NEBL and TRIM55

Number of citations of the paper that reports this interaction (PMID 18157088)
41

Data Source:
BioGRID (two hybrid)

		NEBL	TRIM55
Gene Name		nebulette	tripartite motif containing 55
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Z Disc I Band Extracellular Vesicular Exosome	Nucleus Cytoplasm Microtubule
	Molecular Function	Protein Binding Tropomyosin Binding Cytoskeletal Protein Binding Structural Constituent Of Muscle Filamin Binding Actin Filament Binding	Signal Transducer Activity Zinc Ion Binding Identical Protein Binding
	Biological Process	Cardiac Muscle Thin Filament Assembly	Signal Transduction
Pathways
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)	Response to statin therapy ( 22666496)
Protein-Protein Interactions		23 interactors: ACTB ACTN1 ACTN3 CCDC136 FAM9B GMCL1 GOLGA2 HOMER3 LZTS2 MAD1L1 MIPOL1 MYPN NUTM1 PRKAB2 TRAF1 TRAF2 TRIM27 TRIM55 TRIM63 XIRP1 XIRP2 ZDHHC17 ZYX	61 interactors: ACTA1 ANKRD1 ATP5B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1
Entrez ID		10529	84675
HPRD ID		10403	05927
Ensembl ID		ENSG00000078114	ENSG00000147573
Uniprot IDs		O76041 Q59FZ8	Q9BYV6
PDB IDs		4F14
Enriched GO Terms of Interacting Partners?		Actin Filament-based Process Cellular Component Assembly Actin Cytoskeleton Organization Cytoskeleton Organization Cell-cell Junction Organization Organelle Organization Adherens Junction Organization Actomyosin Structure Organization Focal Adhesion Assembly Cell-matrix Adhesion Protein K63-linked Ubiquitination Protein Trimerization Cell Junction Assembly Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell-substrate Adhesion Adherens Junction Assembly Signal Transduction Cell-substrate Junction Assembly Sarcomere Organization Regulation Of Metaphase Plate Congression Actin Filament Bundle Assembly Signaling Cell Communication Actin Filament Organization Negative Regulation Of Interleukin-2 Secretion Myofibril Assembly Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Protein Localization To Tight Junction Cellular Process Positive Regulation Of NF-kappaB Transcription Factor Activity	Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Protein Deubiquitination Protein Modification By Small Protein Removal Actin Filament-based Movement Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Muscle Contraction Actin Filament-based Process Cellular Protein Catabolic Process Protein Catabolic Process Muscle System Process Protein K48-linked Deubiquitination Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Striated Muscle Cell Development Cellular Protein Metabolic Process Muscle Structure Development Muscle Cell Development Protein K63-linked Deubiquitination Myofibril Assembly Proteolysis Cellular Protein Modification Process Striated Muscle Tissue Development Cardiac Muscle Tissue Morphogenesis Striated Muscle Cell Differentiation Muscle Tissue Development Muscle Tissue Morphogenesis Actomyosin Structure Organization Muscle Organ Morphogenesis Cardiac Muscle Tissue Development Protein Metabolic Process Muscle Organ Development Protein Modification By Small Protein Conjugation Muscle Cell Differentiation Myosin Filament Assembly Catabolic Process Actin Cytoskeleton Organization Skeletal Muscle Thin Filament Assembly Cytoskeleton Organization Skeletal Myofibril Assembly Response To Muscle Stretch Heart Morphogenesis Striated Muscle Contraction Cellular Process
Tagcloud ?		anatomical assumes bcc bccs binomial correction crnkl1 drivers exome genesis hot intermittent invex landscape lend melanomas mutational passengers patched permutation pick ptch1 sccs sequenced spots stat5b stringent uniform uniquely
Tagcloud (Difference) ?		anatomical assumes bcc bccs binomial correction crnkl1 drivers exome genesis hot intermittent invex landscape lend melanomas mutational passengers patched permutation pick ptch1 sccs sequenced spots stat5b stringent uniform uniquely
Tagcloud (Intersection) ?