NEBL and GMCL1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NEBL	GMCL1
Gene Name		nebulette	germ cell-less, spermatogenesis associated 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Z Disc I Band Extracellular Vesicular Exosome	Nuclear Envelope Nuclear Matrix
	Molecular Function	Protein Binding Tropomyosin Binding Cytoskeletal Protein Binding Structural Constituent Of Muscle Filamin Binding Actin Filament Binding
	Biological Process	Cardiac Muscle Thin Filament Assembly	Regulation Of Transcription, DNA-templated Multicellular Organismal Development Spermatogenesis Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)
Protein-Protein Interactions		23 interactors: ACTB ACTN1 ACTN3 CCDC136 FAM9B GMCL1 GOLGA2 HOMER3 LZTS2 MAD1L1 MIPOL1 MYPN NUTM1 PRKAB2 TRAF1 TRAF2 TRIM27 TRIM55 TRIM63 XIRP1 XIRP2 ZDHHC17 ZYX	61 interactors: APLF APOL6 BYSL C21orf2 C5orf60 CCDC25 CHIC2 CIB3 CLK2 CUL3 EMD FAM167A FAM63A FKBP1B FOSL2 FOXR1 FRMD6 GAGE1 GAGE12B GAGE12I GAGE2E GAGE5 GLRX3 GMCL1P1 GRAMD1A HYKK IL17F KAT5 KIFC3 KPNA2 MID1 MID2 MORF4L1 MPPE1 MTRR NEBL NUMA1 PARD6B PARP16 PAX4 PBXIP1 PTPN7 QRICH1 RAD54B SHQ1 SLC15A3 SNX20 STK3 SUMO1 SUMO1P1 SYT17 TCEB3 TMPO TRIM13 TRIM38 TRIM54 TSG101 TSSC4 XAGE2 XAGE3 ZNF250
Entrez ID		10529	64395
HPRD ID		10403	13587
Ensembl ID		ENSG00000078114
Uniprot IDs		O76041 Q59FZ8	Q53SE7 Q96IK5
PDB IDs		4F14
Enriched GO Terms of Interacting Partners?		Actin Filament-based Process Cellular Component Assembly Actin Cytoskeleton Organization Cytoskeleton Organization Cell-cell Junction Organization Organelle Organization Adherens Junction Organization Actomyosin Structure Organization Focal Adhesion Assembly Cell-matrix Adhesion Protein K63-linked Ubiquitination Protein Trimerization Cell Junction Assembly Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell-substrate Adhesion Adherens Junction Assembly Signal Transduction Cell-substrate Junction Assembly Sarcomere Organization Regulation Of Metaphase Plate Congression Actin Filament Bundle Assembly Signaling Cell Communication Actin Filament Organization Negative Regulation Of Interleukin-2 Secretion Myofibril Assembly Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Protein Localization To Tight Junction Cellular Process Positive Regulation Of NF-kappaB Transcription Factor Activity	Protein Localization To Microtubule Double-strand Break Repair Regulation Of Viral Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Viral Transcription Negative Regulation Of Viral Release From Host Cell Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Axon Regeneration Regulation Of Viral Entry Into Host Cell Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Viral Transcription Protein Localization To Cytoskeleton Regulation Of Viral Release From Host Cell DNA Metabolic Process Cellular Protein Modification Process DNA Repair Trophectodermal Cell Differentiation Protein Modification By Small Protein Conjugation Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Proteasomal Protein Catabolic Process Nucleus Organization Regulation Of Gene Expression Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Cellular Localization Negative Regulation Of Microtubule Depolymerization Cardiac Muscle Thin Filament Assembly Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Ubiquitin-dependent Protein Catabolic Process Blastocyst Formation Response To Ionizing Radiation Modification-dependent Protein Catabolic Process Cellular Response To Interferon-gamma
Tagcloud ?		anatomical assumes bcc bccs binomial correction crnkl1 drivers exome genesis hot intermittent invex landscape lend melanomas mutational passengers patched permutation pick ptch1 sccs sequenced spots stat5b stringent uniform uniquely	asm atm bouquet compensate conjugating dmc1 doubling dsbs gadd45a haploid hop2 hr6b insignificant joining ku80 m1jcs mei1 meiosis mlh1 pairing preleptotene prophase segregates spermatocytes spermatogenesis spermiogenesis spo11 terf1 tnp1
Tagcloud (Difference) ?		anatomical assumes bcc bccs binomial correction crnkl1 drivers exome genesis hot intermittent invex landscape lend melanomas mutational passengers patched permutation pick ptch1 sccs sequenced spots stat5b stringent uniform uniquely	asm atm bouquet compensate conjugating dmc1 doubling dsbs gadd45a haploid hop2 hr6b insignificant joining ku80 m1jcs mei1 meiosis mlh1 pairing preleptotene prophase segregates spermatocytes spermatogenesis spermiogenesis spo11 terf1 tnp1
Tagcloud (Intersection) ?