KHDRBS1 and BAIAP2L1

Number of citations of the paper that reports this interaction (PubMedID 22745667)
76

Data Source:
BioGRID (unspecified method)

		KHDRBS1	BAIAP2L1
Description		KH RNA binding domain containing, signal transduction associated 1	BAR/IMD domain containing adaptor protein 2 like 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Protein-containing Complex Grb2-Sos Complex	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Actin Cytoskeleton Extracellular Exosome
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding MRNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding Protein Domain Specific Binding Signaling Adaptor Activity SH2 Domain Binding Identical Protein Binding Protein-containing Complex Binding Molecular Function Inhibitor Activity Protein Tyrosine Kinase Binding	Actin Binding Protein Binding Proline-rich Region Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	G1/S Transition Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Cell Surface Receptor Signaling Pathway Spermatogenesis Regulation Of Protein Stability Regulation Of Apoptotic Process Regulation Of RNA Splicing Negative Regulation Of DNA-templated Transcription Positive Regulation Of Translational Initiation Regulation Of RNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus Regulation Of MRNA Splicing, Via Spliceosome T Cell Receptor Signaling Pathway Regulation Of Cell Cycle	Plasma Membrane Organization Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Regulation Of Actin Cytoskeleton Organization Actin Filament Bundle Assembly Actin Crosslink Formation Cell-cell Adhesion
Pathways		PTK6 Regulates Proteins Involved in RNA Processing	RAC1 GTPase cycle RAC2 GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Apolipoprotein B levels ( 32203549) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Pursuit maintenance gain ( 29064472) Sex hormone-binding globulin levels ( 22829776) White blood cell count ( 32888494)
Interacting Genes		116 interacting genes: ABI2 ACTB AGO1 AHI1 AMPH APBB1 ARHGEF4 ARHGEF9 AZIN1 BAIAP2L1 BTK CBL CD2AP CDC42 CDK1 CEBPA CIRBP CLK1 CREB3L3 CREBBP CRK CRKL CSK DDX5 DHX9 DLG1 DLG2 DLG3 DLG4 DNMBP DOCK2 DOCK3 DSCAM EFEMP1 EMG1 FGR FNBP4 FRK FXR1 FXR2 FYN GAS7 GPHN GRAP GRAP2 GRB2 HCK HNRNPK INSR ITK ITPRID2 ITSN1 ITSN2 JAK3 KHDRBS3 LCK LYN MAPK1 MYO1C MYO7A NCF1 NCK1 NCK2 NCKIPSD NPHP1 OGT OSTF1 PACSIN1 PALS2 PIK3R1 PIK3R3 PLCG1 PLCG2 POT1 PPP1R13B PRMT1 PSTPIP1 PTBP2 PTK6 PTPN6 RALY RAPSN RASA1 RBFOX2 RBM7 RUSC2 SASH1 SCG5 SH3PXD2A SH3YL1 SHANK3 SKAP2 SMAD2 SMARCA2 SNX30 SNX9 SORBS1 SPATA13 SRC SRPK2 STAT3 STUB1 TBL1X TJP1 TSPOAP1 TUBB3 UBA52 UBASH3B UBC USP7 VAV1 WBP4 YES1 YTHDC1 ZBTB7A ZDHHC6	10 interacting genes: BAG3 CYSRT1 FASLG KHDRBS1 LANCL1 MDM2 NEDD4 TP53 WAS YWHAG
Entrez ID		10657	55971
HPRD ID		03926	11270
Ensembl ID		ENSG00000121774	ENSG00000006453
Uniprot IDs		Q07666	Q9UHR4
PDB IDs		2XA6 3QHE 7Z89 7Z8A 7Z9A 7Z9B 7ZAB 7ZAC 7ZAF 7ZAM	2KXC 2LNH
Enriched GO Terms of Interacting Partners?		Phosphotyrosine Residue Binding Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Non-membrane Spanning Protein Tyrosine Kinase Activity Cytosol Cytoplasm Intracellular Signal Transduction Immune Response-activating Cell Surface Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Cell-cell Junction Signal Transduction Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Protein Tyrosine Kinase Activity Immune Response-activating Signaling Pathway Positive Regulation Of Cellular Component Organization Regulation Of Cellular Component Organization Fc Receptor Signaling Pathway Immune Response-regulating Signaling Pathway SH3 Domain Binding Protein Binding Activation Of Immune Response Regulation Of Intracellular Signal Transduction Antigen Receptor-mediated Signaling Pathway Plasma Membrane Regulation Of Signaling Regulation Of Cell Communication Regulation Of Signal Transduction T Cell Receptor Signaling Pathway T Cell Costimulation Regulation Of Endocytosis Fc-gamma Receptor Signaling Pathway Intracellular Signaling Cassette Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Phosphorylation Regulation Of Transport Protein Phosphorylation Fc Receptor Mediated Stimulatory Signaling Pathway Ephrin Receptor Binding Positive Regulation Of Immune Response Regulation Of Immune System Process Positive Regulation Of Immune System Process Regulation Of Vesicle-mediated Transport Developmental Process Regulation Of Immune Response Immune System Process Ionotropic Glutamate Receptor Binding Endocytosis Negative Regulation Of Inflammatory Response To Antigenic Stimulus Ephrin Receptor Signaling Pathway	Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Intracellular Transport Regulation Of Protein Stability Regulation Of Nucleocytoplasmic Transport Cellular Response To Actinomycin D Response To Actinomycin D Cellular Response To UV-C Protein Domain Specific Binding Regulation Of Biological Quality Regulation Of Intracellular Transport Cellular Response To Antibiotic Cellular Response To UV Signal Transduction Necroptotic Process Cellular Response To Light Stimulus Response To UV-C Striated Muscle Cell Apoptotic Process SH3 Domain Binding Positive Regulation Of Transport Muscle Cell Apoptotic Process Positive Regulation Of Protein Export From Nucleus Programmed Necrotic Cell Death Response To UV Disordered Domain Specific Binding Negative Regulation Of Transcription By RNA Polymerase II Cellular Response To Gamma Radiation Cellular Response To Radiation T Cell Apoptotic Process Regulation Of Cellular Localization Regulation Of Macroautophagy Identical Protein Binding Lymphocyte Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Antibiotic Regulation Of Protein Export From Nucleus Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Protein Stabilization Leukocyte Apoptotic Process Protein Localization To Organelle DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Translational Initiation Cellular Response To Nutrient Levels Cell Activation Cellular Response To Glucose Starvation Establishment Of Protein Localization Response To Gamma Radiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Polyubiquitination
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