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TSPAN4 and ITGA3
Number of citations of the paper that reports this interaction (PMID
10734060
)
35
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology)
HPRD
(in vivo)
TSPAN4
ITGA3
Gene Name
tetraspanin 4
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Focal Adhesion
Integral Component Of Membrane
Vesicle
Plasma Membrane
Focal Adhesion
Integrin Complex
External Side Of Plasma Membrane
Cell Surface
Basolateral Plasma Membrane
Growth Cone
Filopodium Membrane
Integrin Alpha3-beta1 Complex
Receptor Complex
Perinuclear Region Of Cytoplasm
Excitatory Synapse
Extracellular Vesicular Exosome
Invadopodium Membrane
Cell Periphery
Synaptic Membrane
Molecular Function
Antigen Binding
Integrin Binding
Glycoprotein Binding
Fibronectin Binding
Protease Binding
Integrin Binding
Protein Binding
Collagen Binding
Protein Domain Specific Binding
Laminin Binding
Metal Ion Binding
Protein Heterodimerization Activity
Biological Process
Protein Complex Assembly
Neuron Migration
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Heart Development
Blood Coagulation
Memory
Positive Regulation Of Gene Expression
Positive Regulation Of Epithelial Cell Migration
Positive Regulation Of Cell-substrate Adhesion
Positive Regulation Of Neuron Projection Development
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Wnt Signaling Pathway
Extracellular Matrix Organization
Lung Development
Regulation Of BMP Signaling Pathway
Negative Regulation Of Cell Projection Organization
Response To Gonadotropin
Negative Regulation Of Rho Protein Signal Transduction
Exploration Behavior
Response To Drug
Skin Development
Mesodermal Cell Differentiation
Leukocyte Migration
Maternal Process Involved In Female Pregnancy
Nephron Development
Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane
Dendritic Spine Maintenance
Renal Filtration
Pathways
Laminin interactions
Integrin cell surface interactions
Basigin interactions
Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Protein-Protein Interactions
8 interactors:
CD46
CD81
CD9
CLDN11
ITGA3
ITGA6
ITGB1
NOTCH2NL
15 interactors:
ADAM9
BIN1
CALR
CD151
CD82
CD9
FHL2
FN1
HPS5
HSPD1
ITGB1
LGALS8
RABIF
TIMP2
TSPAN4
Entrez ID
7106
3675
HPRD ID
04033
05431
Ensembl ID
ENSG00000214063
ENSG00000005884
Uniprot IDs
A8MVV6
O14817
P26006
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Cell Adhesion
Positive Regulation Of Cell-substrate Adhesion
Integrin-mediated Signaling Pathway
Blood Coagulation
Hemostasis
Cell Adhesion Mediated By Integrin
Reproduction
Negative Regulation Of Rho Protein Signal Transduction
Cell Adhesion
Single Organism Reproductive Process
Cell-matrix Adhesion
Regulation Of Body Fluid Levels
Reproductive Process
Wound Healing
Regulation Of Cell-substrate Adhesion
Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane
Cell Junction Assembly
Regulation Of Cell Adhesion
Positive Regulation Of Protein Localization To Plasma Membrane
Cell-substrate Adhesion
Mesodermal Cell Differentiation
Leukocyte Migration
Response To Wounding
Response To Gonadotropin
Sexual Reproduction
Viral Entry Into Host Cell
Regulation Of Establishment Of Protein Localization To Plasma Membrane
Entry Into Host Cell
Multicellular Organism Reproduction
Regulation Of Protein Localization To Plasma Membrane
Negative Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Small GTPase Mediated Signal Transduction
Extracellular Matrix Organization
Extracellular Structure Organization
Negative Regulation Of Signal Transduction
Maternal Process Involved In Female Pregnancy
Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity
Negative Regulation Of Signaling
Mesoderm Formation
Mesoderm Morphogenesis
Locomotion
Interaction With Host
Cell-cell Junction Assembly
Viral Process
Positive Regulation Of Lymphocyte Proliferation
Positive Regulation Of Mononuclear Cell Proliferation
Single Fertilization
Formation Of Primary Germ Layer
Regulation Of Cell Proliferation
Movement Of Cell Or Subcellular Component
Cell Activation
Positive Regulation Of Cell Adhesion
Extracellular Matrix Organization
Extracellular Structure Organization
Calcium-independent Cell-matrix Adhesion
Cellular Component Assembly
Cell Junction Assembly
Leukocyte Activation
Positive Regulation Of Cell Development
Cell-cell Adhesion Mediated By Integrin
Regulation Of Neuron Differentiation
Positive Regulation Of Catalytic Activity
System Development
Regulation Of Cell Adhesion
Extracellular Matrix Disassembly
Cell Differentiation
Positive Regulation Of Endocytosis
Positive Regulation Of Metabolic Process
Cell Adhesion Mediated By Integrin
Muscle Cell Differentiation
Cardiac Muscle Cell Differentiation
Cell Adhesion
Regulation Of Neurogenesis
Multicellular Organismal Development
Cardiocyte Differentiation
Anatomical Structure Development
Lymphocyte Activation
Positive Regulation Of Neurogenesis
Blood Coagulation
Regulation Of Cell Development
Positive Regulation Of Cell Differentiation
Hemostasis
Immune System Process
B Cell Activation
Cell-matrix Adhesion
Response To Hormone
Regulation Of Endocytosis
Cardiac Muscle Tissue Development
Muscle Structure Development
Developmental Process
Regulation Of Catalytic Activity
Single Organismal Cell-cell Adhesion
Neurogenesis
Cell-substrate Adhesion
Positive Regulation Of Hydrolase Activity
Protein Maturation
Striated Muscle Cell Differentiation
Regulation Of Body Fluid Levels
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
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