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SFI1

Gene Name Sfi1 homolog, spindle assembly associated (yeast)
Image
Gene Ontology Annotations Cellular Component
  • Centriole
  • Cytosol
Molecular Function
  • Protein Binding
  • Phosphatase Binding
Biological Process
  • G2/M Transition Of Mitotic Cell Cycle
  • Mitotic Cell Cycle
  • Organelle Organization
  • Negative Regulation Of Phosphatase Activity
Pathways
  • Organelle biogenesis and maintenance
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Loss of Nlp from mitotic centrosomes
  • G2/M Transition
  • Assembly of the primary cilium
  • Centrosome maturation
  • Regulation of PLK1 Activity at G2/M Transition
  • Mitotic G2-G2/M phases
  • Anchoring of the basal body to the plasma membrane
  • Recruitment of mitotic centrosome proteins and complexes
  • Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-protein Interactions 12 interactors: CCDC120 CCDC57 CETN2 CRX FAM131C GCSH KRT19 LPXN MAD2L2 MDFI RADIL SERTAD1
Entrez ID 9814
HPRD ID 11550
Ensembl ID ENSG00000198089
Uniprot IDs A8K8P3
PDB IDs 2K2I
Enriched GO Terms of Interacting Partners?
  • Cell Differentiation Involved In Embryonic Placenta Development
  • Negative Regulation Of DNA Binding
  • Glycine Decarboxylation Via Glycine Cleavage System
  • Positive Regulation Of Photoreceptor Cell Differentiation
  • Regulation Of DNA Binding
  • Negative Regulation Of Binding
  • Embryonic Placenta Development
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