ACTR2 and ARPC1B

Number of citations of the paper that reports this interaction (PMID 11721045)
137

Data Source:
BioGRID (biochemical, biochemical)
HPRD (in vitro, in vivo)

		ACTR2	ARPC1B
Gene Name		ARP2 actin-related protein 2 homolog (yeast)	actin related protein 2/3 complex, subunit 1B, 41kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Arp2/3 Protein Complex Focal Adhesion Actin Cytoskeleton Membrane Actin Cap Cell Projection Extracellular Vesicular Exosome	Cytoplasm Arp2/3 Protein Complex Focal Adhesion Actin Cytoskeleton Extracellular Vesicular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton ATP Binding Actin Filament Binding	Structural Constituent Of Cytoskeleton Actin Filament Binding
	Biological Process	Movement Of Cell Or Subcellular Component Establishment Or Maintenance Of Cell Polarity Axon Guidance Asymmetric Cell Division Meiotic Chromosome Movement Towards Spindle Pole Cytoplasmic Transport Meiotic Cytokinesis Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Cilium Assembly Innate Immune Response Ephrin Receptor Signaling Pathway Spindle Localization	Movement Of Cell Or Subcellular Component Arp2/3 Complex-mediated Actin Nucleation
Pathways		EPHB-mediated forward signaling Axon guidance EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ACTC1 ACTR3 ARPC1B ARPC4 ARPC5 BMP2 CTTN ELF5 HCLS1 IQGAP2 WASF1 WASF2 WASL	10 interactors: ACTB ACTR2 APP ARPC2 ARPC4 ARPC5 AURKA PAK1 SRPK2 WAS
Entrez ID		10097	10095
HPRD ID		05023	10366
Ensembl ID		ENSG00000138071	ENSG00000130429
Uniprot IDs		P61160	A4D275 O15143
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Filament Organization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Actin Cytoskeleton Organization Actin Filament-based Process Regulation Of Actin Filament-based Process Regulation Of Cytoskeleton Organization Positive Regulation Of Organelle Organization Cytoskeleton Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Actin Filament Polymerization Regulation Of Organelle Organization Arp2/3 Complex-mediated Actin Nucleation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Actin Nucleation Regulation Of Cellular Component Organization Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Positive Regulation Of Protein Complex Assembly Actin Polymerization Or Depolymerization Actin Filament Polymerization Movement Of Cell Or Subcellular Component Organelle Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Phagocytosis Ephrin Receptor Signaling Pathway Protein Polymerization Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Morphogenesis Endocytosis Cell Differentiation Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Development Cell Projection Morphogenesis Cell Part Morphogenesis Immune Response-regulating Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process System Development Actin Filament-based Movement Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Anatomical Structure Morphogenesis Positive Regulation Of Immune Response	Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Innate Immune Response Ephrin Receptor Signaling Pathway Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Neuron Projection Morphogenesis Endocytosis Immune Response-regulating Cell Surface Receptor Signaling Pathway Axon Guidance Positive Regulation Of Organelle Organization Immune Response Defense Response Positive Regulation Of Cytoskeleton Organization Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Immune Response-regulating Signaling Pathway Regulation Of Cytoskeleton Organization Neuron Development Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Cell Morphogenesis Chemotaxis Arp2/3 Complex-mediated Actin Nucleation Neuron Differentiation Positive Regulation Of Immune Response Cell Projection Organization Regulation Of Actin Cytoskeleton Organization Cell Morphogenesis Involved In Differentiation Regulation Of Actin Filament-based Process Immune System Process Actin Nucleation Vesicle-mediated Transport Regulation Of Immune Response Movement Of Cell Or Subcellular Component Anatomical Structure Morphogenesis Positive Regulation Of Immune System Process Regulation Of Organelle Organization Generation Of Neurons Neurogenesis Cell Development Actin Cytoskeleton Organization Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Actin Filament-based Process Actin Filament Organization
Tagcloud ?			5q cd14 conjunction crtap cxcr4 damaged del exact exactly exert explain help ie impact lenalidomide microarray monocytes myelodysplastic necrosis niche profiling remission repressed restore stability stroma suppress tnf upregulated
Tagcloud (Difference) ?			5q cd14 conjunction crtap cxcr4 damaged del exact exactly exert explain help ie impact lenalidomide microarray monocytes myelodysplastic necrosis niche profiling remission repressed restore stability stroma suppress tnf upregulated
Tagcloud (Intersection) ?