CDK8 and MYC

  • Number of citations of the paper that reports this interaction (PMID 11673469)
  • 56

CDK8

MYC

Gene Name cyclin-dependent kinase 8 v-myc avian myelocytomatosis viral oncogene homolog
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 29 interactors: BCL6 CCNC CCNH CDKN2B CTD CTDP1 ERCC3 ESR1 ESR2 HIST2H3C MAML1 MBP MED12 MED21 MED25 MED26 MED8 MED9 MYC NRIP1 POLR2A SGCG SMAD2 SMAD3 SMARCA4 SREBF1 SUZ12 TOP1 TP53 126 interactors: ACTL6A ATAD2 AXIN1 BCL2 BIN1 BRCA1 BRD3 BTRC CCNH CCNT1 CDC6 CDCA7L CDK1 CDK4 CDK6 CDK8 CDKN2A CEBPA CEBPB CEP57 CREB1 CREBBP CSNK2A1 CSNK2A2 DNMT3A EFNB1 ELF3 EP300 EP400 FBXO8 FBXW7 FBXW8 GCN1L1 GPX2 GSK3A GSK3B GTF2B GTF2F1 GTF2I HNRNPD HSP90AA1 HUWE1 ING4 KAT2A KAT2B KAT5 KDM1A KIAA1524 KIDINS220 KPNA2 LDOC1 MAP2K1 MAPK1 MAPK3 MAPK7 MAPK8 MAX MED1 MED12 MED14 MED16 MEN1 MINA MLH1 MOK MXD1 MXI1 MYCBP MYCBP2 NEK11 NFYB NFYC NMI NOTCH3 NUCB1 PAK2 PARP10 PFDN5 PLAU PML POLR2A PRDX1 PSMC3 RAF1 RB1 RBL1 RELA RUVBL1 SAP130 SF3B1 SKP1 SKP2 SMAD2 SMAD3 SMARCA2 SMARCA4 SMARCB1 SMARCC1 SNIP1 SNRNP70 SP1 SPAG9 SUPT3H TADA2A TAF1B TAF5 TAF9 TBP TFAP2A TFAP2B TIAM1 TONSL TP73 TRIM6 TRRAP TUBA1A TUBA1B TUBA3C TUBA4A TUBA8 UBB USP37 YEATS4 YY1 ZBTB17 ZNF281
Entrez ID 1024 4609
HPRD ID 04422 01818
Ensembl ID ENSG00000132964 ENSG00000136997
Uniprot IDs P49336 P01106
PDB IDs 3RGF 4F6S 4F6U 4F6W 4F70 4F7J 4F7L 4F7N 4F7S 4G6L 1A93 1EE4 1MV0 1NKP 2A93 2OR9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
absent  acetyltransferase  acetyltransferases  cbp  chromatography  competent  complex  contains  conventional  directed  elongation  form  histone  homolog  ii  importantly  interacts  nonphosphorylated  notably  pcaf  polymerase  purified  remodeling  rna  snf  srb  srb10  swi  yeast 
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  nmi  potentiate  recruitment  reveal  screen  stat  stat1  stat2  stat5  stat5b  stats  yeast 
Tagcloud (Difference) ?
absent  acetyltransferase  acetyltransferases  chromatography  competent  complex  contains  conventional  directed  elongation  form  histone  homolog  ii  importantly  nonphosphorylated  notably  pcaf  polymerase  purified  remodeling  rna  snf  srb  srb10  swi 
augment  augments  bait  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interestingly  intrinsic  lacks  nmi  potentiate  recruitment  reveal  screen  stat  stat1  stat2  stat5  stat5b  stats 
Tagcloud (Intersection) ?
cbp  interacts  yeast