KHDRBS1 and MYO1C

Number of citations of the paper that reports this interaction (PMID 22745667)
1

Data Source:
BioGRID (unspecified method)

		KHDRBS1	MYO1C
Gene Name		KH domain containing, RNA binding, signal transduction associated 1	myosin IC
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Grb2-Sos Complex	Stress Fiber Ruffle Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Mitochondrion Cytosol Plasma Membrane Microvillus Brush Border Basal Plasma Membrane Membrane Cytoplasmic Membrane-bounded Vesicle Lateral Plasma Membrane Unconventional Myosin Complex Filamentous Actin Membrane Raft Myosin I Complex Stereocilium Membrane Extracellular Vesicular Exosome
	Molecular Function	DNA Binding RNA Binding SH3/SH2 Adaptor Activity Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding Protein Complex Binding Identical Protein Binding Poly(A) RNA Binding	Motor Activity Actin Binding Receptor Binding Protein Binding Calmodulin Binding ATP Binding Protein C-terminus Binding Ral GTPase Binding Actin-dependent ATPase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Transcription, DNA-templated MRNA Processing Cell Cycle Arrest Signal Transduction Cell Surface Receptor Signaling Pathway Cell Proliferation Positive Regulation Of Signal Transduction Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Translational Initiation Regulation Of RNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus	Protein Targeting Protein Targeting To Membrane Positive Regulation Of Cell Migration Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response MRNA Transport Membrane Organization Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Tight Junction Assembly
Pathways			Translocation of GLUT4 to the plasma membrane Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		109 interactors: ABI2 ACTB AGO1 AHI1 AMPH APBB1 ARHGEF4 ARHGEF9 AZIN1 BAIAP2L1 BTK BZRAP1 CBL CD2AP CDK1 CIRBP CREB3L3 CREBBP CRK CRKL CSK DDX5 DHX9 DLG1 DLG2 DLG3 DLG4 DNMBP DOCK2 DOCK3 EFEMP1 EMG1 FGR FNBP4 FRK FYN GAS7 GPHN GRAP GRAP2 GRB2 HCK HNRNPK INSR ITK ITSN1 ITSN2 JAK3 KHDRBS3 LCK LYN MAPK1 MIA2 MPP6 MYO1C MYO7A NCF1 NCK1 NCK2 NCKIPSD NPHP1 OSTF1 PACSIN1 PIK3R1 PIK3R3 PLCG1 PLCG2 POT1 PPP1R13B PRMT1 PSTPIP1 PTBP2 PTK6 PTPN6 RALY RAPSN RASA1 RBFOX2 RBM7 RBMX RUSC2 SASH1 SCG5 SH3PXD2A SH3YL1 SKAP2 SMAD2 SMARCA2 SNX30 SNX9 SORBS1 SPATA13 SRC SSFA2 STAT3 STUB1 TBL1X TJP1 TNFSF11 TUBB3 U2AF2 UBA52 UBASH3B VAV1 WBP4 YES1 YTHDC1 ZBTB7A ZDHHC6	4 interactors: BAZ1B CBL KHDRBS1 RRN3
Entrez ID		10657	4641
HPRD ID		03926	09411
Ensembl ID		ENSG00000121774	ENSG00000197879
Uniprot IDs		Q07666	F5H6E2 O00159
PDB IDs		2XA6 3QHE
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Fc Receptor Signaling Pathway Signaling Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Communication Peptidyl-tyrosine Autophosphorylation Innate Immune Response Signal Transduction Immune Response-regulating Signaling Pathway Immune Response Endocytosis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Locomotion Movement Of Cell Or Subcellular Component Cellular Response To Stimulus Positive Regulation Of Metabolic Process Cell Surface Receptor Signaling Pathway Defense Response Positive Regulation Of Immune Response Regulation Of Immune System Process Cellular Response To Peptide Hormone Stimulus Neurotrophin TRK Receptor Signaling Pathway Phagocytosis Cellular Response To Peptide Positive Regulation Of Immune System Process Neurotrophin Signaling Pathway Positive Regulation Of Signal Transduction Cellular Response To Growth Factor Stimulus Regulation Of Immune Response Epidermal Growth Factor Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Growth Factor Antigen Receptor-mediated Signaling Pathway Cell Differentiation Regulation Of Catalytic Activity Regulation Of Signal Transduction Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Component Organization Immune System Process Response To Stimulus Regulation Of Signaling Cell Projection Organization Intracellular Signal Transduction Cellular Response To Organic Substance Regulation Of Metabolic Process	Regulation Of Signal Transduction Regulation Of Signaling Positive Regulation Of RNA Export From Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Nucleolus Organization Cytoplasm Organization Regulation Of RNA Metabolic Process Chromatin-mediated Maintenance Of Transcription Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Export From Nucleus Positive Regulation Of Translational Initiation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Gene Expression, Epigenetic Transcription, DNA-templated Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of DNA-templated Transcription, Initiation RNA Biosynthetic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Transcription Initiation From RNA Polymerase I Promoter Positive Regulation Of Cellular Metabolic Process Cell Proliferation Transcription From RNA Polymerase I Promoter Positive Regulation Of Transport Positive Regulation Of Receptor-mediated Endocytosis Histone Phosphorylation Positive Regulation Of Receptor Activity Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death RNA Metabolic Process Negative Regulation Of Cell Death Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Signal Transduction Regulation Of Translational Initiation Cellular Macromolecule Biosynthetic Process Positive Regulation Of Translation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Macromolecule Biosynthetic Process Regulation Of ERBB Signaling Pathway
Tagcloud ?			actin attenuates blocked cargo cooperatively cytoskeletal deletion diminished dominant essential ikappab ikk intact interaction irs lacking modulator motor necrosis nemo network phosphorylates precise requires ruffles ser307 silencing tnf trafficking
Tagcloud (Difference) ?			actin attenuates blocked cargo cooperatively cytoskeletal deletion diminished dominant essential ikappab ikk intact interaction irs lacking modulator motor necrosis nemo network phosphorylates precise requires ruffles ser307 silencing tnf trafficking
Tagcloud (Intersection) ?