DNM1L and VIM

Number of citations of the paper that reports this interaction (PMID 15383276)
99

Data Source:
HPRD (two hybrid, in vitro)

		DNM1L	VIM
Gene Name		dynamin 1-like	vimentin
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Peroxisome Golgi Apparatus Cytosol Microtubule Coated Pit Membrane Cell Junction Synaptic Vesicle Membrane Intracellular Membrane-bounded Organelle Protein Complex Perinuclear Region Of Cytoplasm	Cytoplasm Peroxisome Cytosol Cytoskeleton Intermediate Filament Plasma Membrane Focal Adhesion Cell Leading Edge Neuron Projection Intermediate Filament Cytoskeleton Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Lipid Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity	Glycoprotein Binding Double-stranded RNA Binding Structural Constituent Of Cytoskeleton Structural Constituent Of Eye Lens Protein Binding Protein C-terminus Binding Identical Protein Binding Scaffold Protein Binding
	Biological Process	Mitochondrial Fission Release Of Cytochrome C From Mitochondria Dynamin Polymerization Involved In Mitochondrial Fission Endocytosis Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Mitochondrion Organization Peroxisome Fission Regulation Of Protein Oligomerization Positive Regulation Of Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Protein Secretion Protein Homotetramerization Membrane Fusion Necroptotic Process Mitochondrion Morphogenesis Protein Localization To Mitochondrion Positive Regulation Of Mitochondrial Fission Mitochondrial Membrane Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Peroxisome Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Movement Of Cell Or Subcellular Component Positive Regulation Of Gene Expression Negative Regulation Of Neuron Projection Development Astrocyte Development Viral Process Muscle Filament Sliding Intermediate Filament Organization Bergmann Glial Cell Differentiation SMAD Protein Signal Transduction Lens Fiber Cell Development
Pathways		Programmed Cell Death Apoptotic execution phase	Apoptotic cleavage of cellular proteins Striated Muscle Contraction Programmed Cell Death Apoptotic execution phase Caspase-mediated cleavage of cytoskeletal proteins
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: FIS1 GSK3B MAGEA1 MAGEA3 MAP3K10 MFF MIEF2 MUL1 PARK2 RRM2 SCG3 SH3GL1 SIRT3 VIM ZBTB24	140 interactors: ABLIM1 AKT1 ALS2CR11 ANKRD35 ANXA7 APIP APLP1 APP ARMCX2 ATN1 BFSP1 BHLHE40 BRD1 CAMK2D CAPN1 CASP3 CASP6 CASP7 CASP8 CASP9 CDH5 CDK1 CDKN1A CHD3 COPS6 CRCT1 CREB1 CRMP1 CWF19L2 DCTN1 DEFB1 DGCR14 DIS3L2 DNM1L DPPA4 DSP DYNLL1 EIF3I FABP4 FAM107A FAM118B FUBP1 GADD45A GFAP GOPC GRB2 GSK3B HABP4 HAP1 HMG20B HTRA2 ING5 ITGB4 IVNS1ABP KARS KAT7 KIAA0408 KIAA1377 KIF15 KRT20 LOR LRIF1 MAFG MAN2A2 MEN1 MICAL1 MRPL44 NEFL NFATC2 NIF3L1 NME2 NOC4L NR1H2 NUP85 OSBP2 PAK2 PDLIM1 PIAS4 PKD1 PKN1 PKP1 PLA2G2A PLA2G4A PLEC PNMA5 POLR1C PPHLN1 PPL PRKACA PRPH PSMA1 PSMD7 PSME1 PUF60 RAB8B RABAC1 RAD51 RBM48 RIBC2 ROCK1 RPA1 SDCCAG3 SERBP1 SETDB1 SH3GL1 SH3GL3 SH3YL1 SIRT6 SLC25A6 SLC27A6 SMAD3 SRRT STX1A SUMO2 SUMO3 SYN1 TAB2 TCHP TNFRSF14 TNNT1 TRIM28 TRIM29 TRIOBP TSC22D1 TTR TUBGCP4 TXLNB TXN TXN2 UPP1 UPP2 UROD UTP14A WBP11 XRCC4 YAE1D1 YWHAE YWHAZ ZHX1 ZNF384
Entrez ID		10059	7431
HPRD ID		04833	01899
Ensembl ID		ENSG00000087470	ENSG00000026025
Uniprot IDs		B4DGC9 B4DYR6 G8JLD5 J3KPI2 O00429 Q59GN9	P08670
PDB IDs		4BEJ 4H1U 4H1V	1GK4 1GK6 1GK7 3G1E 3KLT 3S4R 3SSU 3SWK 3TRT 3UF1
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Mitochondrial Fission Mitochondrion Organization Positive Regulation Of Organelle Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Mitochondrial Fusion Regulation Of Intracellular Transport Regulation Of Mitochondrial Fusion Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Organelle Organization Positive Regulation Of Intracellular Transport Apoptotic Process Protein Localization To Mitochondrion Mitochondrial Fragmentation Involved In Apoptotic Process Programmed Cell Death Regulation Of Intracellular Protein Transport Regulation Of Cellular Localization Cell Death Death Regulation Of Protein Transport Peroxisome Fission Positive Regulation Of Proteolysis Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Transport Positive Regulation Of Signal Transduction Mitochondrial Fusion Regulation Of Cellular Component Organization Regulation Of Protein Localization Regulation Of Apoptotic Process Mitochondrion Morphogenesis Regulation Of JNK Cascade Mitochondrion Degradation Regulation Of Cell Death Release Of Cytochrome C From Mitochondria Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Mitochondrion Organization Protein Localization To Organelle Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Organelle Disassembly Activation Of JUN Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Peroxisome Organization	Programmed Cell Death Apoptotic Process Cell Death Death Execution Phase Of Apoptosis Regulation Of Cell Death Response To Abiotic Stimulus Regulation Of Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Response To Stress Positive Regulation Of Proteolysis Regulation Of Cellular Localization Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Regulation Of Cellular Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Cell Death Nitrogen Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Localization Organelle Organization Cell Cycle Process Cellular Response To Stress Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Death Regulation Of Protein Metabolic Process Positive Regulation Of Apoptotic Signaling Pathway Gene Expression Immune System Process Regulation Of Intracellular Transport Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Cycle Anatomical Structure Development Positive Regulation Of Signal Transduction Mitotic Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Programmed Cell Death Cellular Process Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Viral Process Intrinsic Apoptotic Signaling Pathway
Tagcloud ?		affirmed brains compendia computationally distinctly emerges etiological etiology forests hippocampus inferred ins1 ins2 modules mutual networks neurotrophic notable orphan orthologs postmortem probable rora scheme tia1 tied ties trees unresolved	10p13 17q21 5q15 6p24 australian british cl cleft crtl1 d1s58 d1s65 der excluded f13a1 flank inheritance linkage lip lod multipoint palate rara syndromic theta unrelated van vws woude z
Tagcloud (Difference) ?		affirmed brains compendia computationally distinctly emerges etiological etiology forests hippocampus inferred ins1 ins2 modules mutual networks neurotrophic notable orphan orthologs postmortem probable rora scheme tia1 tied ties trees unresolved	10p13 17q21 5q15 6p24 australian british cl cleft crtl1 d1s58 d1s65 der excluded f13a1 flank inheritance linkage lip lod multipoint palate rara syndromic theta unrelated van vws woude z
Tagcloud (Intersection) ?