KHDRBS1 and AHI1

Number of citations of the paper that reports this interaction (PMID 22745667)
1

Data Source:
BioGRID (unspecified method)

		KHDRBS1	AHI1
Gene Name		KH domain containing, RNA binding, signal transduction associated 1	Abelson helper integration site 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Grb2-Sos Complex	Photoreceptor Outer Segment Centrosome Centriole Cell-cell Junction Adherens Junction Cilium Nonmotile Primary Cilium TCTN-B9D Complex Ciliary Basal Body Primary Cilium
	Molecular Function	DNA Binding RNA Binding SH3/SH2 Adaptor Activity Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding Protein Complex Binding Identical Protein Binding Poly(A) RNA Binding	Protein Binding Identical Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Transcription, DNA-templated MRNA Processing Cell Cycle Arrest Signal Transduction Cell Surface Receptor Signaling Pathway Cell Proliferation Positive Regulation Of Signal Transduction Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Translational Initiation Regulation Of RNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus	Morphogenesis Of A Polarized Epithelium Heart Looping Positive Regulation Of Receptor Internalization Vesicle Targeting Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Central Nervous System Development Retina Layer Formation Vesicle-mediated Transport Positive Regulation Of Polarized Epithelial Cell Differentiation Hindbrain Development Protein Localization To Organelle Cellular Protein Localization Cloaca Development Photoreceptor Cell Outer Segment Organization Pronephric Nephron Tubule Morphogenesis Pronephric Duct Morphogenesis Cilium Assembly Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Behavior Cilium Morphogenesis Specification Of Axis Polarity Kupffer's Vesicle Development Left/right Axis Specification Otic Vesicle Development
Pathways
Drugs
Diseases
GWAS			Multiple sclerosis ( 21833088)
Protein-Protein Interactions		109 interactors: ABI2 ACTB AGO1 AHI1 AMPH APBB1 ARHGEF4 ARHGEF9 AZIN1 BAIAP2L1 BTK BZRAP1 CBL CD2AP CDK1 CIRBP CREB3L3 CREBBP CRK CRKL CSK DDX5 DHX9 DLG1 DLG2 DLG3 DLG4 DNMBP DOCK2 DOCK3 EFEMP1 EMG1 FGR FNBP4 FRK FYN GAS7 GPHN GRAP GRAP2 GRB2 HCK HNRNPK INSR ITK ITSN1 ITSN2 JAK3 KHDRBS3 LCK LYN MAPK1 MIA2 MPP6 MYO1C MYO7A NCF1 NCK1 NCK2 NCKIPSD NPHP1 OSTF1 PACSIN1 PIK3R1 PIK3R3 PLCG1 PLCG2 POT1 PPP1R13B PRMT1 PSTPIP1 PTBP2 PTK6 PTPN6 RALY RAPSN RASA1 RBFOX2 RBM7 RBMX RUSC2 SASH1 SCG5 SH3PXD2A SH3YL1 SKAP2 SMAD2 SMARCA2 SNX30 SNX9 SORBS1 SPATA13 SRC SSFA2 STAT3 STUB1 TBL1X TJP1 TNFSF11 TUBB3 U2AF2 UBA52 UBASH3B VAV1 WBP4 YES1 YTHDC1 ZBTB7A ZDHHC6	1 interactors: KHDRBS1
Entrez ID		10657	54806
HPRD ID		03926	10597
Ensembl ID		ENSG00000121774	ENSG00000135541
Uniprot IDs		Q07666	Q8N157 Q8NER0
PDB IDs		2XA6 3QHE	4ESR
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Fc Receptor Signaling Pathway Signaling Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Communication Peptidyl-tyrosine Autophosphorylation Innate Immune Response Signal Transduction Immune Response-regulating Signaling Pathway Immune Response Endocytosis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Locomotion Movement Of Cell Or Subcellular Component Cellular Response To Stimulus Positive Regulation Of Metabolic Process Cell Surface Receptor Signaling Pathway Defense Response Positive Regulation Of Immune Response Regulation Of Immune System Process Cellular Response To Peptide Hormone Stimulus Neurotrophin TRK Receptor Signaling Pathway Phagocytosis Cellular Response To Peptide Positive Regulation Of Immune System Process Neurotrophin Signaling Pathway Positive Regulation Of Signal Transduction Cellular Response To Growth Factor Stimulus Regulation Of Immune Response Epidermal Growth Factor Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Growth Factor Antigen Receptor-mediated Signaling Pathway Cell Differentiation Regulation Of Catalytic Activity Regulation Of Signal Transduction Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Component Organization Immune System Process Response To Stimulus Regulation Of Signaling Cell Projection Organization Intracellular Signal Transduction Cellular Response To Organic Substance Regulation Of Metabolic Process	Positive Regulation Of RNA Export From Nucleus Regulation Of RNA Export From Nucleus Positive Regulation Of Translational Initiation Regulation Of Translational Initiation Positive Regulation Of Translation
Tagcloud ?			applies arg1066 carriership categorization ciliopathy consanguineous deafness dispensable erroneous glu984 homozygosity homozygotes impairing jbts joubert kingsmore morpholinos orthologous positives preconception ruled syndromic trp1088 trp1088leufs truncating unambiguous unmask wd40 wes
Tagcloud (Difference) ?			applies arg1066 carriership categorization ciliopathy consanguineous deafness dispensable erroneous glu984 homozygosity homozygotes impairing jbts joubert kingsmore morpholinos orthologous positives preconception ruled syndromic trp1088 trp1088leufs truncating unambiguous unmask wd40 wes
Tagcloud (Intersection) ?