ACTR2 and ELF5

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ACTR2	ELF5
Gene Name		ARP2 actin-related protein 2 homolog (yeast)	E74-like factor 5 (ets domain transcription factor)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Arp2/3 Protein Complex Focal Adhesion Actin Cytoskeleton Membrane Actin Cap Cell Projection Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Structural Constituent Of Cytoskeleton ATP Binding Actin Filament Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
	Biological Process	Movement Of Cell Or Subcellular Component Establishment Or Maintenance Of Cell Polarity Axon Guidance Asymmetric Cell Division Meiotic Chromosome Movement Towards Spindle Pole Cytoplasmic Transport Meiotic Cytokinesis Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Cilium Assembly Innate Immune Response Ephrin Receptor Signaling Pathway Spindle Localization	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Ectoderm Development Cell Proliferation Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Mammary Gland Epithelial Cell Differentiation
Pathways		EPHB-mediated forward signaling Axon guidance EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS			β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374)
Protein-Protein Interactions		13 interactors: ACTC1 ACTR3 ARPC1B ARPC4 ARPC5 BMP2 CTTN ELF5 HCLS1 IQGAP2 WASF1 WASF2 WASL	8 interactors: ACTR2 FRZB NFE2 NRIP2 RPS15A SIRT6 SS18L1 UBQLN4
Entrez ID		10097	2001
HPRD ID		05023	05525
Ensembl ID		ENSG00000138071	ENSG00000135374
Uniprot IDs		P61160	A6XAE6 A8K443 Q9UKW6
PDB IDs			1WWX
Enriched GO Terms of Interacting Partners?		Actin Filament Organization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Actin Cytoskeleton Organization Actin Filament-based Process Regulation Of Actin Filament-based Process Regulation Of Cytoskeleton Organization Positive Regulation Of Organelle Organization Cytoskeleton Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Actin Filament Polymerization Regulation Of Organelle Organization Arp2/3 Complex-mediated Actin Nucleation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Actin Nucleation Regulation Of Cellular Component Organization Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Positive Regulation Of Protein Complex Assembly Actin Polymerization Or Depolymerization Actin Filament Polymerization Movement Of Cell Or Subcellular Component Organelle Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Phagocytosis Ephrin Receptor Signaling Pathway Protein Polymerization Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Morphogenesis Endocytosis Cell Differentiation Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Development Cell Projection Morphogenesis Cell Part Morphogenesis Immune Response-regulating Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process System Development Actin Filament-based Movement Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Anatomical Structure Morphogenesis Positive Regulation Of Immune Response
Tagcloud ?			alveolar cited1 collectively conditional cre disruption encodes except foxa1 knockout lineage luminal master mature mechanistically mecs mmtv mutated profound rb1 represses rescued runx runx1 secretory subpopulation subpopulations tf trp53
Tagcloud (Difference) ?			alveolar cited1 collectively conditional cre disruption encodes except foxa1 knockout lineage luminal master mature mechanistically mecs mmtv mutated profound rb1 represses rescued runx runx1 secretory subpopulation subpopulations tf trp53
Tagcloud (Intersection) ?