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ACTR2 and CTTN
Number of citations of the paper that reports this interaction (PMID
11018051
)
94
Data Source:
BioGRID
(affinity chromatography technology, pull down)
ACTR2
CTTN
Gene Name
ARP2 actin-related protein 2 homolog (yeast)
cortactin
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Arp2/3 Protein Complex
Focal Adhesion
Actin Cytoskeleton
Membrane
Actin Cap
Cell Projection
Extracellular Vesicular Exosome
Ruffle
Cytoplasm
Cytoskeleton
Actin Filament
Coated Pit
Focal Adhesion
Cell Cortex
Voltage-gated Potassium Channel Complex
Lamellipodium
Growth Cone
Cortical Cytoskeleton
Dendritic Spine
Extracellular Vesicular Exosome
Mitotic Spindle Midzone
Molecular Function
Structural Constituent Of Cytoskeleton
ATP Binding
Actin Filament Binding
Protein Binding
Biological Process
Movement Of Cell Or Subcellular Component
Establishment Or Maintenance Of Cell Polarity
Axon Guidance
Asymmetric Cell Division
Meiotic Chromosome Movement Towards Spindle Pole
Cytoplasmic Transport
Meiotic Cytokinesis
Arp2/3 Complex-mediated Actin Nucleation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Cilium Assembly
Innate Immune Response
Ephrin Receptor Signaling Pathway
Spindle Localization
Intracellular Protein Transport
Receptor-mediated Endocytosis
Substrate-dependent Cell Migration, Cell Extension
Actin Filament Polymerization
Regulation Of Axon Extension
Positive Regulation Of Actin Filament Polymerization
Actin Cytoskeleton Reorganization
Focal Adhesion Assembly
Neuron Projection Morphogenesis
Cell Motility
Dendritic Spine Maintenance
Lamellipodium Organization
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
EPHB-mediated forward signaling
Axon guidance
EPH-Ephrin signaling
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
13 interactors:
ACTC1
ACTR3
ARPC1B
ARPC4
ARPC5
BMP2
CTTN
ELF5
HCLS1
IQGAP2
WASF1
WASF2
WASL
36 interactors:
ACD
ACTA1
ACTG1
ACTR2
ACTR3
ANKZF1
ARHGAP17
ARHGAP8
CASP3
CD2AP
CHD3
CTNND1
CTNND2
CTTNBP2
DNM1
DNM2
FER
FGD1
GRB2
HAX1
HDAC6
HIP1R
KCNA2
MET
MYLK
SDC3
SHANK2
SIRT1
SPRR2A
SRC
SYK
TINF2
TJP1
TNK2
WASL
WIPF1
Entrez ID
10097
2017
HPRD ID
05023
01268
Ensembl ID
ENSG00000138071
ENSG00000085733
Uniprot IDs
P61160
Q14247
Q53HG7
PDB IDs
1X69
2D1X
Enriched GO Terms of Interacting Partners
?
Actin Filament Organization
Positive Regulation Of Cytoskeleton Organization
Regulation Of Actin Cytoskeleton Organization
Actin Cytoskeleton Organization
Actin Filament-based Process
Regulation Of Actin Filament-based Process
Regulation Of Cytoskeleton Organization
Positive Regulation Of Organelle Organization
Cytoskeleton Organization
Positive Regulation Of Cellular Component Biogenesis
Regulation Of Actin Filament Polymerization
Regulation Of Organelle Organization
Arp2/3 Complex-mediated Actin Nucleation
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Protein Polymerization
Actin Nucleation
Regulation Of Cellular Component Organization
Regulation Of Cellular Component Size
Regulation Of Protein Complex Assembly
Positive Regulation Of Protein Complex Assembly
Actin Polymerization Or Depolymerization
Actin Filament Polymerization
Movement Of Cell Or Subcellular Component
Organelle Organization
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Phagocytosis
Ephrin Receptor Signaling Pathway
Protein Polymerization
Fc Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Cell Morphogenesis
Endocytosis
Cell Differentiation
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Development
Cell Projection Morphogenesis
Cell Part Morphogenesis
Immune Response-regulating Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Immune System Process
System Development
Actin Filament-based Movement
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Positive Regulation Of Actin Nucleation
Anatomical Structure Morphogenesis
Positive Regulation Of Immune Response
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Anatomical Structure Morphogenesis
Enzyme Linked Receptor Protein Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Endocytosis
Fc Receptor Signaling Pathway
Cellular Response To Stimulus
Cellular Component Assembly
Regulation Of Cellular Component Organization
Actin Cytoskeleton Organization
Actin Filament-based Process
Anatomical Structure Development
Response To External Stimulus
Developmental Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Organelle Organization
Phagocytosis
Cell Communication
Positive Regulation Of Organelle Organization
Multicellular Organismal Development
Immune Response-activating Cell Surface Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Organelle Organization
Movement Of Cell Or Subcellular Component
Chemotaxis
Immune Response-regulating Signaling Pathway
System Development
Signaling
Cytoskeleton Organization
Signal Transduction
Positive Regulation Of Immune System Process
Response To Stimulus
Cell Projection Organization
Cell Morphogenesis Involved In Differentiation
Axon Guidance
Locomotion
Innate Immune Response
Positive Regulation Of Protein Complex Assembly
Regulation Of Immune System Process
Cell Morphogenesis
Actin Filament Organization
Positive Regulation Of Immune Response
Neuron Projection Morphogenesis
Positive Regulation Of Cellular Component Biogenesis
Regulation Of Immune Response
Peptidyl-tyrosine Autophosphorylation
Regulation Of Protein Complex Assembly
Positive Regulation Of Cytoskeleton Organization
Tagcloud
?
applicability
csmd1
delineate
emphasized
fadd
fgf4
fhit
floor
gains
gata4
imbalances
individualized
losses
mandatory
mccc1
mlpa
mouth
mtus1
multiplex
p428
panel
probe
probemix
propensity
ptk2
rarb
relapses
tier
wisp1
Tagcloud (Difference)
?
applicability
csmd1
delineate
emphasized
fadd
fgf4
fhit
floor
gains
gata4
imbalances
individualized
losses
mandatory
mccc1
mlpa
mouth
mtus1
multiplex
p428
panel
probe
probemix
propensity
ptk2
rarb
relapses
tier
wisp1
Tagcloud (Intersection)
?