DNM1L and SH3GL1

Number of citations of the paper that reports this interaction (PMID 18330356)
4

Data Source:
BioGRID (two hybrid)

		DNM1L	SH3GL1
Gene Name		dynamin 1-like	SH3-domain GRB2-like 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Peroxisome Golgi Apparatus Cytosol Microtubule Coated Pit Membrane Cell Junction Synaptic Vesicle Membrane Intracellular Membrane-bounded Organelle Protein Complex Perinuclear Region Of Cytoplasm	Podosome Cytoplasm Cell Junction Early Endosome Membrane Cell Projection
	Molecular Function	GTPase Activity Protein Binding GTP Binding Lipid Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Lipid Binding Phosphatase Binding Identical Protein Binding GTPase Binding
	Biological Process	Mitochondrial Fission Release Of Cytochrome C From Mitochondria Dynamin Polymerization Involved In Mitochondrial Fission Endocytosis Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Mitochondrion Organization Peroxisome Fission Regulation Of Protein Oligomerization Positive Regulation Of Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Protein Secretion Protein Homotetramerization Membrane Fusion Necroptotic Process Mitochondrion Morphogenesis Protein Localization To Mitochondrion Positive Regulation Of Mitochondrial Fission Mitochondrial Membrane Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Peroxisome Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Endocytosis Signal Transduction Central Nervous System Development
Pathways		Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: FIS1 GSK3B MAGEA1 MAGEA3 MAP3K10 MFF MIEF2 MUL1 PARK2 RRM2 SCG3 SH3GL1 SIRT3 VIM ZBTB24	26 interactors: ARHGAP8 AXIN1 B3GAT1 CREBBP DNM1 DNM1L DPPA4 DPYSL4 FAM102A GPKOW ITSN2 LRRK2 MAL2 MTA1 PDCD6IP PML PTPRO SEPT8 SH2D4A SH3D19 SH3GL2 SH3GL3 SYNJ1 VIM VPS37C YWHAZ
Entrez ID		10059	6455
HPRD ID		04833	03462
Ensembl ID		ENSG00000087470	ENSG00000141985
Uniprot IDs		B4DGC9 B4DYR6 G8JLD5 J3KPI2 O00429 Q59GN9	Q6FGM0 Q99961
PDB IDs		4BEJ 4H1U 4H1V
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Mitochondrial Fission Mitochondrion Organization Positive Regulation Of Organelle Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Mitochondrial Fusion Regulation Of Intracellular Transport Regulation Of Mitochondrial Fusion Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Organelle Organization Positive Regulation Of Intracellular Transport Apoptotic Process Protein Localization To Mitochondrion Mitochondrial Fragmentation Involved In Apoptotic Process Programmed Cell Death Regulation Of Intracellular Protein Transport Regulation Of Cellular Localization Cell Death Death Regulation Of Protein Transport Peroxisome Fission Positive Regulation Of Proteolysis Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Transport Positive Regulation Of Signal Transduction Mitochondrial Fusion Regulation Of Cellular Component Organization Regulation Of Protein Localization Regulation Of Apoptotic Process Mitochondrion Morphogenesis Regulation Of JNK Cascade Mitochondrion Degradation Regulation Of Cell Death Release Of Cytochrome C From Mitochondria Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Mitochondrion Organization Protein Localization To Organelle Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Organelle Disassembly Activation Of JUN Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Peroxisome Organization	Vesicle-mediated Transport Positive Regulation Of Protein Autoubiquitination Endocytosis Regulation Of Protein Autoubiquitination Regulation Of Cellular Component Organization Protein Localization To Mitochondrion Regulation Of Cellular Localization Regulation Of Protein Ubiquitination Cellular Localization Cell Death Death Regulation Of Mitochondrial Fission Regulation Of Signaling Organelle Organization Regulation Of Mitochondrion Organization Membrane Organization Cell Part Morphogenesis Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Viral Process Positive Regulation Of Proteolysis Entrainment Of Circadian Clock By Photoperiod Signaling Cell Development Virion Assembly Transport Apoptotic Process Cell Communication Photoperiodism Entrainment Of Circadian Clock Positive Regulation Of Protein Ubiquitination Anatomical Structure Morphogenesis Neuron Projection Morphogenesis Programmed Cell Death Regulation Of Vesicle-mediated Transport Signal Transduction Regulation Of Protein Catabolic Process Axon Guidance Synaptic Vesicle Endocytosis Generation Of Neurons Synaptic Vesicle Recycling Positive Regulation Of Organelle Organization Neuron Differentiation Organelle Localization Regulation Of Synaptic Vesicle Transport Regulation Of Intracellular Transport Neurogenesis Positive Regulation Of Apoptotic Signaling Pathway Neuron Projection Development Positive Regulation Of Synaptic Vesicle Uncoating
Tagcloud ?		affirmed brains compendia computationally distinctly emerges etiological etiology forests hippocampus inferred ins1 ins2 modules mutual networks neurotrophic notable orphan orthologs postmortem probable rora scheme tia1 tied ties trees unresolved	antigens array autoantibodies autoantibody autologous c6 clarification cloning curable deletion elicit elisa epitope establishment glioma gliomas grade grb2 homology immunological mutants oncogenic overlap serex serological spite subtle usually volunteers
Tagcloud (Difference) ?		affirmed brains compendia computationally distinctly emerges etiological etiology forests hippocampus inferred ins1 ins2 modules mutual networks neurotrophic notable orphan orthologs postmortem probable rora scheme tia1 tied ties trees unresolved	antigens array autoantibodies autoantibody autologous c6 clarification cloning curable deletion elicit elisa epitope establishment glioma gliomas grade grb2 homology immunological mutants oncogenic overlap serex serological spite subtle usually volunteers
Tagcloud (Intersection) ?