GPS1 and IP6K1

Number of citations of the paper that reports this interaction (PMID 25349427)
0

Data Source:
BioGRID (pull down)

		GPS1	IP6K1
Gene Name		G protein pathway suppressor 1	inositol hexakisphosphate kinase 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm COP9 Signalosome	Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	GTPase Inhibitor Activity Protein Binding	Inositol Hexakisphosphate 5-kinase Activity ATP Binding Inositol-1,4,5-trisphosphate 3-kinase Activity Inositol Hexakisphosphate 1-kinase Activity Inositol Hexakisphosphate 3-kinase Activity
	Biological Process	Inactivation Of MAPK Activity Cell Cycle JNK Cascade Cullin Deneddylation	Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation
Pathways			Synthesis of IPs in the nucleus Synthesis of pyrophosphates in the cytosol Inositol phosphate metabolism
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		20 interactors: COPS2 COPS3 COPS5 COPS6 COPS7A COPS8 CUL1 CUL2 CUL3 CUL5 DDB1 IP6K1 ITPK1 JUN RBX1 SENP8 SKP1 SKP2 TBC1D17 TP53	6 interactors: CACNA1A COPS2 DDB1 EXOSC7 GPS1 RAB3IL1
Entrez ID		2873	9807
HPRD ID		15991	07379
Ensembl ID		ENSG00000169727	ENSG00000176095
Uniprot IDs		C9JFE4 Q13098	Q92551
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Deneddylation Cullin Deneddylation Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Protein Monoubiquitination Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Modification Process G1/S Transition Of Mitotic Cell Cycle Proteolysis Viral Process Cellular Macromolecule Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Cell Cycle Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Cellular Protein Metabolic Process Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Cycle Arrest Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Catabolic Process Mitotic Cell Cycle Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Metabolic Process Mitotic Cell Cycle Notch Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Circadian Rhythm Cell Cycle Process Negative Regulation Of Cell Proliferation Regulation Of Cell Proliferation Regulation Of DNA-templated Transcription In Response To Stress Response To Abiotic Stimulus Cell Communication Metabolic Process Negative Regulation Of Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Signal Transduction Histone H2A Monoubiquitination Cell Cycle Histone H2A Ubiquitination Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Signaling	Cullin Deneddylation Protein Deneddylation Cerebellar Molecular Layer Development Protein Modification By Small Protein Removal Vestibular Nucleus Development Positive Regulation By Virus Of Viral Protein Levels In Host Cell Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Gamma-aminobutyric Acid Secretion Regulation Of Acetylcholine Secretion, Neurotransmission Rhythmic Synaptic Transmission UV-damage Excision Repair Positive Regulation Of Viral Release From Host Cell Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Gamma-aminobutyric Acid Transport Chloride Ion Homeostasis Negative Regulation Of Hormone Biosynthetic Process Pons Development Histone H2A Monoubiquitination Cerebellar Purkinje Cell Differentiation Histone H2A Ubiquitination Cerebellar Purkinje Cell Layer Morphogenesis Nucleotide-excision Repair, DNA Damage Removal Aromatic Compound Catabolic Process Histone Monoubiquitination Reflex Positive Regulation Of Viral Genome Replication Regulation Of Viral Release From Host Cell Behavioral Response To Pain Neuromuscular Synaptic Transmission
Tagcloud ?		abnormal assigned calculated cop count css escc esophageal esophagectomy follows glasgow gps0 gps2 hypoalbuminemia indexes kaplan log lymphocyte meier neutrophil nlr nlr0 nlr1 nlr2 platelet predicts prognostic rank	2c acetyl adapt begun conversely cues demethylase depend dissociation epigenetic epigenetically fundamental h3k9 h3k9me3 hexakisphosphate influences inositol ip7 jmjd2c jumonji knockout lysine modifications pyrophosphate pyrophosphates repression rnai translates trimethyl
Tagcloud (Difference) ?		abnormal assigned calculated cop count css escc esophageal esophagectomy follows glasgow gps0 gps2 hypoalbuminemia indexes kaplan log lymphocyte meier neutrophil nlr nlr0 nlr1 nlr2 platelet predicts prognostic rank	2c acetyl adapt begun conversely cues demethylase depend dissociation epigenetic epigenetically fundamental h3k9 h3k9me3 hexakisphosphate influences inositol ip7 jmjd2c jumonji knockout lysine modifications pyrophosphate pyrophosphates repression rnai translates trimethyl
Tagcloud (Intersection) ?