OXTR and LCNL1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		OXTR	LCNL1
Description		oxytocin receptor	lipocalin like 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Oxytocin Receptor Activity Vasopressin Receptor Activity	Small Molecule Binding
	Biological Process	Regulation Of Systemic Arterial Blood Pressure By Vasopressin System Process Muscle Contraction Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Female Pregnancy Lactation Cellular Response To Hormone Stimulus Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Maternal Process Involved In Parturition Regulation Of Biological Quality Positive Regulation Of Cold-induced Thermogenesis
Pathways		Vasopressin-like receptors G alpha (q) signalling events
Drugs		Vasopressin Oxytocin Carbetocin Atosiban Relcovaptan
Diseases
GWAS		Caudate activity during reward ( 28927378) Chronotype ( 30696823) Depression and alcohol dependence ( 22064162) Liver fibrosis severity in HIV/hepatitis C co-infection ( 27339598) Morning person ( 30696823)
Interacting Genes		18 interacting genes: ALAS1 ARRB2 ASH1L AVP CD81 CYFIP2 EMC10 FSCN1 GPRASP1 LCNL1 MVB12A OXT PSMA7 SIRT2 THOC5 TMEM161A TSPAN7 YIPF3	2 interacting genes: AGTR1 OXTR
Entrez ID		5021	401562
HPRD ID		01328	16983
Ensembl ID		ENSG00000180914	ENSG00000214402
Uniprot IDs		B2R9L7 P30559	Q6ZST4
PDB IDs		6TPK 7QVM 7RYC
Enriched GO Terms of Interacting Partners?		Neurohypophyseal Hormone Activity Maternal Aggressive Behavior Regulation Of Female Receptivity Female Mating Behavior Aggressive Behavior Maternal Behavior Grooming Behavior Parental Behavior Receptor Catabolic Process Mating Behavior Neuronal Dense Core Vesicle Positive Regulation Of Fatty Acid Biosynthetic Process Neuropeptide Hormone Activity Positive Regulation Of Blood Pressure Regulation Of Fatty Acid Biosynthetic Process Response To Electrical Stimulus Reproductive Behavior V1B Vasopressin Receptor Binding Positive Regulation Of Fatty Acid Metabolic Process Macrophage Fusion Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Positive Regulation Of Hindgut Contraction Oxytocin Receptor Binding Receptor Metabolic Process Negative Regulation Of Oligodendrocyte Progenitor Proliferation Cellular Response To Caloric Restriction Tarsal Gland Development Uterine Gland Development	Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Regulation Of Systemic Arterial Blood Pressure Regulation Of Vasoconstriction Blood Vessel Diameter Maintenance Regulation Of Tube Size Regulation Of Blood Pressure Angiotensin Type I Receptor Activity Oxytocin Receptor Activity Regulation Of Blood Circulation Vascular Process In Circulatory System Bradykinin Receptor Binding Circulatory System Process Phospholipase C-activating Angiotensin-activated Signaling Pathway Renin-angiotensin Regulation Of Aldosterone Production G Protein-coupled Receptor Activity Angiotensin Type II Receptor Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Maternal Process Involved In Parturition Regulation Of Systemic Arterial Blood Pressure By Vasopressin Vasopressin Receptor Activity Regulation Of Renal Sodium Excretion Regulation Of System Process Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Low-density Lipoprotein Particle Remodeling G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Macrophage Derived Foam Cell Differentiation Angiotensin-activated Signaling Pathway Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Vasoconstriction Positive Regulation Of Cholesterol Metabolic Process Positive Regulation Of Blood Pressure Regulation Of Macrophage Derived Foam Cell Differentiation Plasma Lipoprotein Particle Remodeling Protein-containing Complex Remodeling Lactation Positive Regulation Of Steroid Metabolic Process Regulation Of Cholesterol Metabolic Process System Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Rho Protein Signal Transduction Body Fluid Secretion Female Pregnancy Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Cold-induced Thermogenesis Regulation Of Steroid Metabolic Process Symbiont Entry Into Host Cell Renal System Process Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
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