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CCDC57 and NAPRT
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CCDC57
NAPRT
Gene Name
coiled-coil domain containing 57
nicotinate phosphoribosyltransferase
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Nicotinate-nucleotide Diphosphorylase (carboxylating) Activity
Nicotinate Phosphoribosyltransferase Activity
Ligase Activity
Biological Process
Vitamin Metabolic Process
Water-soluble Vitamin Metabolic Process
Nicotinamide Metabolic Process
Response To Oxidative Stress
NAD Biosynthetic Process
Nicotinate Nucleotide Salvage
NAD Metabolic Process
Small Molecule Metabolic Process
Pathways
Metabolism of vitamins and cofactors
Defective CD320 causes methylmalonic aciduria
Defective GIF causes intrinsic factor deficiency
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective HLCS causes multiple carboxylase deficiency
Defective MMAB causes methylmalonic aciduria type cblB
Defective BTD causes biotidinase deficiency
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective MMAA causes methylmalonic aciduria type cblA
Defective CUBN causes hereditary megaloblastic anemia 1
Defective AMN causes hereditary megaloblastic anemia 1
Defective MUT causes methylmalonic aciduria mut type
Nicotinamide salvaging
Metabolism of water-soluble vitamins and cofactors
Defects in biotin (Btn) metabolism
Defective TCN2 causes hereditary megaloblastic anemia
Nicotinate metabolism
Defects in cobalamin (B12) metabolism
Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions
42 interactors:
AES
AQP1
ARL4A
CBX8
CCDC120
CDC20B
CEP57L1
CWF19L2
FAM161A
FAM50B
FAM90A1
GPKOW
HAUS1
HBA2
KIAA0368
LENG1
LINC00526
MFAP1
NAPRT
NELFE
NUMA1
PER1
PPHLN1
PPP1R18
PRAM1
PRPF31
PRR3
PTPN7
RAB3IL1
ROBO3
SFI1
SIRPA
TBC1D22B
TMEM100
TSGA10IP
USP15
USP2
UTP14C
ZFC3H1
ZGPAT
ZMAT2
ZNF417
5 interactors:
CCDC57
EHMT2
GRAMD3
KRT40
RBPMS
Entrez ID
284001
93100
HPRD ID
14150
15161
Ensembl ID
ENSG00000176155
ENSG00000147813
Uniprot IDs
Q2TAC2
Q6XQN6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Entrainment Of Circadian Clock By Photoperiod
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Photoperiodism
Entrainment Of Circadian Clock
Bicarbonate Transport
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Maintenance Of Symbiont-containing Vacuole By Host
Transepithelial Water Transport
Nicotinate Nucleotide Salvage
DNA Methylation On Cytosine Within A CG Sequence
Histone H3-K27 Methylation
Peptidyl-lysine Dimethylation
DNA Methylation On Cytosine
Positive Regulation Of SMAD Protein Import Into Nucleus
Regulation Of SMAD Protein Import Into Nucleus
Histone H3-K9 Methylation
Synaptonemal Complex Assembly
Synaptonemal Complex Organization
Histone H3-K9 Modification
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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