GPRASP1 and STMN2

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		GPRASP1	STMN2
Name		G protein-coupled receptor associated sorting protein 1	stathmin 2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Cytoplasm Endosome Golgi Apparatus Cytosol Membrane Lamellipodium Axon Growth Cone Cell Projection Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Tubulin Binding Calcium-dependent Protein Binding
	Biological Process	Endosome To Lysosome Transport G Protein-coupled Receptor Catabolic Process	Microtubule Depolymerization Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Positive Regulation Of Microtubule Depolymerization Neuron Projection Development Cellular Response To Nerve Growth Factor Stimulus
Pathways		None	RND1 GTPase cycle
GWAS		No GWAS studies recorded	Creutzfeldt-Jakob disease ( 19081515 ) Frontotemporal dementia with GRN mutation (age at onset) ( 29724592 ) Metabolite levels ( 23823483 ) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699 ) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834 )
Interacting Genes		48 interacting genes: ADRB1 ADRB2 AGTR1 ATXN7 C8orf33 CALCR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRIP1 CXCR2 DSCAM F2R F2RL1 GLP1R GLYAT GRM1 GRM5 GRM8 HGH1 HMOX2 HTR7 LAMTOR5 LRP2 MAP7D1 MLNR MTF2 OFD1 OPRD1 OPRK1 OPRL1 OPRM1 OXTR PBK PER1 PFDN1 SNAPIN STMN2 TAC3 TACR1 TACR2 TACR3 TBXA2R TFG TRAF4 VIPR1	28 interacting genes: CCDC85A CCHCR1 CDC42 CDK1 CEP70 CTNNA3 EEF1A1 ERBB2 FAM90A1 FANCC GPRASP1 GPRASP2 MAPK10 MAPK3 MBD3 NGFR NTAQ1 PRKACA PSMB1 PSMC1 RGS20 RGS6 SESTD1 TEX11 TFCP2 TRPC5 TXLNA UBE2I
Entrez ID		9737	11075
HPRD ID		02333	09003
Ensembl ID		ENSG00000198932	ENSG00000104435
Uniprot IDs		Q5JY77	Q93045
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger G Protein-coupled Acetylcholine Receptor Activity Regulation Of Blood Pressure Signal Transduction Regulation Of Smooth Muscle Contraction Trans-synaptic Signaling System Process Synaptic Signaling G Protein-coupled Peptide Receptor Activity Regulation Of System Process G Protein-coupled Acetylcholine Receptor Signaling Pathway Postsynaptic Membrane Chemical Synaptic Transmission Vascular Process In Circulatory System Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Blood Pressure Dendrite Blood Vessel Diameter Maintenance Regulation Of Tube Size Circulatory System Process G Protein-coupled Opioid Receptor Activity Acetylcholine Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Postsynaptic Signal Transduction Positive Regulation Of Muscle Contraction Plasma Membrane G Protein-coupled Opioid Receptor Signaling Pathway Cell-cell Signaling Positive Regulation Of Cytosolic Calcium Ion Concentration Smooth Muscle Contraction Signaling Regulation Of Biological Quality Positive Regulation Of Flagellated Sperm Motility Tachykinin Receptor Activity Cell Communication Regulation Of Muscle Contraction Positive Regulation Of Cilium Movement Regulation Of Blood Circulation Regulation Of Flagellated Sperm Motility Regulation Of Systemic Arterial Blood Pressure Regulation Of MAPK Cascade Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Muscle System Process Positive Regulation Of MAPK Cascade	Cytosol Calcium Channel Complex Cytoplasm Response To Epidermal Growth Factor ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Protein Phosphorylation Intracellular Signaling Cassette Phosphorylation Neuromuscular Junction MAP Kinase Activity