OXTR and YIPF3

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		OXTR	YIPF3
Description		oxytocin receptor	Yip1 domain family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Cytoplasm Golgi Apparatus Plasma Membrane Membrane Transport Vesicle
	Molecular Function	G Protein-coupled Receptor Activity Oxytocin Receptor Activity Vasopressin Receptor Activity	Protein Binding
	Biological Process	Regulation Of Systemic Arterial Blood Pressure By Vasopressin System Process Muscle Contraction Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Female Pregnancy Lactation Cellular Response To Hormone Stimulus Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Maternal Process Involved In Parturition Regulation Of Biological Quality Positive Regulation Of Cold-induced Thermogenesis	Cell Differentiation
Pathways		Vasopressin-like receptors G alpha (q) signalling events
Drugs		Vasopressin Oxytocin Carbetocin Atosiban Relcovaptan
Diseases
GWAS		Caudate activity during reward ( 28927378) Chronotype ( 30696823) Depression and alcohol dependence ( 22064162) Liver fibrosis severity in HIV/hepatitis C co-infection ( 27339598) Morning person ( 30696823)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		18 interacting genes: ALAS1 ARRB2 ASH1L AVP CD81 CYFIP2 EMC10 FSCN1 GPRASP1 LCNL1 MVB12A OXT PSMA7 SIRT2 THOC5 TMEM161A TSPAN7 YIPF3	23 interacting genes: CHRM3 CHRM4 DRD2 HOXA1 HRH1 INCA1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP3-2 KRTAP5-9 KRTAP9-4 KRTAP9-8 MC4R NOTCH2NLA OPRM1 OXTR PLSCR1 TRIM42 YIPF4
Entrez ID		5021	25844
HPRD ID		01328	09852
Ensembl ID		ENSG00000180914	ENSG00000137207
Uniprot IDs		B2R9L7 P30559	Q5JTD5 Q9GZM5
PDB IDs		6TPK 7QVM 7RYC
Enriched GO Terms of Interacting Partners?		Neurohypophyseal Hormone Activity Maternal Aggressive Behavior Regulation Of Female Receptivity Female Mating Behavior Aggressive Behavior Maternal Behavior Grooming Behavior Parental Behavior Receptor Catabolic Process Mating Behavior Neuronal Dense Core Vesicle Positive Regulation Of Fatty Acid Biosynthetic Process Neuropeptide Hormone Activity Positive Regulation Of Blood Pressure Regulation Of Fatty Acid Biosynthetic Process Response To Electrical Stimulus Reproductive Behavior V1B Vasopressin Receptor Binding Positive Regulation Of Fatty Acid Metabolic Process Macrophage Fusion Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Positive Regulation Of Hindgut Contraction Oxytocin Receptor Binding Receptor Metabolic Process Negative Regulation Of Oligodendrocyte Progenitor Proliferation Cellular Response To Caloric Restriction Tarsal Gland Development Uterine Gland Development	Intermediate Filament Keratin Filament Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger G Protein-coupled Acetylcholine Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Activity Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Acetylcholine Receptor Signaling Pathway Postsynaptic Signal Transduction G Protein-coupled Receptor Signaling Pathway Visual Behavior Behavioral Response To Ethanol Response To Histamine Regulation Of Behavior Negative Regulation Of Cytosolic Calcium Ion Concentration Response To Morphine Dendrite Neuropeptide Binding Positive Regulation Of Vasoconstriction G-protein Alpha-subunit Binding Chemical Synaptic Transmission Trans-synaptic Signaling Synaptic Signaling Semicircular Canal Formation Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Oxytocin Receptor Activity
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