DNM1L and MAGEA3

Number of citations of the paper that reports this interaction (PMID 18330356)
4

Data Source:
BioGRID (two hybrid)

		DNM1L	MAGEA3
Gene Name		dynamin 1-like	melanoma antigen family A, 3
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Peroxisome Golgi Apparatus Cytosol Microtubule Coated Pit Membrane Cell Junction Synaptic Vesicle Membrane Intracellular Membrane-bounded Organelle Protein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding Lipid Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Mitochondrial Fission Release Of Cytochrome C From Mitochondria Dynamin Polymerization Involved In Mitochondrial Fission Endocytosis Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Mitochondrion Organization Peroxisome Fission Regulation Of Protein Oligomerization Positive Regulation Of Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Protein Secretion Protein Homotetramerization Membrane Fusion Necroptotic Process Mitochondrion Morphogenesis Protein Localization To Mitochondrion Positive Regulation Of Mitochondrial Fission Mitochondrial Membrane Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Peroxisome Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: FIS1 GSK3B MAGEA1 MAGEA3 MAP3K10 MFF MIEF2 MUL1 PARK2 RRM2 SCG3 SH3GL1 SIRT3 VIM ZBTB24	4 interactors: DNM1L HLA-DRB1 HTT TRIM28
Entrez ID		10059	4102
HPRD ID		04833	02166
Ensembl ID		ENSG00000087470	ENSG00000221867
Uniprot IDs		B4DGC9 B4DYR6 G8JLD5 J3KPI2 O00429 Q59GN9	P43357
PDB IDs		4BEJ 4H1U 4H1V	1QEW
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Mitochondrial Fission Mitochondrion Organization Positive Regulation Of Organelle Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Mitochondrial Fusion Regulation Of Intracellular Transport Regulation Of Mitochondrial Fusion Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Organelle Organization Positive Regulation Of Intracellular Transport Apoptotic Process Protein Localization To Mitochondrion Mitochondrial Fragmentation Involved In Apoptotic Process Programmed Cell Death Regulation Of Intracellular Protein Transport Regulation Of Cellular Localization Cell Death Death Regulation Of Protein Transport Peroxisome Fission Positive Regulation Of Proteolysis Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Transport Positive Regulation Of Signal Transduction Mitochondrial Fusion Regulation Of Cellular Component Organization Regulation Of Protein Localization Regulation Of Apoptotic Process Mitochondrion Morphogenesis Regulation Of JNK Cascade Mitochondrion Degradation Regulation Of Cell Death Release Of Cytochrome C From Mitochondria Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Mitochondrion Organization Protein Localization To Organelle Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Organelle Disassembly Activation Of JUN Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Peroxisome Organization	Protein Oligomerization Positive Regulation Of Transport Protein Complex Assembly Positive Regulation Of Protein Transport Cellular Component Assembly Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Protein Tetramerization Regulation Of Protein Localization Neural Plate Formation Mitochondrial Membrane Fission Dynamin Polymerization Involved In Mitochondrial Fission Negative Regulation Of DNA Demethylation Polysaccharide Assembly With MHC Class II Protein Complex Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Regulation Of Cellular Localization Positive Regulation Of Protein Secretion Mesenchyme Development Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Regulation Of Peroxisome Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Protein Phosphatase Type 2A Activity Quinolinate Biosynthetic Process Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Assembly Negative Regulation Of Synaptic Transmission, Dopaminergic Protein Homooligomerization Convergent Extension Involved In Axis Elongation Lactate Biosynthetic Process Regulation Of Genetic Imprinting DNA Methylation Involved In Embryo Development Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Paraxial Mesoderm Formation Quinolinate Metabolic Process Cellular Response To CGMP Positive Regulation Of Secretion Cellular Protein Complex Assembly Response To CGMP Serotonin Transport Sperm Ejaculation Neural Plate Morphogenesis L-glutamate Import Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Mitochondrial Fission Regulation Of Protein Secretion Mitochondrion Organization Citrulline Metabolic Process Lactate Metabolic Process Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Tagcloud ?		affirmed brains compendia computationally distinctly emerges etiological etiology forests hippocampus inferred ins1 ins2 modules mutual networks neurotrophic notable orphan orthologs postmortem probable rora scheme tia1 tied ties trees unresolved	acrbp antigens attractive chemoradiation ctag1b ctag2 embedded encountered excision formalin frozen germ homogenous immunogenic immunotherapy lage liposarcoma liposarcomas mainstay myxoid paraffin prame real round ssx2 testicular testis
Tagcloud (Difference) ?		affirmed brains compendia computationally distinctly emerges etiological etiology forests hippocampus inferred ins1 ins2 modules mutual networks neurotrophic notable orphan orthologs postmortem probable rora scheme tia1 tied ties trees unresolved	acrbp antigens attractive chemoradiation ctag1b ctag2 embedded encountered excision formalin frozen germ homogenous immunogenic immunotherapy lage liposarcoma liposarcomas mainstay myxoid paraffin prame real round ssx2 testicular testis
Tagcloud (Intersection) ?