CDK8 and TOP1

  • Number of citations of the paper that reports this interaction (PMID 12549820)
  • 1
  • Data Source:
  • BioGRID (unspecified method)

CDK8

TOP1

Gene Name cyclin-dependent kinase 8 topoisomerase (DNA) I
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 29 interactors: BCL6 CCNC CCNH CDKN2B CTD CTDP1 ERCC3 ESR1 ESR2 HIST2H3C MAML1 MBP MED12 MED21 MED25 MED26 MED8 MED9 MYC NRIP1 POLR2A SGCG SMAD2 SMAD3 SMARCA4 SREBF1 SUZ12 TOP1 TP53 55 interactors: APAF1 APP ATM BARD1 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 GRWD1 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PPP2R2B PRB1 PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I
Entrez ID 1024 7150
HPRD ID 04422 00535
Ensembl ID ENSG00000132964 ENSG00000198900
Uniprot IDs P49336 P11387
PDB IDs 3RGF 4F6S 4F6U 4F6W 4F70 4F7J 4F7L 4F7N 4F7S 4G6L 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
absent  acetyltransferase  acetyltransferases  cbp  chromatography  competent  complex  contains  conventional  directed  elongation  form  histone  homolog  ii  importantly  interacts  nonphosphorylated  notably  pcaf  polymerase  purified  remodeling  rna  snf  srb  srb10  swi  yeast 
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
Tagcloud (Difference) ?
absent  acetyltransferase  acetyltransferases  cbp  chromatography  competent  complex  contains  conventional  directed  elongation  form  histone  homolog  ii  importantly  interacts  nonphosphorylated  notably  pcaf  polymerase  purified  remodeling  rna  snf  srb  srb10  swi  yeast 
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
Tagcloud (Intersection) ?