NEBL and XIRP1

Number of citations of the paper that reports this interaction (PMID 23985323)
1

Data Source:
BioGRID (two hybrid, pull down, unspecified method, protein complementation assay)

		NEBL	XIRP1
Gene Name		nebulette	xin actin-binding repeat containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Z Disc I Band Extracellular Vesicular Exosome	Fascia Adherens
	Molecular Function	Protein Binding Tropomyosin Binding Cytoskeletal Protein Binding Structural Constituent Of Muscle Filamin Binding Actin Filament Binding	Actin Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Cardiac Muscle Thin Filament Assembly	Negative Regulation Of Cell Proliferation Regulation Of Membrane Potential Sarcomere Organization Cardiac Muscle Cell Development
Pathways
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)
Protein-Protein Interactions		23 interactors: ACTB ACTN1 ACTN3 CCDC136 FAM9B GMCL1 GOLGA2 HOMER3 LZTS2 MAD1L1 MIPOL1 MYPN NUTM1 PRKAB2 TRAF1 TRAF2 TRIM27 TRIM55 TRIM63 XIRP1 XIRP2 ZDHHC17 ZYX	7 interactors: ACTA1 ENAH EVL FLNC NEB NEBL VASP
Entrez ID		10529	165904
HPRD ID		10403	16727
Ensembl ID		ENSG00000078114	ENSG00000168334
Uniprot IDs		O76041 Q59FZ8	Q702N8
PDB IDs		4F14
Enriched GO Terms of Interacting Partners?		Actin Filament-based Process Cellular Component Assembly Actin Cytoskeleton Organization Cytoskeleton Organization Cell-cell Junction Organization Organelle Organization Adherens Junction Organization Actomyosin Structure Organization Focal Adhesion Assembly Cell-matrix Adhesion Protein K63-linked Ubiquitination Protein Trimerization Cell Junction Assembly Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell-substrate Adhesion Adherens Junction Assembly Signal Transduction Cell-substrate Junction Assembly Sarcomere Organization Regulation Of Metaphase Plate Congression Actin Filament Bundle Assembly Signaling Cell Communication Actin Filament Organization Negative Regulation Of Interleukin-2 Secretion Myofibril Assembly Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Protein Localization To Tight Junction Cellular Process Positive Regulation Of NF-kappaB Transcription Factor Activity See more	Actin Filament-based Process Actin Filament Organization Actin Cytoskeleton Organization Cell Development Actin Polymerization Or Depolymerization Cytoskeleton Organization Muscle Structure Development Striated Muscle Cell Development Muscle Cell Development Anatomical Structure Development Movement Of Cell Or Subcellular Component Regulation Of Actin Filament Length Striated Muscle Cell Differentiation Muscle Filament Sliding Actin-myosin Filament Sliding Developmental Process Cell Differentiation Cellular Component Assembly Actin-mediated Cell Contraction Muscle Cell Differentiation Regulation Of Cellular Component Size Muscle Fiber Development Regulation Of Actin Cytoskeleton Organization Anatomical Structure Formation Involved In Morphogenesis Actin Filament-based Movement Axon Guidance Protein Homotetramerization Regulation Of Actin Filament-based Process System Development Anatomical Structure Morphogenesis Myofibril Assembly Cardiac Muscle Thin Filament Assembly Regulation Of Cytoskeleton Organization Axonogenesis Multicellular Organismal Development Protein Tetramerization Neural Tube Closure Positive Regulation Of Actin Filament Polymerization T Cell Receptor Signaling Pathway Axon Development Actomyosin Structure Organization Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Protein Polymerization Chemotaxis Skeletal Muscle Fiber Adaptation Neural Tube Formation Neuron Projection Morphogenesis Organelle Organization Antigen Receptor-mediated Signaling Pathway Embryonic Epithelial Tube Formation See more
Tagcloud ?		anatomical assumes bcc bccs binomial correction crnkl1 drivers exome genesis hot intermittent invex landscape lend melanomas mutational passengers patched permutation pick ptch1 sccs sequenced spots stat5b stringent uniform uniquely	0x 1x adamts13 aspm atp6v0a2 bioinformatic bl chickens col12a1 fowl grm5 interpretations jungle lrp2 obscn plau ppp1ca prkdc resequencing rnf168 sanger sl slv smyth stab2 ubc ubiquitinylation vitiliginous vitiligo
Tagcloud (Difference) ?		anatomical assumes bcc bccs binomial correction crnkl1 drivers exome genesis hot intermittent invex landscape lend melanomas mutational passengers patched permutation pick ptch1 sccs sequenced spots stat5b stringent uniform uniquely	0x 1x adamts13 aspm atp6v0a2 bioinformatic bl chickens col12a1 fowl grm5 interpretations jungle lrp2 obscn plau ppp1ca prkdc resequencing rnf168 sanger sl slv smyth stab2 ubc ubiquitinylation vitiliginous vitiligo
Tagcloud (Intersection) ?