CCDC57 and ABLIM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC57	ABLIM1
Description		coiled-coil domain containing 57	actin binding LIM protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Spindle Cytoskeleton Spindle Microtubule Centriolar Satellite	Stress Fiber Cytoplasm Cytoskeleton Postsynaptic Density Actin Cytoskeleton Lamellipodium
	Molecular Function	Protein Binding	Actin Binding Protein Binding Metal Ion Binding Actin Filament Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Microtubule Nucleation Centriole Replication Positive Regulation Of Mitotic Cell Cycle Cilium Assembly	Transcription By RNA Polymerase II Cytoskeleton Organization Axon Guidance Visual Perception Animal Organ Morphogenesis Lamellipodium Assembly Positive Regulation Of Transcription By RNA Polymerase II Cilium Assembly
Pathways			DCC mediated attractive signaling
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)	Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Taste perception (total score including 6-n-propylthiouracil) in obesity with metabolic syndrome ( 31005965)
Interacting Genes		148 interacting genes: ABI1 ABI2 ABLIM1 AMOTL2 ANKRD23 AQP1 ARID5A ARL4A AXIN1 BCAR3 BEX2 C19orf44 CATSPERT CBX8 CBY2 CCDC120 CCDC33 CDC20B CEP57L1 CFAP53 COIL CRTC2 CWF19L2 DCLK2 DISC1 DTX2 ECPAS EFHC2 EIF3D EIF4G1 ELOA EMILIN3 ESS2 FAM107A FAM161A FAM161B FAM228A FAM50B FAM90A1 FH FOXD4L1 FTO GFAP GIGYF1 GPBP1 GPKOW GRPEL1 HAUS1 HBA2 HDX IHO1 IKZF3 INCA1 INTS2 JRK KANK2 KIAA0408 KLF1 KLF15 KPRP KRT4 KRT76 KRTAP13-2 KRTAP13-3 LENG1 LINC00526 LZTS1 MAD1L1 MDM1 MFAP1 MT1E MYOZ3 NAB2 NAPRT NCOA5 NELFE NME4 NUMA1 PAK5 PER1 POM121 PPHLN1 PPP1R18 PRAM1 PRDM6 PROSER3 PRPF18 PRPF31 PRR3 PSMB4 PTCHD3 PTPN7 RAB3IL1 RASD1 RBM48 RDM1 RINT1 RNF6 ROBO3 RUSC1 RXRB SAXO4 SFI1 SH3KBP1 SHISA6 SIRPA SLC25A48 SMG9 SNRNP35 SORBS3 SPMIP2 SPMIP6 SPRY1 SYT6 TBC1D22B TCP10L TFIP11 TFPT TIMM44 TLE5 TMEM100 TNNI1 TP53BP2 TRIM14 TRIM29 TSEN54 TSGA10IP TSHZ2 TXLNA USP15 USP2 UTP14C VPS52 YJU2 ZBTB4 ZC2HC1C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF436 ZNF474 ZNF552 ZNF648 ZNF655 ZNF688 ZNF835 ZSWIM3	27 interacting genes: ACTB ACTG1 APP BEGAIN CALCOCO2 CARD9 CCDC57 DAPK1 FHL2 GOLGA2 HOOK2 HSF2BP HUNK KCNJ12 KLHL20 KRT15 LDOC1 LRRK2 MFHAS1 PTPRD SREBF2 TRAF2 TSC22D4 TTN USHBP1 VIM YWHAG
Entrez ID		284001	3983
HPRD ID		14150	03819
Ensembl ID		ENSG00000176155	ENSG00000099204
Uniprot IDs		A0A590UJT6 Q2TAC2	A0A9L9PY99 B3KSG3 B4DQA3 B7Z4H1 O14639
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Spliceosomal Complex Nucleus Cytoskeleton MRNA Splicing, Via Spliceosome RNA Splicing Axonemal A Tubule Inner Sheath RNA Splicing, Via Transesterification Reactions	Identical Protein Binding Response To Muramyl Dipeptide Cytoskeleton Regulation Of Synaptic Vesicle Endocytosis Cytoskeleton Organization Regulation Of Synaptic Vesicle Recycling Regulation Of Transepithelial Transport Cytoplasm Structural Constituent Of Cytoskeleton Response To Type II Interferon Dense Body Axon Morphogenesis Of A Polarized Epithelium Cellular Response To Oxygen-containing Compound Structural Constituent Of Postsynaptic Actin Cytoskeleton Actin Cytoskeleton Regulation Of JNK Cascade Cellular Response To Manganese Ion Cellular Response To Muramyl Dipeptide Response To Cytokine Response To Peptide Cellular Response To Type II Interferon Response To Manganese Ion Protein Homooligomerization Intracellular Signal Transduction Regulation Of Autophagy Postsynaptic Actin Cytoskeleton Organization Golgi-associated Vesicle Phagocytic Vesicle Protein Localization To Cell-cell Junction Calyx Of Held Synapse Regulation Of Protein Localization Positive Regulation Of Gene Expression Protein Tetramerization Regulation Of Amyloid-beta Clearance Regulation Of Calcium-mediated Signaling Cellular Response To Catecholamine Stimulus Response To Catecholamine Syntaxin-1 Binding Focal Adhesion Postsynaptic Cytoskeleton Organization Schaffer Collateral - CA1 Synapse Positive Regulation Of JNK Cascade Cellular Component Assembly Protein Kinase Binding Protein Complex Oligomerization Positive Regulation Of MAPK Cascade Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production
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