigenetic Regulation Of Gene Expression Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Ubiquitin Protein Ligase Binding Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of MiRNA Transcription T Cell Activation Regulation Of Stem Cell Population Maintenance Myc-Max Complex Regulation Of Acinar Cell Proliferation Regulation Of Cellular Response To Growth Factor Stimulus Sterol Response Element Binding Regulation Of MiRNA Metabolic Process Paraxial Mesoderm Morphogenesis Cis-regulatory Region Sequence-specific DNA Binding Apoptotic Signaling Pathway NK T Cell Proliferation Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Symbiont-mediated Disruption Of Host Cell PML Body CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?