CTTN and CTTNBP2

Number of citations of the paper that reports this interaction (PMID 9813110)
18

Data Source:
HPRD (in vitro)

		CTTN	CTTNBP2
Gene Name		cortactin	cortactin binding protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Cytoskeleton Actin Filament Coated Pit Focal Adhesion Cell Cortex Voltage-gated Potassium Channel Complex Lamellipodium Growth Cone Cortical Cytoskeleton Dendritic Spine Extracellular Vesicular Exosome Mitotic Spindle Midzone	Cell Cortex Synaptic Vesicle Dendritic Spine
	Molecular Function	Protein Binding	SH3 Domain Binding
	Biological Process	Intracellular Protein Transport Receptor-mediated Endocytosis Substrate-dependent Cell Migration, Cell Extension Actin Filament Polymerization Regulation Of Axon Extension Positive Regulation Of Actin Filament Polymerization Actin Cytoskeleton Reorganization Focal Adhesion Assembly Neuron Projection Morphogenesis Cell Motility Dendritic Spine Maintenance Lamellipodium Organization Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Brain Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		36 interactors: ACD ACTA1 ACTG1 ACTR2 ACTR3 ANKZF1 ARHGAP17 ARHGAP8 CASP3 CD2AP CHD3 CTNND1 CTNND2 CTTNBP2 DNM1 DNM2 FER FGD1 GRB2 HAX1 HDAC6 HIP1R KCNA2 MET MYLK SDC3 SHANK2 SIRT1 SPRR2A SRC SYK TINF2 TJP1 TNK2 WASL WIPF1	1 interactors: CTTN
Entrez ID		2017	83992
HPRD ID		01268	09890
Ensembl ID		ENSG00000085733	ENSG00000077063
Uniprot IDs		Q14247 Q53HG7	Q20BG9 Q8WZ74
PDB IDs		1X69 2D1X
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Anatomical Structure Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Endocytosis Fc Receptor Signaling Pathway Cellular Response To Stimulus Cellular Component Assembly Regulation Of Cellular Component Organization Actin Cytoskeleton Organization Actin Filament-based Process Anatomical Structure Development Response To External Stimulus Developmental Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Organelle Organization Phagocytosis Cell Communication Positive Regulation Of Organelle Organization Multicellular Organismal Development Immune Response-activating Cell Surface Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Organelle Organization Movement Of Cell Or Subcellular Component Chemotaxis Immune Response-regulating Signaling Pathway System Development Signaling Cytoskeleton Organization Signal Transduction Positive Regulation Of Immune System Process Response To Stimulus Cell Projection Organization Cell Morphogenesis Involved In Differentiation Axon Guidance Locomotion Innate Immune Response Positive Regulation Of Protein Complex Assembly Regulation Of Immune System Process Cell Morphogenesis Actin Filament Organization Positive Regulation Of Immune Response Neuron Projection Morphogenesis Positive Regulation Of Cellular Component Biogenesis Regulation Of Immune Response Peptidyl-tyrosine Autophosphorylation Regulation Of Protein Complex Assembly Positive Regulation Of Cytoskeleton Organization	Dendritic Spine Maintenance Substrate-dependent Cell Migration, Cell Extension Dendritic Spine Organization Cellular Component Maintenance Focal Adhesion Assembly Substrate-dependent Cell Migration Actin Filament Polymerization Adherens Junction Assembly Cell-substrate Junction Assembly Lamellipodium Organization Actin Cytoskeleton Reorganization Regulation Of Axon Extension Actin Polymerization Or Depolymerization Adherens Junction Organization Protein Polymerization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cell Size Regulation Of Axonogenesis Cell-matrix Adhesion Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Junction Assembly Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Cell-cell Junction Organization Cell-substrate Adhesion Negative Regulation Of Apoptotic Signaling Pathway Cell Projection Assembly Regulation Of Developmental Growth Actin Filament Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Cellular Protein Complex Assembly Regulation Of Cell Growth Receptor-mediated Endocytosis Regulation Of Actin Cytoskeleton Organization Regulation Of Neuron Projection Development Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process
Tagcloud ?		applicability csmd1 delineate emphasized fadd fgf4 fhit floor gains gata4 imbalances individualized losses mandatory mccc1 mlpa mouth mtus1 multiplex p428 panel probe probemix propensity ptk2 rarb relapses tier wisp1	3c anticipate asz1 away bait cftr conductance constructs cooperatively correspond cystic depend designing dnase enable encompasses flanking governing hypersensitive intergenic intronic introns kb locus looped lying modify recruit transgenes
Tagcloud (Difference) ?		applicability csmd1 delineate emphasized fadd fgf4 fhit floor gains gata4 imbalances individualized losses mandatory mccc1 mlpa mouth mtus1 multiplex p428 panel probe probemix propensity ptk2 rarb relapses tier wisp1	3c anticipate asz1 away bait cftr conductance constructs cooperatively correspond cystic depend designing dnase enable encompasses flanking governing hypersensitive intergenic intronic introns kb locus looped lying modify recruit transgenes
Tagcloud (Intersection) ?