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PDCD6 and CPNE2
Number of citations of the paper that reports this interaction (PMID
12522145
)
20
Data Source:
HPRD
(two hybrid)
PDCD6
CPNE2
Gene Name
programmed cell death 6
copine II
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Endosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytoplasmic Vesicle
Nuclear Membrane
Extracellular Vesicular Exosome
Endoplasmic Reticulum Exit Site
Extracellular Vesicular Exosome
Molecular Function
Calcium-dependent Cysteine-type Endopeptidase Activity
Calcium Ion Binding
Protein Binding
Protein Homodimerization Activity
Protein Anchor
Protein Dimerization Activity
Calcium-dependent Protein Binding
Binding, Bridging
Biological Process
Angiogenesis
Positive Regulation Of Endothelial Cell Proliferation
Proteolysis
Intracellular Protein Transport
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Endothelial Cell Migration
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Negative Regulation Of TOR Signaling
Cellular Response To Heat
Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Response To Calcium Ion
Negative Regulation Of Protein Kinase B Signaling
Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
18 interactors:
ANXA11
ANXA7
CDKN2A
CPNE1
CPNE2
CPNE4
FAS
FASLG
HEBP2
IGFALS
MAP3K5
MAPK1IP1L
PDCD6IP
PEF1
SH3KBP1
TIMM22
VPS37C
YWHAQ
18 interactors:
ACTB
ANXA7
BCOR
CDKN1A
IKBKG
LNX1
MYCBP
PDCD6
PPP5C
RDX
REL
SKIL
SORBS3
TERF2IP
TRIM27
UBA3
UBE2M
UBE2O
Entrez ID
10016
221184
HPRD ID
03035
05015
Ensembl ID
ENSG00000249915
ENSG00000140848
Uniprot IDs
O75340
Q53FC3
Q96FN4
PDB IDs
2ZN8
2ZN9
2ZND
2ZNE
2ZRS
2ZRT
3AAJ
3AAK
Enriched GO Terms of Interacting Partners
?
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Protein Processing
Activation Of Cysteine-type Endopeptidase Activity
Zymogen Activation
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity
Programmed Cell Death
Positive Regulation Of Cell Death
Positive Regulation Of Endopeptidase Activity
Cell Death
Death
Positive Regulation Of Peptidase Activity
Programmed Necrotic Cell Death
Necrotic Cell Death
Necroptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Response To Inorganic Substance
Membrane Organization
Inflammatory Cell Apoptotic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Proteolysis
Response To Metal Ion
Response To Calcium Ion
Apoptotic Signaling Pathway
T Cell Apoptotic Process
Cell Separation After Cytokinesis
Regulation Of Endopeptidase Activity
Virion Assembly
Regulation Of Peptidase Activity
Necroptotic Process
Regulation Of Cell Death
Negative Regulation Of B Cell Activation
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Proteolysis
Mitochondrial Membrane Organization
Regulation Of Cellular Component Organization
Positive Regulation Of Signal Transduction
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Neuron Death
Regulation Of ERBB Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Motor Neuron Apoptotic Process
Regulation Of Apoptotic Process
Mitochondrion Organization
Cytokinesis, Completion Of Separation
Senescence-associated Heterochromatin Focus Assembly
Endosomal Lumen Acidification
Protein Modification By Small Protein Conjugation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Intracellular Signal Transduction
Protein Neddylation
Positive Regulation Of Signal Transduction
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Gene Expression
Regulation Of Cellular Component Organization
Protein Ubiquitination
Regulation Of Cellular Process
Transcription, DNA-templated
Regulation Of Intracellular Signal Transduction
RNA Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Innate Immune Response
Protein Oligomerization
Protein K63-linked Ubiquitination
Protein Trimerization
Response To Stress
NIK/NF-kappaB Signaling
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Organelle Organization
Protein Monoubiquitination
Regulation Of Signal Transduction
Cellular Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Epithelial Cell Differentiation
Regulation Of Cell Death
Negative Regulation Of Histone H3-K36 Methylation
Negative Regulation Of DNA Recombination At Telomere
Positive Regulation Of Programmed Cell Death
I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Signaling
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Cell Death
Fc Receptor Signaling Pathway
Negative Regulation Of Nucleic Acid-templated Transcription
Cellular Response To Heat
Lymphocyte Homeostasis
Retrograde Transport, Endosome To Golgi
Negative Regulation Of RNA Biosynthetic Process
RNA Metabolic Process
Regulation Of Neuron Death
Cellular Protein Modification Process
Negative Regulation Of Tooth Mineralization
Negative Regulation Of Interleukin-2 Secretion
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud
?
adp
bax
bcl
caspase
cdk4
cisplatin
cleavages
define
irradiation
luciferase
ovarian
overexpressing
p16
p21
p27
parp
pdk1
poly
pro
programmed
regulators
ribose
skov
suppressing
tnfalpha
tumorigenesis
uv
xl
Tagcloud (Difference)
?
adp
bax
bcl
caspase
cdk4
cisplatin
cleavages
define
irradiation
luciferase
ovarian
overexpressing
p16
p21
p27
parp
pdk1
poly
pro
programmed
regulators
ribose
skov
suppressing
tnfalpha
tumorigenesis
uv
xl
Tagcloud (Intersection)
?