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PDCD6 and HEBP2
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid, two hybrid)
HPRD
(two hybrid)
PDCD6
HEBP2
Gene Name
programmed cell death 6
heme binding protein 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Endosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytoplasmic Vesicle
Nuclear Membrane
Extracellular Vesicular Exosome
Endoplasmic Reticulum Exit Site
Cytoplasm
Mitochondrion
Extracellular Vesicular Exosome
Molecular Function
Calcium-dependent Cysteine-type Endopeptidase Activity
Calcium Ion Binding
Protein Binding
Protein Homodimerization Activity
Protein Anchor
Protein Dimerization Activity
Calcium-dependent Protein Binding
Binding, Bridging
Protein Binding
Biological Process
Angiogenesis
Positive Regulation Of Endothelial Cell Proliferation
Proteolysis
Intracellular Protein Transport
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Endothelial Cell Migration
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Negative Regulation Of TOR Signaling
Cellular Response To Heat
Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Response To Calcium Ion
Negative Regulation Of Protein Kinase B Signaling
Apoptotic Signaling Pathway
Negative Regulation Of Mitochondrial Membrane Potential
Positive Regulation Of Necrotic Cell Death
Positive Regulation Of Mitochondrial Membrane Permeability
Regulation Of Response To Reactive Oxygen Species
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
18 interactors:
ANXA11
ANXA7
CDKN2A
CPNE1
CPNE2
CPNE4
FAS
FASLG
HEBP2
IGFALS
MAP3K5
MAPK1IP1L
PDCD6IP
PEF1
SH3KBP1
TIMM22
VPS37C
YWHAQ
2 interactors:
LRPPRC
PDCD6
Entrez ID
10016
23593
HPRD ID
03035
09316
Ensembl ID
ENSG00000249915
Uniprot IDs
O75340
Q53FC3
Q9Y5Z4
PDB IDs
2ZN8
2ZN9
2ZND
2ZNE
2ZRS
2ZRT
3AAJ
3AAK
3R85
3R8J
3R8K
4AYZ
4B0Y
Enriched GO Terms of Interacting Partners
?
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Protein Processing
Activation Of Cysteine-type Endopeptidase Activity
Zymogen Activation
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity
Programmed Cell Death
Positive Regulation Of Cell Death
Positive Regulation Of Endopeptidase Activity
Cell Death
Death
Positive Regulation Of Peptidase Activity
Programmed Necrotic Cell Death
Necrotic Cell Death
Necroptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Response To Inorganic Substance
Membrane Organization
Inflammatory Cell Apoptotic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Proteolysis
Response To Metal Ion
Response To Calcium Ion
Apoptotic Signaling Pathway
T Cell Apoptotic Process
Cell Separation After Cytokinesis
Regulation Of Endopeptidase Activity
Virion Assembly
Regulation Of Peptidase Activity
Necroptotic Process
Regulation Of Cell Death
Negative Regulation Of B Cell Activation
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Proteolysis
Mitochondrial Membrane Organization
Regulation Of Cellular Component Organization
Positive Regulation Of Signal Transduction
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Neuron Death
Regulation Of ERBB Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Motor Neuron Apoptotic Process
Regulation Of Apoptotic Process
Mitochondrion Organization
Cytokinesis, Completion Of Separation
Senescence-associated Heterochromatin Focus Assembly
Endosomal Lumen Acidification
Negative Regulation Of Mitochondrial RNA Catabolic Process
Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway
Regulation Of Mitochondrial Translation
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Mitochondrion Transport Along Microtubule
Establishment Of Mitochondrion Localization
Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Negative Regulation Of TOR Signaling
Mitochondrion Localization
Negative Regulation Of Protein Kinase B Signaling
Intracellular Transport
Organelle Transport Along Microtubule
Positive Regulation Of Endothelial Cell Migration
Regulation Of TOR Signaling
Positive Regulation Of Endothelial Cell Proliferation
Cellular Response To Heat
Positive Regulation Of Epithelial Cell Migration
Regulation Of Cellular Protein Metabolic Process
Regulation Of Endothelial Cell Proliferation
Establishment Of Localization In Cell
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Mitochondrion Organization
Activation Of Cysteine-type Endopeptidase Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Zymogen Activation
Regulation Of Endothelial Cell Migration
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Response To Heat
Response To Calcium Ion
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
MRNA Transport
Positive Regulation Of Cysteine-type Endopeptidase Activity
Regulation Of Protein Kinase B Signaling
Cellular Localization
Positive Regulation Of Angiogenesis
Positive Regulation Of Endopeptidase Activity
Microtubule-based Transport
RNA Transport
Cytoskeleton-dependent Intracellular Transport
Regulation Of Epithelial Cell Migration
Positive Regulation Of Peptidase Activity
RNA Localization
Positive Regulation Of Epithelial Cell Proliferation
Tagcloud
?
adp
bax
bcl
caspase
cdk4
cisplatin
cleavages
define
irradiation
luciferase
ovarian
overexpressing
p16
p21
p27
parp
pdk1
poly
pro
programmed
regulators
ribose
skov
suppressing
tnfalpha
tumorigenesis
uv
xl
Tagcloud (Difference)
?
adp
bax
bcl
caspase
cdk4
cisplatin
cleavages
define
irradiation
luciferase
ovarian
overexpressing
p16
p21
p27
parp
pdk1
poly
pro
programmed
regulators
ribose
skov
suppressing
tnfalpha
tumorigenesis
uv
xl
Tagcloud (Intersection)
?