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SH3KBP1 and ZNF219
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
SH3KBP1
ZNF219
Description
SH3 domain containing kinase binding protein 1
zinc finger protein 219
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Postsynaptic Density
Membrane
Endocytic Vesicle
Cytoplasmic Vesicle Membrane
Cytoplasmic Vesicle
Neuron Projection
Synapse
Anchoring Junction
Glutamatergic Synapse
GABA-ergic Synapse
Nucleus
Nucleoplasm
Membrane
Molecular Function
Protein Binding
SH3 Domain Binding
Ubiquitin Protein Ligase Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Histamine Receptor Activity
Protein Binding
Zinc Ion Binding
Metal Ion Binding
Biological Process
Endocytosis
Apoptotic Process
Cytoskeleton Organization
Actin Filament Organization
Cell-cell Signaling
Regulation Of Cell Shape
Cell Migration
Positive Regulation Of B Cell Activation
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of DNA-templated Transcription
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Chondrocyte Differentiation
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Limb Bud Formation
Pathways
EGFR downregulation
Negative regulation of MET activity
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Reelin signalling pathway
InlB-mediated entry of Listeria monocytogenes into host cell
Potential therapeutics for SARS
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS
Platelet count (
32888494
)
Metabolite levels (
23823483
)
Resting heart rate (
27798624
)
Interacting Genes
59 interacting genes:
ABI2
ANKS1A
ARAP3
ARHGAP27
ASAP1
ASAP2
BCAR1
BLNK
BMPR1B
CAPZA1
CBL
CBLB
CCDC57
CCDC88B
CD2
CYSRT1
DENND2A
EGLN1
GGN
GPRASP3
GRB2
HCK
HIVEP1
INPP5D
ITSN2
KPRP
KRTAP6-3
LZTS2
MVB12A
NEDD4
NELFA
PAK2
PDCD6
PDCD6IP
PIK3CA
PIK3R1
PNMA5
POLR2K
PSMA3
SEPTIN2
SEPTIN6
SH3BP2
SH3GL2
SH3GL3
SH3GLB1
SH3GLB2
SHKBP1
SOS1
SPRY2
STAP1
SYNJ1
TAF6
TJP2
TP53BP2
UBB
UBC
UBE2I
ZBTB7B
ZNF219
17 interacting genes:
AP1M1
ATOSB
BCL2L1
CDK4
CSNK2A2
CTBP1
GRIPAP1
LMO1
MAPK3
MAPK8
SH3GL2
SH3KBP1
SUFU
TRIM41
TTC32
UBASH3A
UFL1
Entrez ID
30011
51222
HPRD ID
02301
05435
Ensembl ID
ENSG00000147010
ENSG00000165804
Uniprot IDs
A0A8V8TNL0
A0A8V8TNT5
A0A8V8TNW8
A0A8V8TP27
A0A8V8TP33
A0A8V8TP40
A0A8V8TP63
A0A8V8TP69
A0A8V8TPM1
A0A8V8TQF6
A0A8V8TQU1
B7Z6E8
Q5JPT2
Q5JPT6
Q96B97
Q9P2Y4
PDB IDs
2BZ8
2K6D
2K9G
2N64
2O2O
2YDL
5ABS
Enriched GO Terms of Interacting Partners
?
SH3 Domain Binding
Cytosol
Phosphotyrosine Residue Binding
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme-linked Receptor Protein Signaling Pathway
Regulation Of ERBB Signaling Pathway
Cytoplasm
Immune Response-activating Cell Surface Receptor Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Antigen Receptor-mediated Signaling Pathway
Regulation Of Cellular Component Organization
Cell Surface Receptor Signaling Pathway
Regulation Of Actin Cytoskeleton Organization
Endocytosis
Regulation Of Actin Filament Organization
Immune Response-activating Signaling Pathway
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of ERBB Signaling Pathway
Insulin-like Growth Factor Receptor Signaling Pathway
Regulation Of Actin Filament-based Process
Regulation Of Programmed Cell Death
Positive Regulation Of Immune System Process
Insulin Receptor Signaling Pathway
Protein Binding
Natural Killer Cell Mediated Cytotoxicity
Insulin Receptor Substrate Binding
Immune Response-regulating Signaling Pathway
Regulation Of Cytoskeleton Organization
Cadherin Binding
Activation Of Immune Response
Natural Killer Cell Mediated Immunity
Regulation Of Apoptotic Process
Signal Transduction
Protein Kinase Binding
Regulation Protein Catabolic Process At Postsynapse
B Cell Receptor Signaling Pathway
Positive Regulation Of Membrane Tubulation
Vesicle-mediated Transport
Receptor Catabolic Process
Regulation Of Signal Transduction
Import Into Cell
Establishment Of Localization In Cell
Regulation Of Supramolecular Fiber Organization
Receptor Tyrosine Kinase Binding
Positive Regulation Of Cellular Component Biogenesis
Epidermal Growth Factor Receptor Signaling Pathway
T Cell Activation
Viral Budding
Regulation Of Autophagy
Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Macroautophagy
Glutamatergic Synapse
Endocytosis
Negative Regulation Of Proteolysis Involved In Protein Catabolic Process
Negative Regulation Of T Cell Mediated Immune Response To Tumor Cell
Negative Regulation Of Immune Response To Tumor Cell
Regulation Of T Cell Mediated Immune Response To Tumor Cell
MAP Kinase Activity
Synapse
Regulation Of Protein Localization
Response To Lipopolysaccharide
Positive Regulation Of Cyclase Activity
Stress-activated MAPK Cascade
NLRP3 Inflammasome Complex Assembly
Negative Regulation Of Signal Transduction
Import Into Cell
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Cytosol
Response To Molecule Of Bacterial Origin
Protein Serine Kinase Activity
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Proteolysis
Regulation Of Response To Tumor Cell
Stress-activated Protein Kinase Signaling Cascade
Negative Regulation Of Catabolic Process
Regulation Of Proteolysis
Canonical Inflammasome Complex Assembly
Protein Serine/threonine Kinase Activity
Positive Regulation Of Establishment Of Protein Localization To Mitochondrion
Negative Regulation Of T Cell Mediated Immunity
Regulation Of Immune System Process
Cellular Response To Lipopolysaccharide
Synaptic Vesicle Endocytosis
Vesicle-mediated Transport
DNA Damage Response
Negative Regulation Of Metabolic Process
Apoptotic Process In Bone Marrow Cell
Cellular Response To Molecule Of Bacterial Origin
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Presynaptic Endocytosis
DNA-binding Transcription Factor Binding
JUN Phosphorylation
UFM1 Ligase Activity
Regulation Of Cellular Response To Drug
Positive Regulation Of Cellular Response To Drug
Extrinsic Component Of Postsynaptic Early Endosome Membrane
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Tagcloud (Intersection)
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