GPRASP1 and OXTR

Number of citations of the paper that reports this interaction (PubMedID 15452121)
0

Data Source:
HPRD (in vitro)

		GPRASP1	OXTR
Description		G protein-coupled receptor associated sorting protein 1	oxytocin receptor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Plasma Membrane Membrane
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Oxytocin Receptor Activity Vasopressin Receptor Activity
	Biological Process	Endosome To Lysosome Transport G Protein-coupled Receptor Catabolic Process	Regulation Of Systemic Arterial Blood Pressure By Vasopressin System Process Muscle Contraction Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Female Pregnancy Lactation Cellular Response To Hormone Stimulus Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Maternal Process Involved In Parturition Regulation Of Biological Quality Positive Regulation Of Cold-induced Thermogenesis
Pathways			Vasopressin-like receptors G alpha (q) signalling events
Drugs			Vasopressin Oxytocin Carbetocin Atosiban Relcovaptan
Diseases
GWAS			Caudate activity during reward ( 28927378) Chronotype ( 30696823) Depression and alcohol dependence ( 22064162) Liver fibrosis severity in HIV/hepatitis C co-infection ( 27339598) Morning person ( 30696823)
Interacting Genes		48 interacting genes: ADRB1 ADRB2 AGTR1 ATXN7 C8orf33 CALCR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRIP1 CXCR2 DSCAM F2R F2RL1 GLP1R GLYAT GRM1 GRM5 GRM8 HGH1 HMOX2 HTR7 LAMTOR5 LRP2 MAP7D1 MLNR MTF2 OFD1 OPRD1 OPRK1 OPRL1 OPRM1 OXTR PBK PER1 PFDN1 SNAPIN STMN2 TAC3 TACR1 TACR2 TACR3 TBXA2R TFG TRAF4 VIPR1	18 interacting genes: ALAS1 ARRB2 ASH1L AVP CD81 CYFIP2 EMC10 FSCN1 GPRASP1 LCNL1 MVB12A OXT PSMA7 SIRT2 THOC5 TMEM161A TSPAN7 YIPF3
Entrez ID		9737	5021
HPRD ID		02333	01328
Ensembl ID		ENSG00000198932	ENSG00000180914
Uniprot IDs		Q5JY77	B2R9L7 P30559
PDB IDs			6TPK 7QVM 7RYC
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger G Protein-coupled Acetylcholine Receptor Activity Regulation Of Blood Pressure Signal Transduction Regulation Of Smooth Muscle Contraction Trans-synaptic Signaling System Process Synaptic Signaling G Protein-coupled Peptide Receptor Activity Regulation Of System Process G Protein-coupled Acetylcholine Receptor Signaling Pathway Postsynaptic Membrane Chemical Synaptic Transmission Vascular Process In Circulatory System Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Blood Pressure Dendrite Blood Vessel Diameter Maintenance Regulation Of Tube Size Circulatory System Process G Protein-coupled Opioid Receptor Activity Acetylcholine Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Postsynaptic Signal Transduction Positive Regulation Of Muscle Contraction Plasma Membrane G Protein-coupled Opioid Receptor Signaling Pathway Cell-cell Signaling Positive Regulation Of Cytosolic Calcium Ion Concentration Smooth Muscle Contraction Signaling Regulation Of Biological Quality Positive Regulation Of Flagellated Sperm Motility Tachykinin Receptor Activity Cell Communication Regulation Of Muscle Contraction Positive Regulation Of Cilium Movement Regulation Of Blood Circulation Regulation Of Flagellated Sperm Motility Regulation Of Systemic Arterial Blood Pressure Regulation Of MAPK Cascade Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Muscle System Process Positive Regulation Of MAPK Cascade	Neurohypophyseal Hormone Activity Maternal Aggressive Behavior Regulation Of Female Receptivity Female Mating Behavior Aggressive Behavior Maternal Behavior Grooming Behavior Parental Behavior Receptor Catabolic Process Mating Behavior Neuronal Dense Core Vesicle Positive Regulation Of Fatty Acid Biosynthetic Process Neuropeptide Hormone Activity Positive Regulation Of Blood Pressure Regulation Of Fatty Acid Biosynthetic Process Response To Electrical Stimulus Reproductive Behavior V1B Vasopressin Receptor Binding Positive Regulation Of Fatty Acid Metabolic Process Macrophage Fusion Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Positive Regulation Of Hindgut Contraction Oxytocin Receptor Binding Receptor Metabolic Process Negative Regulation Of Oligodendrocyte Progenitor Proliferation Cellular Response To Caloric Restriction Tarsal Gland Development Uterine Gland Development
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