TSPAN4 and PLSCR4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TSPAN4	PLSCR4
Description		tetraspanin 4	phospholipid scramblase 4
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Membrane Vesicle	Nucleus Plasma Membrane Membrane
	Molecular Function	Antigen Binding Integrin Binding Protein Binding	Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding CD4 Receptor Binding
	Biological Process	Protein-containing Complex Assembly	Plasma Membrane Phospholipid Scrambling Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Cellular Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS		Falling risk ( 32999390)	Femur bone mineral density x serum urate levels interaction ( 34046847) Lymphocyte count ( 32888494)
Interacting Genes		49 interacting genes: CATSPER1 CD46 CD81 CD9 CHRD CLDN11 CLEC2D CREB3 CREB5 CYSRT1 EVA1A FCHO1 FRS3 GNE GRN GUCD1 HOXA1 ITGA3 ITGA6 ITGB1 KRTAP10-1 KRTAP10-8 KRTAP4-11 KRTAP4-5 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE2B LCE2D LCE3A LCE3C LCE3D LCE4A LRRC25 LTB4R2 MDFI MGAT5B MKRN3 NBPF19 NOTCH2NLA NR4A3 OTX1 PHLDA1 PLSCR4 SGPL1 TEKT4 TMEM106A VGLL3	63 interacting genes: ABHD17A ADAMTSL4 APLN ATP23 CES1 CFAP68 CLPP CRCT1 DAZAP2 DDIT4L EFEMP2 FCHO1 GATA1 HDHD3 HOXA1 INTS11 ITGB4 KLHL38 KPRP KRT82 KRTAP1-5 KRTAP10-8 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP3-1 KRTAP3-3 KRTAP4-12 KRTAP4-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LCE1A LCE1C LCE2B LCE5A LPXN MTUS2 NID2 NOTCH2NLA OXER1 PCSK5 PLA2G10 PLSCR1 RAMAC RBP3 RBPMS RPS27A SLC15A2 SSC4D TEKT5 TENM4 TRIM42 TRIP13 TSPAN4 UBA52 UBB UBC YPEL3 ZNF34
Entrez ID		7106	57088
HPRD ID		04033	07401
Ensembl ID		ENSG00000214063	ENSG00000114698
Uniprot IDs		A8MVV6 O14817	E9PHR9 Q9NRQ2
PDB IDs			3Q5U
Enriched GO Terms of Interacting Partners?		Keratinization Epidermis Development Keratin Filament Intermediate Filament Integrin Alpha6-beta1 Complex Integrin Alpha3-beta1 Complex Myoblast Fusion Involved In Skeletal Muscle Regeneration Myoblast Fusion Integrin Complex Cellular Response To Low-density Lipoprotein Particle Stimulus Cellular Response To Lipoprotein Particle Stimulus Cell-cell Fusion Syncytium Formation Syncytium Formation By Plasma Membrane Fusion Cerebellar Climbing Fiber To Purkinje Cell Synapse Identical Protein Binding CAMP Response Element Binding Regulation Of Cell Motility Hair Cycle Regulation Of Locomotion Integrin Binding Mesodermal Cell Differentiation Tissue Development	Intermediate Filament Keratinization Keratin Filament Protein Tag Activity Endocytic Vesicle Membrane Epidermis Development Protein Binding Female Meiosis I
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