OXTR

Gene Name		oxytocin receptor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Microvillus Cell-cell Adherens Junction Apical Plasma Membrane
	Molecular Function	Oxytocin Receptor Activity Vasopressin Receptor Activity Peptide Hormone Binding Peptide Binding
	Biological Process	Suckling Behavior Response To Amphetamine Regulation Of Systemic Arterial Blood Pressure By Vasopressin Muscle Contraction Cell Surface Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Heart Development Female Pregnancy Lactation Memory Positive Regulation Of Norepinephrine Secretion Telencephalon Development Sleep Positive Regulation Of Synaptic Transmission, GABAergic Response To Estradiol Response To Progesterone Cellular Response To Hormone Stimulus Response To Anoxia Response To Cytokine Social Behavior Response To Cocaine Response To Drug Maternal Behavior Sperm Ejaculation Eating Behavior Response To Peptide Hormone Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Digestive Tract Development Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Maternal Process Involved In Parturition Positive Regulation Of Penile Erection Negative Regulation Of Gastric Acid Secretion ERK1 And ERK2 Cascade Positive Regulation Of Uterine Smooth Muscle Contraction Response To Peptide
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Vasopressin-like receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs		Oxytocin Carbetocin
Diseases
GWAS		Depression and alcohol dependence ( 22064162)
Protein-protein Interactions		4 interactors: ARRB2 AVP GPRASP1 OXT
Entrez ID		5021
HPRD ID		01328
Ensembl ID		ENSG00000180914
Uniprot IDs		B2R9L7 P30559
PDB IDs
Enriched GO Terms of Interacting Partners?		Maternal Aggressive Behavior Hyperosmotic Salinity Response Aggressive Behavior Positive Regulation Of Ion Transport Regulation Of Female Receptivity Maternal Behavior Negative Regulation Of Release Of Cytochrome C From Mitochondria Female Mating Behavior Grooming Behavior Regulation Of Renal Sodium Excretion Copulation Hyperosmotic Response Regulation Of Excretion Negative Regulation Of Mitochondrion Organization Mating Behavior Response To Salt Stress Positive Regulation Of Blood Pressure Social Behavior Single-organism Behavior Mating Regulation Of Neurological System Process Regulation Of Body Fluid Levels Positive Regulation Of Peptidyl-serine Phosphorylation Behavior Receptor Metabolic Process Regulation Of Ion Transport Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Response To Osmotic Stress Regulation Of Mitochondrion Organization Renal System Process Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Transport Positive Regulation Of Synaptic Transmission Multicellular Organismal Reproductive Process Positive Regulation Of Hindgut Contraction Multicellular Organism Reproduction Regulation Of Anion Transport Response To Alkaloid Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Ion Homeostasis Regulation Of Signaling Regulation Of G-protein Coupled Receptor Protein Signaling Pathway G-protein Coupled Receptor Catabolic Process Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Regulation Of Hindgut Contraction Reproduction Regulation Of Blood Pressure Cytosolic Calcium Ion Homeostasis
Tagcloud ?		accumbens amygdaloid asds autism autistic autoradiography c57bl6 calls circuitry circuits compensative impairments interests intranasal mor mors motivation operates opioidergic opioids oprm1 oxytocin oxytocinergic physiopathology reward social socially ultrasonic