CDX4 and PRKAB2

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid, two hybrid)

		CDX4	PRKAB2
Gene Name		caudal type homeobox 4	protein kinase, AMP-activated, beta 2 non-catalytic subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm Cytosol AMP-activated Protein Kinase Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription	AMP-activated Protein Kinase Activity Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Blood Vessel Development Transcription, DNA-templated Anterior/posterior Pattern Specification Positive Regulation Of Transcription From RNA Polymerase II Promoter Labyrinthine Layer Development	Energy Reserve Metabolic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Carnitine Shuttle Organelle Organization Mitochondrion Organization Cell Cycle Arrest Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Regulation Of Protein Kinase Activity Membrane Organization
Pathways			Organelle biogenesis and maintenance Integration of energy metabolism Metabolism of lipids and lipoproteins Regulation of Rheb GTPase activity by AMPK IRS-mediated signalling mTOR signalling Translocation of GLUT4 to the plasma membrane Import of palmitoyl-CoA into the mitochondrial matrix mTOR signalling IGF1R signaling cascade IRS-related events triggered by IGF1R Energy dependent regulation of mTOR by LKB1-AMPK PKB-mediated events PI3K Cascade Signaling by Insulin receptor Fatty acid, triacylglycerol, and ketone body metabolism Insulin receptor signalling cascade Regulation of AMPK activity via LKB1 IRS-related events Mitochondrial biogenesis IRS-mediated signalling Activation of PPARGC1A (PGC-1alpha) by phosphorylation Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) AMPK inhibits chREBP transcriptional activation activity PKB-mediated events PI3K Cascade
Drugs			Adenosine monophosphate
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CKS1B HOXA5 LMO1 LMO2 PITX1 PRKAA1 PRKAB2	70 interactors: ADAMTSL4 BANP BEND5 BLZF1 CALCOCO2 CASP6 CCDC33 CCDC36 CDX4 CREB3L1 CRX CSNK2B DAO DDIT4L DICER1 DST EPM2A FAM208B FDX1 FLNC GATA1 GATAD2B GET4 GNB2L1 GOLGA2 GRN IKZF1 IKZF3 KCTD5 KLF15 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LZTS2 MAGED1 MDFI MEOX2 NEBL PIAS2 PRDM14 PRKAA1 PRKAA2 PRKAG1 PRKAG2 PRKAG3 PSME3 PYGM RBPMS REL RHEBL1 RIMBP3 SPRY2 STX11 STX19 TADA2A TCF4 TP53BP2 TRAF2 TRIM10 UBXN11 YY1AP1 ZBTB32
Entrez ID		1046	5565
HPRD ID		02065	04117
Ensembl ID			ENSG00000131791
Uniprot IDs		O14627	O43741
PDB IDs			2F15 2V8Q 2V92 2V9J 2Y8L 2Y8Q 2Y94 2YA3 4EAI 4EAJ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Gene Expression Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Regulation Of Metabolic Process Cellular Response To Hormone Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Fatty Acid Biosynthetic Process Regulation Of Lipid Biosynthetic Process Cell Cycle Arrest Insulin Receptor Signaling Pathway Negative Regulation Of Glucose Import In Response To Insulin Stimulus Cell-cell Signaling Involved In Mammary Gland Development Branchiomeric Skeletal Muscle Development Regulation Of Protein Kinase Activity Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Response To Camptothecin Bronchiole Development Lung Goblet Cell Differentiation Regulation Of Myeloid Cell Differentiation Regulation Of Kinase Activity Cartilage Development Intestinal Epithelial Cell Maturation Transcription From RNA Polymerase II Promoter Cellular Response To Insulin Stimulus Negative Regulation Of Sphingolipid Biosynthetic Process Lobar Bronchus Development Myoblast Fate Commitment Regulation Of Cell Cycle Response To Hormone Connective Tissue Development Regulation Of Ceramide Biosynthetic Process Transcription, DNA-templated Carnitine Shuttle Positive Regulation Of Cholesterol Biosynthetic Process Cell Cycle Process Positive Regulation Of Cholesterol Metabolic Process Cellular Response To Ethanol Bronchus Development Trachea Cartilage Morphogenesis Regulation Of Protein Phosphorylation RNA Biosynthetic Process Regulation Of Transcription, DNA-templated	Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Arrest Transcription, DNA-templated Regulation Of Gene Expression RNA Biosynthetic Process Glycogen Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Glycolytic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Cell Cycle Energy Reserve Metabolic Process Regulation Of Cell Cycle Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Biosynthetic Process Cellular Macromolecule Biosynthetic Process Polysaccharide Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Organelle Organization Gene Expression Cell Cycle Process Positive Regulation Of Phosphorylation RNA Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Protein Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Signaling Fatty Acid Biosynthetic Process Cellular Process Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Signal Transduction Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Binding Regulation Of Metabolic Process Regulation Of Carbohydrate Metabolic Process Regulation Of Phosphorylation Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Cell Death
Tagcloud ?		alters auto caudal chip circuit coregulate deeper defects erythroid erythropoiesis explain facilitates hematopoiesis hox initiate insight lmo2 locus mesoderm posterior proceeds profiling program rescued sall4 seq spalt zebrafish
Tagcloud (Difference) ?		alters auto caudal chip circuit coregulate deeper defects erythroid erythropoiesis explain facilitates hematopoiesis hox initiate insight lmo2 locus mesoderm posterior proceeds profiling program rescued sall4 seq spalt zebrafish
Tagcloud (Intersection) ?