SFI1 and CETN2

Number of citations of the paper that reports this interaction (PubMedID 14504268)
72

Data Source:
HPRD (in vitro)

		SFI1	CETN2
Description		SFI1 centrin binding protein	centrin 2
Image
GO Annotations	Cellular Component	Cytoplasm Centriole Cytosol Cytoskeleton	Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Nuclear Pore Nuclear Basket Apical Part Of Cell Transcription Export Complex 2 XPC Complex Glial Cell Projection 9+2 Motile Cilium
	Molecular Function	Protein Binding Phosphatase Binding	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding Metal Ion Binding
	Biological Process		Microtubule Cytoskeleton Organization Mitotic Cell Cycle DNA Repair Nucleotide-excision Repair DNA Damage Response Centriole Replication Spermatogenesis Protein Transport Regulation Of Cytokinesis MRNA Transport Cell Division
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Regulation of PLK1 Activity at G2/M Transition SUMOylation of DNA damage response and repair proteins Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER AURKA Activation by TPX2
Drugs
Diseases
GWAS		A body shape index ( 34021172) Age-related hearing impairment ( 24939585) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Fish- and plant-related diet ( 32066663) Lymphocyte count ( 32888494) Metabolite levels ( 23823483) Neutrophil percentage of white cells ( 32888494) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Type 2 diabetes ( 31118516)	Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		15 interacting genes: CCDC120 CCDC57 CETN2 CRX FAM131C GCSH GOLGA2 KRT19 LPXN MAD2L2 MDFI PPP1CA RADIL RBPMS SERTAD1	7 interacting genes: ARSA CCP110 PNMA5 PRMT6 SFI1 UBC XPC
Entrez ID		9814	1069
HPRD ID		11550	02051
Ensembl ID		ENSG00000198089	ENSG00000147400
Uniprot IDs		A8K8P3	P41208
PDB IDs		2K2I	1M39 1ZMZ 2A4J 2GGM 2K2I 2OBH 8EBS 8EBT 8EBV 8EBW 8EBX 8J07
Enriched GO Terms of Interacting Partners?		Microtubule Organizing Center Organization Telomere Maintenance In Response To DNA Damage Centriole Replication Cell Differentiation Involved In Embryonic Placenta Development Centriole Assembly Centriole Microtubule Nucleation Microtubule Cytoskeleton Organization Cell Division
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