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CTTN and ARHGAP17
Number of citations of the paper that reports this interaction (PMID
11431473
)
23
Data Source:
HPRD
(in vitro)
CTTN
ARHGAP17
Gene Name
cortactin
Rho GTPase activating protein 17
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ruffle
Cytoplasm
Cytoskeleton
Actin Filament
Coated Pit
Focal Adhesion
Cell Cortex
Voltage-gated Potassium Channel Complex
Lamellipodium
Growth Cone
Cortical Cytoskeleton
Dendritic Spine
Extracellular Vesicular Exosome
Mitotic Spindle Midzone
Cytosol
Plasma Membrane
Tight Junction
Molecular Function
Protein Binding
GTPase Activator Activity
Protein Binding
SH3 Domain Binding
Biological Process
Intracellular Protein Transport
Receptor-mediated Endocytosis
Substrate-dependent Cell Migration, Cell Extension
Actin Filament Polymerization
Regulation Of Axon Extension
Positive Regulation Of Actin Filament Polymerization
Actin Cytoskeleton Reorganization
Focal Adhesion Assembly
Neuron Projection Morphogenesis
Cell Motility
Dendritic Spine Maintenance
Lamellipodium Organization
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Small GTPase Mediated Signal Transduction
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Pathways
Rho GTPase cycle
Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions
36 interactors:
ACD
ACTA1
ACTG1
ACTR2
ACTR3
ANKZF1
ARHGAP17
ARHGAP8
CASP3
CD2AP
CHD3
CTNND1
CTNND2
CTTNBP2
DNM1
DNM2
FER
FGD1
GRB2
HAX1
HDAC6
HIP1R
KCNA2
MET
MYLK
SDC3
SHANK2
SIRT1
SPRR2A
SRC
SYK
TINF2
TJP1
TNK2
WASL
WIPF1
16 interactors:
ABL1
APP
BTK
CDC42
CRK
CTTN
DNMBP
FNBP1
GRB2
LCK
PACSIN1
PIK3R1
RAC1
SH3GLB1
SRC
TRIP10
Entrez ID
2017
55114
HPRD ID
01268
12207
Ensembl ID
ENSG00000085733
ENSG00000140750
Uniprot IDs
Q14247
Q53HG7
Q68EM7
PDB IDs
1X69
2D1X
Enriched GO Terms of Interacting Partners
?
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Anatomical Structure Morphogenesis
Enzyme Linked Receptor Protein Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Endocytosis
Fc Receptor Signaling Pathway
Cellular Response To Stimulus
Cellular Component Assembly
Regulation Of Cellular Component Organization
Actin Cytoskeleton Organization
Actin Filament-based Process
Anatomical Structure Development
Response To External Stimulus
Developmental Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Organelle Organization
Phagocytosis
Cell Communication
Positive Regulation Of Organelle Organization
Multicellular Organismal Development
Immune Response-activating Cell Surface Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Organelle Organization
Movement Of Cell Or Subcellular Component
Chemotaxis
Immune Response-regulating Signaling Pathway
System Development
Signaling
Cytoskeleton Organization
Signal Transduction
Positive Regulation Of Immune System Process
Response To Stimulus
Cell Projection Organization
Cell Morphogenesis Involved In Differentiation
Axon Guidance
Locomotion
Innate Immune Response
Positive Regulation Of Protein Complex Assembly
Regulation Of Immune System Process
Cell Morphogenesis
Actin Filament Organization
Positive Regulation Of Immune Response
Neuron Projection Morphogenesis
Positive Regulation Of Cellular Component Biogenesis
Regulation Of Immune Response
Peptidyl-tyrosine Autophosphorylation
Regulation Of Protein Complex Assembly
Positive Regulation Of Cytoskeleton Organization
Endocytosis
Fc Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Vesicle-mediated Transport
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Blood Coagulation
Hemostasis
Immune Response-regulating Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
T Cell Costimulation
Innate Immune Response
Platelet Activation
Regulation Of Body Fluid Levels
Wound Healing
Positive Regulation Of Immune Response
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Activation
Response To Wounding
Phagocytosis
Positive Regulation Of Cell Activation
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of Immune Response
Immune Response
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Immune System Process
Defense Response
Regulation Of Cell-cell Adhesion
Neuron Projection Morphogenesis
Regulation Of Lymphocyte Activation
Positive Regulation Of T Cell Activation
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Homotypic Cell-cell Adhesion
Neurotrophin Signaling Pathway
Leukocyte Migration
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Signal Transduction
Positive Regulation Of Cell-cell Adhesion
Peptidyl-tyrosine Autophosphorylation
Regulation Of Cell Activation
Neuron Projection Development
Cell Migration
Regulation Of Phosphatidylinositol 3-kinase Activity
Regulation Of T Cell Activation
Cell Projection Morphogenesis
Locomotion
Transport
Regulation Of Signaling
Tagcloud
?
applicability
csmd1
delineate
emphasized
fadd
fgf4
fhit
floor
gains
gata4
imbalances
individualized
losses
mandatory
mccc1
mlpa
mouth
mtus1
multiplex
p428
panel
probe
probemix
propensity
ptk2
rarb
relapses
tier
wisp1
Tagcloud (Difference)
?
applicability
csmd1
delineate
emphasized
fadd
fgf4
fhit
floor
gains
gata4
imbalances
individualized
losses
mandatory
mccc1
mlpa
mouth
mtus1
multiplex
p428
panel
probe
probemix
propensity
ptk2
rarb
relapses
tier
wisp1
Tagcloud (Intersection)
?