ABI2 and ARMC7

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ABI2	ARMC7
Gene Name		abl-interactor 2	armadillo repeat containing 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Lamellipodium Filopodium SCAR Complex	Nucleus Cytoplasm
	Molecular Function	DNA Binding Protein Binding Cytoskeletal Adaptor Activity SH3 Domain Binding Kinase Binding Ubiquitin Protein Ligase Binding Protein Complex Binding Rac GTPase Binding Proline-rich Region Binding
	Biological Process	Movement Of Cell Or Subcellular Component Cytoskeleton Organization Actin Polymerization Or Depolymerization Cell Migration Rac Protein Signal Transduction Peptidyl-tyrosine Phosphorylation Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways		Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS		Butyrylcholinesterase levels ( 21862451) Subclinical atherosclerosis traits (other) ( 17903303)
Protein-Protein Interactions		57 interactors: ABL1 ADAM19 AES ARHGAP32 ARMC7 BLOC1S6 CCDC102B CCDC36 CCDC53 CCHCR1 CDK6 CRX DTNB EFS EGLN3 EIF3H ENAH GCC1 HGS HNRNPK HOMER3 IFT20 KHDRBS1 KIAA1217 KIFC3 KRT13 KRT15 KRT19 KRT20 KRT31 KRT33B LMO2 MRFAP1L1 MRPL44 NCK2 NUP62 PCM1 PIN1 PPIF PRAM1 PRKAA1 PRKAA2 PRR16 SDCBP SH3KBP1 SNAP23 STAM2 TFIP11 TRAF3IP1 TRIM32 TRIP6 VARS2 VASP VCL VPS37C WASF2 WIPF1	23 interactors: ABI2 ABI3 APP C2orf88 CCDC33 CPSF6 CPSF7 EFHC2 IKZF1 IKZF3 INCA1 KCTD13 KRT31 KRT40 LZTS2 PAK7 RUNDC3A SPATC1L SPERT TCF4 TNFAIP1 TRIM27 TRIM42
Entrez ID		10152	79637
HPRD ID		07338	08649
Ensembl ID		ENSG00000138443	ENSG00000125449
Uniprot IDs		E9PEZ7 Q9NYB9	B4DVA4 Q9H6L4
PDB IDs		2ED0 3P8C
Enriched GO Terms of Interacting Partners?		Intracellular Transport Organelle Organization Cell Projection Assembly Establishment Of Localization In Cell Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Movement Of Cell Or Subcellular Component Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Signal Transduction Response To Stimulus Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Cytoskeleton Organization Negative Regulation Of Signaling Cellular Localization Cellular Component Assembly Regulation Of Signal Transduction Cell Projection Morphogenesis Cellular Response To Stimulus Developmental Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Cell Part Morphogenesis Cell Cycle Arrest Cell Projection Organization Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Signaling Actin Cytoskeleton Organization System Development Actin Filament-based Process Anatomical Structure Development Signaling Intraciliary Transport Cell Morphogenesis Membrane Organization Generation Of Neurons Cell Communication Regulation Of Autophagy Enzyme Linked Receptor Protein Signaling Pathway Multicellular Organismal Development Protein Localization Protein Transport Neurogenesis Lamellipodium Assembly Signal Transduction Lamellipodium Organization Establishment Of Protein Localization Negative Regulation Of Cellular Senescence Microtubule-based Transport	Protein Oligomerization Cellular Component Assembly MRNA 3'-end Processing Stress Fiber Assembly Actin Filament Organization Protein Complex Assembly RNA 3'-end Processing Cytoskeleton Organization Negative Regulation Of Rho Protein Signal Transduction MRNA Polyadenylation RNA Polyadenylation Movement Of Cell Or Subcellular Component Positive Regulation Of Cellular Biosynthetic Process Actin Cytoskeleton Organization Organelle Organization Negative Regulation Of Signal Transduction Positive Regulation Of Neutrophil Differentiation Learning Or Memory Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Actin Filament-based Process Positive Regulation Of DNA Replication Negative Regulation Of Signaling Regulation Of Developmental Growth Cognition Actin Filament Bundle Assembly Locomotion Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Nucleobase-containing Compound Metabolic Process Regulation Of Signal Transduction Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Collateral Sprouting In Absence Of Injury Regulation Of Multicellular Organism Growth Cell Migration Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Tetramerization Maintenance Of DNA Repeat Elements Actomyosin Structure Organization Positive Regulation Of Macromolecule Biosynthetic Process MRNA Processing Cell Motility Regulation Of Signaling Cellular Nitrogen Compound Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Forebrain Development
Tagcloud ?		aba abscisic arabidopsis aux1 auxin axr4 crosstalk ein2 eir1 elongation ethylene eto1 formed2 genotyping germination insensitive insensitive2 operate overproducer1 pin pin2 positional resistant1 resistant4 responsiveness root root1 seed thaliana
Tagcloud (Difference) ?		aba abscisic arabidopsis aux1 auxin axr4 crosstalk ein2 eir1 elongation ethylene eto1 formed2 genotyping germination insensitive insensitive2 operate overproducer1 pin pin2 positional resistant1 resistant4 responsiveness root root1 seed thaliana
Tagcloud (Intersection) ?