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SH3KBP1 and ZBTB7B
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SH3KBP1
ZBTB7B
Gene Name
SH3-domain kinase binding protein 1
zinc finger and BTB domain containing 7B
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Cytoskeleton
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Cytoplasmic Vesicle Membrane
Neuron Projection
Synapse
Nucleus
Nucleoplasm
Molecular Function
Protein Binding
SH3 Domain Binding
DNA Binding
Metal Ion Binding
Biological Process
Endocytosis
Apoptotic Process
Cytoskeleton Organization
Epidermal Growth Factor Receptor Signaling Pathway
Cell-cell Signaling
Regulation Of Cell Shape
Cell Migration
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Multicellular Organismal Development
Ectoderm Development
Cell Differentiation
Pathways
Signaling by the B Cell Receptor (BCR)
Signaling by EGFR
EGFR downregulation
Signaling by EGFR in Cancer
Signaling by Ligand-Responsive EGFR Variants in Cancer
Signaling by Overexpressed Wild-Type EGFR in Cancer
Signaling by EGFRvIII in Cancer
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Adaptive Immune System
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Protein-Protein Interactions
45 interactors:
ABI2
ARAP1
ARHGAP27
ASAP1
ASAP2
BCAR1
BLNK
BMPR1B
CAPZA1
CBL
CBLB
CD2
GRB2
HCK
INPP5D
ITSN2
LMNA
MVB12A
NEDD4
PAK2
PDCD6
PDCD6IP
PIK3CA
PIK3R1
PNMA5
PSMA3
SH3BP2
SH3GL2
SH3GL3
SH3GLB1
SH3GLB2
SHKBP1
SOS1
SPRY2
STAP1
SUMO1
SUMO2
SUMO3
SYNJ1
TAF6
TJP2
UBB
UBC
ZBTB7B
ZNF219
17 interactors:
BCL6
EP300
GRAP2
GRB2
IMP4
KPNA2
MORF4L2
NCK2
NDN
PIN1
RPL9
SH3KBP1
SH3YL1
SORBS3
SYTL4
ZBTB5
ZNF277
Entrez ID
30011
51043
HPRD ID
02301
09625
Ensembl ID
ENSG00000147010
ENSG00000160685
Uniprot IDs
B7Z6E8
Q5JPT6
Q96B97
O15156
PDB IDs
2BZ8
2K6D
2K9G
2O2O
2YDL
Enriched GO Terms of Interacting Partners
?
Regulation Of Signal Transduction
Regulation Of Signaling
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of ERBB Signaling Pathway
Regulation Of Cellular Process
Signaling
Signal Transduction
Cell Communication
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
T Cell Receptor Signaling Pathway
Cellular Response To Fibroblast Growth Factor Stimulus
Immune Response-activating Cell Surface Receptor Signaling Pathway
Response To Fibroblast Growth Factor
Regulation Of Apoptotic Process
Positive Regulation Of Signal Transduction
Cell Surface Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Protein Catabolic Process
Regulation Of Cell Death
Antigen Receptor-mediated Signaling Pathway
Neurotrophin Signaling Pathway
Immune Response-regulating Signaling Pathway
Apoptotic Process
Immune System Process
Programmed Cell Death
Cellular Response To Stimulus
Cell Death
Death
Fc Receptor Signaling Pathway
Immune Response
Viral Process
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Metabolic Process
Leukocyte Migration
Fc-epsilon Receptor Signaling Pathway
Endocytosis
Locomotion
Movement Of Cell Or Subcellular Component
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Catalytic Activity
Regulation Of Immune Response
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Regulation Of T Cell Activation
Positive Regulation Of Cell Activation
Regulation Of Signaling
Regulation Of Cell-cell Adhesion
Regulation Of Cellular Senescence
Regulation Of Lymphocyte Activation
Positive Regulation Of Organelle Organization
Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Cellular Component Organization
ERBB Signaling Pathway
Regulation Of Cell Activation
Regulation Of Signal Transduction
Regulation Of Organelle Organization
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Ras Protein Signal Transduction
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Viral Process
Negative Regulation Of ERBB Signaling Pathway
Regulation Of Protein Deacetylation
Positive Regulation Of Cell-cell Adhesion
Cell Surface Receptor Signaling Pathway
RNA Biosynthetic Process
Histone H2B Acetylation
RNA Metabolic Process
Regulation Of Cell Adhesion
Regulation Of DNA Recombination
Negative Regulation Of Signaling
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cellular Process
Positive Regulation Of Cellular Component Biogenesis
T Cell Costimulation
Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation
Cellular Response To Stimulus
Immune Response
Regulation Of Immune System Process
Establishment Of Protein Localization To Organelle
Nucleobase-containing Compound Metabolic Process
Defense Response
Regulation Of Actin Cytoskeleton Organization
Innate Immune Response
Positive Regulation Of Cell Adhesion
Negative Regulation Of Mast Cell Cytokine Production
N-terminal Peptidyl-lysine Acetylation
Negative Regulation Of Isotype Switching To IgE Isotypes
Cell Migration
Tagcloud
?
calm3
cblb
ccna2
ccnd3
cdk6
cited1
dems
dok
elk3
fyn
git1
hck
lck
module
modules
nonmodule
p85beta
pdgfra
pib5pa
psd93
ptch2
sam68
shc
tgfbr1
tgfbr2
vav2
wilcoxon
yes
zfyve9
Tagcloud (Difference)
?
calm3
cblb
ccna2
ccnd3
cdk6
cited1
dems
dok
elk3
fyn
git1
hck
lck
module
modules
nonmodule
p85beta
pdgfra
pib5pa
psd93
ptch2
sam68
shc
tgfbr1
tgfbr2
vav2
wilcoxon
yes
zfyve9
Tagcloud (Intersection)
?