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KHDRBS1 and AHI1
Number of citations of the paper that reports this interaction (PubMedID
22745667
)
76
Data Source:
BioGRID
(unspecified method)
KHDRBS1
AHI1
Description
KH RNA binding domain containing, signal transduction associated 1
Abelson helper integration site 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Protein-containing Complex
Grb2-Sos Complex
Cytoplasm
Centrosome
Centriole
Cytosol
Cytoskeleton
Cell-cell Junction
Adherens Junction
Cilium
MKS Complex
Ciliary Basal Body
Cell Projection
Anchoring Junction
Non-motile Cilium
Molecular Function
Nucleic Acid Binding
DNA Binding
RNA Binding
MRNA Binding
Protein Binding
Poly(A) Binding
Poly(U) RNA Binding
SH3 Domain Binding
Protein Domain Specific Binding
Signaling Adaptor Activity
SH2 Domain Binding
Identical Protein Binding
Protein-containing Complex Binding
Molecular Function Inhibitor Activity
Protein Tyrosine Kinase Binding
Protein Binding
Identical Protein Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Processing
Cell Surface Receptor Signaling Pathway
Spermatogenesis
Regulation Of Protein Stability
Regulation Of Apoptotic Process
Regulation Of RNA Splicing
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Translational Initiation
Regulation Of RNA Export From Nucleus
Positive Regulation Of RNA Export From Nucleus
Regulation Of MRNA Splicing, Via Spliceosome
T Cell Receptor Signaling Pathway
Regulation Of Cell Cycle
Morphogenesis Of A Polarized Epithelium
Heart Looping
Positive Regulation Of Receptor Internalization
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Central Nervous System Development
Intracellular Protein Localization
Retina Layer Formation
Vesicle-mediated Transport
Cell Projection Organization
Cell Differentiation
Positive Regulation Of Polarized Epithelial Cell Differentiation
Hindbrain Development
Cloaca Development
Photoreceptor Cell Outer Segment Organization
Pronephric Nephron Tubule Morphogenesis
Negative Regulation Of Apoptotic Process
Motile Cilium Assembly
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Behavior
Cilium Assembly
Specification Of Axis Polarity
Otic Vesicle Development
Pathways
PTK6 Regulates Proteins Involved in RNA Processing
Anchoring of the basal body to the plasma membrane
Drugs
Diseases
Joubert syndrome
GWAS
Body mass index (
26426971
)
Arthritis (juvenile idiopathic) (
33106285
)
Asthma (
34103634
32296059
)
Basophil percentage of white cells (
32888494
)
Granulocyte count (
27863252
)
Hodgkin's lymphoma (
29196614
)
Monocyte count (
27863252
32888494
)
Monocyte percentage of white cells (
32888494
)
Multiple sclerosis (
24076602
21833088
)
Myeloid white cell count (
27863252
)
Neutrophil count (
32888494
27863252
)
Nodular sclerosis Hodgkin lymphoma (
29196614
)
Platelet distribution width (
32888494
)
Plateletcrit (
32888494
)
Selective IgA deficiency (
27723758
)
Serum omega-3 polyunsaturated fatty acid concentration in metabolic syndrome (
31991592
)
Sum basophil neutrophil counts (
27863252
)
Sum neutrophil eosinophil counts (
27863252
)
Systemic lupus erythematosus (
28714469
27399966
26502338
)
White blood cell count (
27863252
32888494
)
Interacting Genes
116 interacting genes:
ABI2
ACTB
AGO1
AHI1
AMPH
APBB1
ARHGEF4
ARHGEF9
AZIN1
BAIAP2L1
BTK
CBL
CD2AP
CDC42
CDK1
CEBPA
CIRBP
CLK1
CREB3L3
CREBBP
CRK
CRKL
CSK
DDX5
DHX9
DLG1
DLG2
DLG3
DLG4
DNMBP
DOCK2
DOCK3
DSCAM
EFEMP1
EMG1
FGR
FNBP4
FRK
FXR1
FXR2
FYN
GAS7
GPHN
GRAP
GRAP2
GRB2
HCK
HNRNPK
INSR
ITK
ITPRID2
ITSN1
ITSN2
JAK3
KHDRBS3
LCK
LYN
MAPK1
MYO1C
MYO7A
NCF1
NCK1
NCK2
NCKIPSD
NPHP1
OGT
OSTF1
PACSIN1
PALS2
PIK3R1
PIK3R3
PLCG1
PLCG2
POT1
PPP1R13B
PRMT1
PSTPIP1
PTBP2
PTK6
PTPN6
RALY
RAPSN
RASA1
RBFOX2
RBM7
RUSC2
SASH1
SCG5
SH3PXD2A
SH3YL1
SHANK3
SKAP2
SMAD2
SMARCA2
SNX30
SNX9
SORBS1
SPATA13
SRC
SRPK2
STAT3
STUB1
TBL1X
TJP1
TSPOAP1
TUBB3
UBA52
UBASH3B
UBC
USP7
VAV1
WBP4
YES1
YTHDC1
ZBTB7A
ZDHHC6
2 interacting genes:
KHDRBS1
VHL
Entrez ID
10657
54806
HPRD ID
03926
10597
Ensembl ID
ENSG00000121774
ENSG00000135541
Uniprot IDs
Q07666
A0A7P0T7Z8
A0A7P0T959
A0A7P0T9M6
A0A7P0T9Q2
Q8N157
Q8NER0
PDB IDs
2XA6
3QHE
7Z89
7Z8A
7Z9A
7Z9B
7ZAB
7ZAC
7ZAF
7ZAM
4ESR
Enriched GO Terms of Interacting Partners
?
Phosphotyrosine Residue Binding
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme-linked Receptor Protein Signaling Pathway
Non-membrane Spanning Protein Tyrosine Kinase Activity
Cytosol
Cytoplasm
Intracellular Signal Transduction
Immune Response-activating Cell Surface Receptor Signaling Pathway
Peptidyl-tyrosine Phosphorylation
Cell-cell Junction
Signal Transduction
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
Protein Tyrosine Kinase Activity
Immune Response-activating Signaling Pathway
Positive Regulation Of Cellular Component Organization
Regulation Of Cellular Component Organization
Fc Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
SH3 Domain Binding
Protein Binding
Activation Of Immune Response
Regulation Of Intracellular Signal Transduction
Antigen Receptor-mediated Signaling Pathway
Plasma Membrane
Regulation Of Signaling
Regulation Of Cell Communication
Regulation Of Signal Transduction
T Cell Receptor Signaling Pathway
T Cell Costimulation
Regulation Of Endocytosis
Fc-gamma Receptor Signaling Pathway
Intracellular Signaling Cassette
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Phosphorylation
Regulation Of Transport
Protein Phosphorylation
Fc Receptor Mediated Stimulatory Signaling Pathway
Ephrin Receptor Binding
Positive Regulation Of Immune Response
Regulation Of Immune System Process
Positive Regulation Of Immune System Process
Regulation Of Vesicle-mediated Transport
Developmental Process
Regulation Of Immune Response
Immune System Process
Ionotropic Glutamate Receptor Binding
Endocytosis
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Ephrin Receptor Signaling Pathway
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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