OLFM4 and SYNE4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		OLFM4	SYNE4
Gene Name		olfactomedin 4	spectrin repeat containing, nuclear envelope family member 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Mitochondrion Plasma Membrane Secretory Granule Specific Granule Azurophil Granule Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Integral Component Of Nuclear Outer Membrane LINC Complex
	Molecular Function	Catalytic Activity Protein Homodimerization Activity Cadherin Binding
	Biological Process	Cell Adhesion Metabolic Process Regulation Of Necrotic Cell Death Regulation Of Apoptotic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Phagocytosis Negative Regulation Of Immune Response Protein Homooligomerization Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Neutrophil Extravasation	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways
Drugs
Diseases
GWAS		Immune response to anthrax vaccine ( 22658931) Obesity ( 23563607 22484627) Obesity-related traits ( 23251661)
Protein-Protein Interactions		5 interactors: APP C3 CCDC155 LDLRAD1 SYNE4	52 interactors: ABT1 ADIPOQ BRICD5 C10orf35 C3orf52 CD47 CEP19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FATE1 GADD45A GSK3B ITM2B KLC4 KLHL12 KLRG1 KTN1 MALL MARCH2 NAGK OCLN OLFM4 OSTCP1 PAQR5 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250
Entrez ID		10562	163183
HPRD ID		06580	08776
Ensembl ID		ENSG00000102837	ENSG00000181392
Uniprot IDs		Q6UX06	Q8N205
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromosome Localization To Nuclear Envelope Involved In Synapsis Synaptic Growth At Neuromuscular Junction Positive Regulation Of Type IIa Hypersensitivity Collateral Sprouting In Absence Of Injury Positive Regulation Of Activation Of Membrane Attack Complex Negative Regulation Of Endopeptidase Activity Collateral Sprouting Axon Midline Choice Point Recognition Establishment Of Epithelial Cell Apical/basal Polarity Negative Regulation Of Peptidase Activity Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Hypersensitivity Establishment Of Apical/basal Cell Polarity Positive Regulation Of Apoptotic Cell Clearance Polarized Epithelial Cell Differentiation Negative Regulation Of Proteolysis Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Negative Regulation Of Protein Processing Neuron Remodeling Regulation Of Endopeptidase Activity Establishment Of Monopolar Cell Polarity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Regulation Of Apoptotic Cell Clearance Complement Activation, Alternative Pathway Positive Regulation Of Inflammatory Response To Antigenic Stimulus Positive Regulation Of Humoral Immune Response Establishment Of Epithelial Cell Polarity Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Cellular Copper Ion Homeostasis Positive Regulation Of Protein Processing Regulation Of Triglyceride Biosynthetic Process Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Copper Ion Homeostasis Suckling Behavior Morphogenesis Of A Polarized Epithelium Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Acute Inflammatory Response Regulation Of Proteolysis Establishment Or Maintenance Of Apical/basal Cell Polarity Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Complement Activation Positive Regulation Vascular Endothelial Growth Factor Production Mating Behavior Positive Regulation Of Lipid Storage Regulation Of Triglyceride Metabolic Process	ER To Golgi Vesicle-mediated Transport Negative Regulation Of Binding Regulation Of Binding Golgi Vesicle Transport Adiponectin-activated Signaling Pathway Vesicle Fusion With Golgi Apparatus Negative Regulation Of Protein Binding Response To External Stimulus Regulation Of Glycogen (starch) Synthase Activity Cellular Response To Mechanical Stimulus Vesicle-mediated Transport Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Intracellular Signal Transduction
Tagcloud ?		abilities alleviate allografts alongside antibiotic antitumor bacteria bacteroides clostridium coccoides conferred cpt enterococcus herb intestinal intestine irinotecan kd018 lactobacillus leptum lgr5 mcp1 metabolize neomycin phy906 primers qpcr rectale streptomycin
Tagcloud (Difference) ?		abilities alleviate allografts alongside antibiotic antitumor bacteria bacteroides clostridium coccoides conferred cpt enterococcus herb intestinal intestine irinotecan kd018 lactobacillus leptum lgr5 mcp1 metabolize neomycin phy906 primers qpcr rectale streptomycin
Tagcloud (Intersection) ?