SFI1 and CCDC57

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SFI1	CCDC57
Gene Name		Sfi1 homolog, spindle assembly associated (yeast)	coiled-coil domain containing 57
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Centriole Cytosol
	Molecular Function	Protein Binding Phosphatase Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Negative Regulation Of Phosphatase Activity
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CCDC120 CCDC57 CETN2 CRX FAM131C GCSH KRT19 LPXN MAD2L2 MDFI RADIL SERTAD1	42 interactors: AES AQP1 ARL4A CBX8 CCDC120 CDC20B CEP57L1 CWF19L2 FAM161A FAM50B FAM90A1 GPKOW HAUS1 HBA2 KIAA0368 LENG1 LINC00526 MFAP1 NAPRT NELFE NUMA1 PER1 PPHLN1 PPP1R18 PRAM1 PRPF31 PRR3 PTPN7 RAB3IL1 ROBO3 SFI1 SIRPA TBC1D22B TMEM100 TSGA10IP USP15 USP2 UTP14C ZFC3H1 ZGPAT ZMAT2 ZNF417
Entrez ID		9814	284001
HPRD ID		11550	14150
Ensembl ID		ENSG00000198089	ENSG00000176155
Uniprot IDs		A8K8P3	Q2TAC2
PDB IDs		2K2I
Enriched GO Terms of Interacting Partners?		Cell Differentiation Involved In Embryonic Placenta Development Negative Regulation Of DNA Binding Glycine Decarboxylation Via Glycine Cleavage System Positive Regulation Of Photoreceptor Cell Differentiation Regulation Of DNA Binding Negative Regulation Of Binding Embryonic Placenta Development	Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Transcription From RNA Polymerase II Promoter Photoperiodism Entrainment Of Circadian Clock Bicarbonate Transport Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Nicotinate Nucleotide Salvage
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