DNM1L and MIEF2

Number of citations of the paper that reports this interaction (PMID 23530241)
10

Data Source:
BioGRID (pull down)

		DNM1L	MIEF2
Gene Name		dynamin 1-like	mitochondrial elongation factor 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Peroxisome Golgi Apparatus Cytosol Microtubule Coated Pit Membrane Cell Junction Synaptic Vesicle Membrane Intracellular Membrane-bounded Organelle Protein Complex Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Outer Membrane Peroxisome Integral Component Of Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Lipid Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Mitochondrial Fission Release Of Cytochrome C From Mitochondria Dynamin Polymerization Involved In Mitochondrial Fission Endocytosis Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Mitochondrion Organization Peroxisome Fission Regulation Of Protein Oligomerization Positive Regulation Of Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Protein Secretion Protein Homotetramerization Membrane Fusion Necroptotic Process Mitochondrion Morphogenesis Protein Localization To Mitochondrion Positive Regulation Of Mitochondrial Fission Mitochondrial Membrane Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Peroxisome Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Mitochondrion Organization Mitochondrial Fusion Positive Regulation Of Protein Homooligomerization Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane
Pathways		Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: FIS1 GSK3B MAGEA1 MAGEA3 MAP3K10 MFF MIEF2 MUL1 PARK2 RRM2 SCG3 SH3GL1 SIRT3 VIM ZBTB24	6 interactors: AGTRAP DNM1L PSMF1 RABAC1 UBQLN1 UBQLN4
Entrez ID		10059	125170
HPRD ID		04833	18074
Ensembl ID		ENSG00000087470	ENSG00000177427
Uniprot IDs		B4DGC9 B4DYR6 G8JLD5 J3KPI2 O00429 Q59GN9	Q96C03
PDB IDs		4BEJ 4H1U 4H1V
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Mitochondrial Fission Mitochondrion Organization Positive Regulation Of Organelle Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Mitochondrial Fusion Regulation Of Intracellular Transport Regulation Of Mitochondrial Fusion Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Organelle Organization Positive Regulation Of Intracellular Transport Apoptotic Process Protein Localization To Mitochondrion Mitochondrial Fragmentation Involved In Apoptotic Process Programmed Cell Death Regulation Of Intracellular Protein Transport Regulation Of Cellular Localization Cell Death Death Regulation Of Protein Transport Peroxisome Fission Positive Regulation Of Proteolysis Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Transport Positive Regulation Of Signal Transduction Mitochondrial Fusion Regulation Of Cellular Component Organization Regulation Of Protein Localization Regulation Of Apoptotic Process Mitochondrion Morphogenesis Regulation Of JNK Cascade Mitochondrion Degradation Regulation Of Cell Death Release Of Cytochrome C From Mitochondria Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Mitochondrion Organization Protein Localization To Organelle Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Organelle Disassembly Activation Of JUN Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Peroxisome Organization	Mitochondrial Membrane Fission Dynamin Polymerization Involved In Mitochondrial Fission Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Peroxisome Organization Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Ubiquitination Response To Hypoxia Angiotensin-activated Signaling Pathway Positive Regulation Of Mitochondrial Fission Mitochondrial Fragmentation Involved In Apoptotic Process Regulation Of Apoptotic Process Peroxisome Fission Regulation Of Cell Death Regulation Of Protein Catabolic Process Regulation Of Mitochondrial Fission Regulation Of Cellular Protein Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Release Of Cytochrome C From Mitochondria Mitochondrion Morphogenesis Mitochondrial Fission Regulation Of Protein Oligomerization
Tagcloud ?		affirmed brains compendia computationally distinctly emerges etiological etiology forests hippocampus inferred ins1 ins2 modules mutual networks neurotrophic notable orphan orthologs postmortem probable rora scheme tia1 tied ties trees unresolved
Tagcloud (Difference) ?		affirmed brains compendia computationally distinctly emerges etiological etiology forests hippocampus inferred ins1 ins2 modules mutual networks neurotrophic notable orphan orthologs postmortem probable rora scheme tia1 tied ties trees unresolved
Tagcloud (Intersection) ?