SFI1 and RADIL

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		SFI1	RADIL
Gene Name		Sfi1 homolog, spindle assembly associated (yeast)	Ras association and DIL domains
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Gene Ontology Annotations	Cellular Component	Centriole Cytosol	Microtubule
	Molecular Function	Protein Binding Phosphatase Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Negative Regulation Of Phosphatase Activity	Signal Transduction Multicellular Organismal Development Substrate Adhesion-dependent Cell Spreading
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		12 interactors: CCDC120 CCDC57 CETN2 CRX FAM131C GCSH KRT19 LPXN MAD2L2 MDFI RADIL SERTAD1	13 interactors: ASCC2 CEP76 FGFR3 GATA1 KRT31 LITAF MAGEA11 MED19 MRFAP1L1 RHOXF2 SFI1 USP7 YWHAB
Entrez ID		9814	55698
HPRD ID		11550	07663
Ensembl ID		ENSG00000198089	ENSG00000157927
Uniprot IDs		A8K8P3	F5H6X3 Q96JH8
PDB IDs		2K2I	1UM1 3EC8
Enriched GO Terms of Interacting Partners?		Cell Differentiation Involved In Embryonic Placenta Development Negative Regulation Of DNA Binding Glycine Decarboxylation Via Glycine Cleavage System Positive Regulation Of Photoreceptor Cell Differentiation Regulation Of DNA Binding Negative Regulation Of Binding Embryonic Placenta Development	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Dephosphorylation Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Regulation Of Metabolic Process Basophil Differentiation Eosinophil Fate Commitment G2/M Transition Of Mitotic Cell Cycle Eosinophil Differentiation Transcriptional Activation By Promoter-enhancer Looping Regulation Of Dephosphorylation Cellular Response To Hormone Stimulus Insulin Receptor Signaling Pathway Regulation Of Definitive Erythrocyte Differentiation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Negative Regulation Of Protein Dephosphorylation Alveolar Secondary Septum Development Negative Regulation Of Protein Transport Axonogenesis Involved In Innervation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Phosphorus Metabolic Process Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Maintenance Of DNA Methylation Cell Morphogenesis Involved In Differentiation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Regulation Of Peptidyl-tyrosine Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Chondrocyte Proliferation Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway MAPK Cascade Cellular Response To Thyroid Hormone Stimulus Positive Regulation Of Osteoblast Proliferation Positive Regulation Of Intracellular Signal Transduction Regulation Of Centriole Replication Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Regulation Of Cellular Process Mitotic Cell Cycle Phase Transition Positive Regulation Of Phosphorylation Cell Cycle Phase Transition
Tagcloud ?			adhesion adhesiveness associates concurrent dynamics effector effectors emerging focal gtpase influences inside integrin kif14 kinesin mediate microtubules migration negatively optimal pdz polarity rap rap1 reach regulates spreading tethering thereby
Tagcloud (Difference) ?			adhesion adhesiveness associates concurrent dynamics effector effectors emerging focal gtpase influences inside integrin kif14 kinesin mediate microtubules migration negatively optimal pdz polarity rap rap1 reach regulates spreading tethering thereby
Tagcloud (Intersection) ?