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PDCD6 and SH3KBP1
Number of citations of the paper that reports this interaction (PubMedID
10858458
)
0
Data Source:
BioGRID
(pull down)
HPRD
(in vitro)
PDCD6
SH3KBP1
Description
programmed cell death 6
SH3 domain containing kinase binding protein 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
ER To Golgi Transport Vesicle Membrane
Membrane
COPII Vesicle Coat
Cytoplasmic Vesicle
Cul3-RING Ubiquitin Ligase Complex
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Endoplasmic Reticulum Exit Site
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Postsynaptic Density
Membrane
Endocytic Vesicle
Cytoplasmic Vesicle Membrane
Cytoplasmic Vesicle
Neuron Projection
Synapse
Anchoring Junction
Glutamatergic Synapse
GABA-ergic Synapse
Molecular Function
Magnesium Ion Binding
Calcium Ion Binding
Protein Binding
Protein-macromolecule Adaptor Activity
Identical Protein Binding
Protein Homodimerization Activity
Protein-membrane Adaptor Activity
Metal Ion Binding
Protein Heterodimerization Activity
Protein Dimerization Activity
Calcium-dependent Protein Binding
Ubiquitin-like Ligase-substrate Adaptor Activity
Protein Binding
SH3 Domain Binding
Ubiquitin Protein Ligase Binding
Biological Process
Angiogenesis
Positive Regulation Of Endothelial Cell Proliferation
Intracellular Protein Transport
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Apoptotic Process
Positive Regulation Of Endothelial Cell Migration
Neural Crest Formation
Neural Crest Cell Development
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Negative Regulation Of TOR Signaling
Cellular Response To Heat
Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway
Positive Regulation Of Apoptotic Process
Positive Regulation Of Angiogenesis
COPII Vesicle Coating
Response To Calcium Ion
Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Apoptotic Signaling Pathway
Positive Regulation Of Protein Monoubiquitination
Endocytosis
Apoptotic Process
Cytoskeleton Organization
Actin Filament Organization
Cell-cell Signaling
Regulation Of Cell Shape
Cell Migration
Positive Regulation Of B Cell Activation
Pathways
EGFR downregulation
Negative regulation of MET activity
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Reelin signalling pathway
InlB-mediated entry of Listeria monocytogenes into host cell
Potential therapeutics for SARS
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Calcium
Zinc
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Zinc acetate
Diseases
GWAS
Hip circumference adjusted for BMI (
34021172
)
Waist circumference adjusted for body mass index (
34021172
)
Platelet count (
32888494
)
Interacting Genes
29 interacting genes:
ANXA11
ANXA7
BAG4
CDKN2A
CEBPA
CPNE1
CPNE2
CPNE4
DIAPH3
FAS
FASLG
FNDC3A
HEBP2
IGFALS
KLHL12
MAP3K5
MAPK1IP1L
MIA2
PDCD6IP
PEF1
PRR19
SARAF
SEC31A
SH3KBP1
SHISA4
TIMM22
UBC
VPS37C
YWHAQ
59 interacting genes:
ABI2
ANKS1A
ARAP3
ARHGAP27
ASAP1
ASAP2
BCAR1
BLNK
BMPR1B
CAPZA1
CBL
CBLB
CCDC57
CCDC88B
CD2
CYSRT1
DENND2A
EGLN1
GGN
GPRASP3
GRB2
HCK
HIVEP1
INPP5D
ITSN2
KPRP
KRTAP6-3
LZTS2
MVB12A
NEDD4
NELFA
PAK2
PDCD6
PDCD6IP
PIK3CA
PIK3R1
PNMA5
POLR2K
PSMA3
SEPTIN2
SEPTIN6
SH3BP2
SH3GL2
SH3GL3
SH3GLB1
SH3GLB2
SHKBP1
SOS1
SPRY2
STAP1
SYNJ1
TAF6
TJP2
TP53BP2
UBB
UBC
UBE2I
ZBTB7B
ZNF219
Entrez ID
10016
30011
HPRD ID
03035
02301
Ensembl ID
ENSG00000249915
ENSG00000147010
Uniprot IDs
A0A024QZ42
A0A087WZ38
O75340
Q53FC3
A0A8V8TNL0
A0A8V8TNT5
A0A8V8TNW8
A0A8V8TP27
A0A8V8TP33
A0A8V8TP40
A0A8V8TP63
A0A8V8TP69
A0A8V8TPM1
A0A8V8TQF6
A0A8V8TQU1
B7Z6E8
Q5JPT2
Q5JPT6
Q96B97
PDB IDs
2ZN8
2ZN9
2ZND
2ZNE
2ZRS
2ZRT
3AAJ
3AAK
3WXA
5GQQ
2BZ8
2K6D
2K9G
2N64
2O2O
2YDL
5ABS
Enriched GO Terms of Interacting Partners
?
Response To Metal Ion
Calcium-dependent Protein Binding
Response To Calcium Ion
Calcium-dependent Phospholipid Binding
Extracellular Exosome
COPII Vesicle Coat
Endoplasmic Reticulum Exit Site
Vesicle Membrane
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Neural Crest Formation
Necroptotic Signaling Pathway
Vesicle-mediated Transport
Phosphatidylserine Binding
ESCRT I Complex
Vesicle Organization
Cellular Response To Metal Ion
Replicative Senescence
Cellular Response To Calcium Ion
Programmed Necrotic Cell Death
Cellular Response To Tumor Necrosis Factor
Viral Budding Via Host ESCRT Complex
Membrane Organization
COPII Vesicle Coating
Cellular Localization
Viral Budding
Autophagy
Lymphocyte Apoptotic Process
T Cell Apoptotic Process
NF-kappaB Binding
Ligase Inhibitor Activity
Response To Tumor Necrosis Factor
RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding
Vesicle Cargo Loading
Golgi Vesicle Transport
TERT-RMRP Complex
Template-free RNA Nucleotidyltransferase
Positive Regulation Of Transdifferentiation
RNA-directed RNA Polymerase Complex
SiRNA Transcription
Negative Regulation Of MRNA Modification
Multivesicular Body Organization
Multivesicular Body Assembly
Stem Cell Development
Neural Crest Cell Development
Vesicle Coating
Stereocilia Tip-link Density
COPII-coated ER To Golgi Transport Vesicle
Cytokinetic Process
Apoptotic Signaling Pathway
SH3 Domain Binding
Cytosol
Phosphotyrosine Residue Binding
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme-linked Receptor Protein Signaling Pathway
Regulation Of ERBB Signaling Pathway
Cytoplasm
Immune Response-activating Cell Surface Receptor Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Antigen Receptor-mediated Signaling Pathway
Regulation Of Cellular Component Organization
Cell Surface Receptor Signaling Pathway
Regulation Of Actin Cytoskeleton Organization
Endocytosis
Regulation Of Actin Filament Organization
Immune Response-activating Signaling Pathway
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of ERBB Signaling Pathway
Insulin-like Growth Factor Receptor Signaling Pathway
Regulation Of Actin Filament-based Process
Regulation Of Programmed Cell Death
Positive Regulation Of Immune System Process
Insulin Receptor Signaling Pathway
Protein Binding
Natural Killer Cell Mediated Cytotoxicity
Insulin Receptor Substrate Binding
Immune Response-regulating Signaling Pathway
Regulation Of Cytoskeleton Organization
Cadherin Binding
Activation Of Immune Response
Natural Killer Cell Mediated Immunity
Regulation Of Apoptotic Process
Signal Transduction
Protein Kinase Binding
Regulation Protein Catabolic Process At Postsynapse
B Cell Receptor Signaling Pathway
Positive Regulation Of Membrane Tubulation
Vesicle-mediated Transport
Receptor Catabolic Process
Regulation Of Signal Transduction
Import Into Cell
Establishment Of Localization In Cell
Regulation Of Supramolecular Fiber Organization
Receptor Tyrosine Kinase Binding
Positive Regulation Of Cellular Component Biogenesis
Epidermal Growth Factor Receptor Signaling Pathway
T Cell Activation
Viral Budding
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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