ABI2 and MRFAP1L1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ABI2	MRFAP1L1
Gene Name		abl-interactor 2	Morf4 family associated protein 1-like 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Lamellipodium Filopodium SCAR Complex
	Molecular Function	DNA Binding Protein Binding Cytoskeletal Adaptor Activity SH3 Domain Binding Kinase Binding Ubiquitin Protein Ligase Binding Protein Complex Binding Rac GTPase Binding Proline-rich Region Binding	Protein Binding
	Biological Process	Movement Of Cell Or Subcellular Component Cytoskeleton Organization Actin Polymerization Or Depolymerization Cell Migration Rac Protein Signal Transduction Peptidyl-tyrosine Phosphorylation Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways		Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS		Butyrylcholinesterase levels ( 21862451) Subclinical atherosclerosis traits (other) ( 17903303)
Protein-Protein Interactions		57 interactors: ABL1 ADAM19 AES ARHGAP32 ARMC7 BLOC1S6 CCDC102B CCDC36 CCDC53 CCHCR1 CDK6 CRX DTNB EFS EGLN3 EIF3H ENAH GCC1 HGS HNRNPK HOMER3 IFT20 KHDRBS1 KIAA1217 KIFC3 KRT13 KRT15 KRT19 KRT20 KRT31 KRT33B LMO2 MRFAP1L1 MRPL44 NCK2 NUP62 PCM1 PIN1 PPIF PRAM1 PRKAA1 PRKAA2 PRR16 SDCBP SH3KBP1 SNAP23 STAM2 TFIP11 TRAF3IP1 TRIM32 TRIP6 VARS2 VASP VCL VPS37C WASF2 WIPF1	37 interactors: ABI2 ABI3 BYSL C3orf62 CAGE1 CCDC36 CDK2AP1 CDK2AP2 CENPK CEP44 CSPP1 EIF2B2 HGS HTT LMO2 LNX1 MEOX2 MORF4L1 MORF4L2 MRFAP1 PIH1D2 PIK3R2 PRKCDBP PSMA1 RADIL RDM1 SDCBP SFR1 SMARCE1 SMU1 SYCE1 TCF4 TMEM126B TSNAX TXN2 UBTD1 ZDHHC17
Entrez ID		10152	114932
HPRD ID		07338	15162
Ensembl ID		ENSG00000138443	ENSG00000178988
Uniprot IDs		E9PEZ7 Q9NYB9	Q96HT8
PDB IDs		2ED0 3P8C
Enriched GO Terms of Interacting Partners?		Intracellular Transport Organelle Organization Cell Projection Assembly Establishment Of Localization In Cell Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Movement Of Cell Or Subcellular Component Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Signal Transduction Response To Stimulus Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Cytoskeleton Organization Negative Regulation Of Signaling Cellular Localization Cellular Component Assembly Regulation Of Signal Transduction Cell Projection Morphogenesis Cellular Response To Stimulus Developmental Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Cell Part Morphogenesis Cell Cycle Arrest Cell Projection Organization Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Signaling Actin Cytoskeleton Organization System Development Actin Filament-based Process Anatomical Structure Development Signaling Intraciliary Transport Cell Morphogenesis Membrane Organization Generation Of Neurons Cell Communication Regulation Of Autophagy Enzyme Linked Receptor Protein Signaling Pathway Multicellular Organismal Development Protein Localization Protein Transport Neurogenesis Lamellipodium Assembly Signal Transduction Lamellipodium Organization Establishment Of Protein Localization Negative Regulation Of Cellular Senescence Microtubule-based Transport	Positive Regulation Of Metabolic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Response To Glucose Cellular Response To Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Chromosome Organization Negative Regulation Of Organ Growth DNA Metabolic Process Oligodendrocyte Development Neural Plate Formation Negative Regulation Of Fermentation Response To Carbohydrate Protein Targeting Cellular Response To Stress Positive Regulation Of Transport Organelle Organization
Tagcloud ?		aba abscisic arabidopsis aux1 auxin axr4 crosstalk ein2 eir1 elongation ethylene eto1 formed2 genotyping germination insensitive insensitive2 operate overproducer1 pin pin2 positional resistant1 resistant4 responsiveness root root1 seed thaliana
Tagcloud (Difference) ?		aba abscisic arabidopsis aux1 auxin axr4 crosstalk ein2 eir1 elongation ethylene eto1 formed2 genotyping germination insensitive insensitive2 operate overproducer1 pin pin2 positional resistant1 resistant4 responsiveness root root1 seed thaliana
Tagcloud (Intersection) ?