ABI2 and KHDRBS1

Number of citations of the paper that reports this interaction (PMID 22745667)
1

Data Source:
BioGRID (unspecified method)

		ABI2	KHDRBS1
Gene Name		abl-interactor 2	KH domain containing, RNA binding, signal transduction associated 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Lamellipodium Filopodium SCAR Complex	Nucleus Nucleoplasm Cytoplasm Membrane Grb2-Sos Complex
	Molecular Function	DNA Binding Protein Binding Cytoskeletal Adaptor Activity SH3 Domain Binding Kinase Binding Ubiquitin Protein Ligase Binding Protein Complex Binding Rac GTPase Binding Proline-rich Region Binding	DNA Binding RNA Binding SH3/SH2 Adaptor Activity Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding Protein Complex Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Movement Of Cell Or Subcellular Component Cytoskeleton Organization Actin Polymerization Or Depolymerization Cell Migration Rac Protein Signal Transduction Peptidyl-tyrosine Phosphorylation Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	G2/M Transition Of Mitotic Cell Cycle Transcription, DNA-templated MRNA Processing Cell Cycle Arrest Signal Transduction Cell Surface Receptor Signaling Pathway Cell Proliferation Positive Regulation Of Signal Transduction Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Translational Initiation Regulation Of RNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus
Pathways		Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS		Butyrylcholinesterase levels ( 21862451) Subclinical atherosclerosis traits (other) ( 17903303)
Protein-Protein Interactions		57 interactors: ABL1 ADAM19 AES ARHGAP32 ARMC7 BLOC1S6 CCDC102B CCDC36 CCDC53 CCHCR1 CDK6 CRX DTNB EFS EGLN3 EIF3H ENAH GCC1 HGS HNRNPK HOMER3 IFT20 KHDRBS1 KIAA1217 KIFC3 KRT13 KRT15 KRT19 KRT20 KRT31 KRT33B LMO2 MRFAP1L1 MRPL44 NCK2 NUP62 PCM1 PIN1 PPIF PRAM1 PRKAA1 PRKAA2 PRR16 SDCBP SH3KBP1 SNAP23 STAM2 TFIP11 TRAF3IP1 TRIM32 TRIP6 VARS2 VASP VCL VPS37C WASF2 WIPF1	109 interactors: ABI2 ACTB AGO1 AHI1 AMPH APBB1 ARHGEF4 ARHGEF9 AZIN1 BAIAP2L1 BTK BZRAP1 CBL CD2AP CDK1 CIRBP CREB3L3 CREBBP CRK CRKL CSK DDX5 DHX9 DLG1 DLG2 DLG3 DLG4 DNMBP DOCK2 DOCK3 EFEMP1 EMG1 FGR FNBP4 FRK FYN GAS7 GPHN GRAP GRAP2 GRB2 HCK HNRNPK INSR ITK ITSN1 ITSN2 JAK3 KHDRBS3 LCK LYN MAPK1 MIA2 MPP6 MYO1C MYO7A NCF1 NCK1 NCK2 NCKIPSD NPHP1 OSTF1 PACSIN1 PIK3R1 PIK3R3 PLCG1 PLCG2 POT1 PPP1R13B PRMT1 PSTPIP1 PTBP2 PTK6 PTPN6 RALY RAPSN RASA1 RBFOX2 RBM7 RBMX RUSC2 SASH1 SCG5 SH3PXD2A SH3YL1 SKAP2 SMAD2 SMARCA2 SNX30 SNX9 SORBS1 SPATA13 SRC SSFA2 STAT3 STUB1 TBL1X TJP1 TNFSF11 TUBB3 U2AF2 UBA52 UBASH3B VAV1 WBP4 YES1 YTHDC1 ZBTB7A ZDHHC6
Entrez ID		10152	10657
HPRD ID		07338	03926
Ensembl ID		ENSG00000138443	ENSG00000121774
Uniprot IDs		E9PEZ7 Q9NYB9	Q07666
PDB IDs		2ED0 3P8C	2XA6 3QHE
Enriched GO Terms of Interacting Partners?		Intracellular Transport Organelle Organization Cell Projection Assembly Establishment Of Localization In Cell Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Movement Of Cell Or Subcellular Component Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Signal Transduction Response To Stimulus Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Cytoskeleton Organization Negative Regulation Of Signaling Cellular Localization Cellular Component Assembly Regulation Of Signal Transduction Cell Projection Morphogenesis Cellular Response To Stimulus Developmental Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Cell Part Morphogenesis Cell Cycle Arrest Cell Projection Organization Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Signaling Actin Cytoskeleton Organization System Development Actin Filament-based Process Anatomical Structure Development Signaling Intraciliary Transport Cell Morphogenesis Membrane Organization Generation Of Neurons Cell Communication Regulation Of Autophagy Enzyme Linked Receptor Protein Signaling Pathway Multicellular Organismal Development Protein Localization Protein Transport Neurogenesis Lamellipodium Assembly Signal Transduction Lamellipodium Organization Establishment Of Protein Localization Negative Regulation Of Cellular Senescence Microtubule-based Transport	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Fc Receptor Signaling Pathway Signaling Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Communication Peptidyl-tyrosine Autophosphorylation Innate Immune Response Signal Transduction Immune Response-regulating Signaling Pathway Immune Response Endocytosis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Locomotion Movement Of Cell Or Subcellular Component Cellular Response To Stimulus Positive Regulation Of Metabolic Process Cell Surface Receptor Signaling Pathway Defense Response Positive Regulation Of Immune Response Regulation Of Immune System Process Cellular Response To Peptide Hormone Stimulus Neurotrophin TRK Receptor Signaling Pathway Phagocytosis Cellular Response To Peptide Positive Regulation Of Immune System Process Neurotrophin Signaling Pathway Positive Regulation Of Signal Transduction Cellular Response To Growth Factor Stimulus Regulation Of Immune Response Epidermal Growth Factor Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Growth Factor Antigen Receptor-mediated Signaling Pathway Cell Differentiation Regulation Of Catalytic Activity Regulation Of Signal Transduction Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Component Organization Immune System Process Response To Stimulus Regulation Of Signaling Cell Projection Organization Intracellular Signal Transduction Cellular Response To Organic Substance Regulation Of Metabolic Process
Tagcloud ?		aba abscisic arabidopsis aux1 auxin axr4 crosstalk ein2 eir1 elongation ethylene eto1 formed2 genotyping germination insensitive insensitive2 operate overproducer1 pin pin2 positional resistant1 resistant4 responsiveness root root1 seed thaliana
Tagcloud (Difference) ?		aba abscisic arabidopsis aux1 auxin axr4 crosstalk ein2 eir1 elongation ethylene eto1 formed2 genotyping germination insensitive insensitive2 operate overproducer1 pin pin2 positional resistant1 resistant4 responsiveness root root1 seed thaliana
Tagcloud (Intersection) ?